Zobrazeno 1 - 10
of 426
pro vyhledávání: '"K. Tsilidis"'
Autor:
Y. Mahamat‐Saleh, S. Rinaldi, R. Kaaks, C. Biessy, E. M. Gonzalez‐Gil, N. Murphy, C. Le Cornet, J. M. Huerta, S. Sieri, A. Tjønneland, L. Mellemkjær, M. Guevara, K. Overvad, A. Perez‐Cornago, S. Tin Tin, L. Padroni, V. Simeon, G. Masala, A. May, E. Monninkhof, S. Christakoudi, A. K. Heath, K. Tsilidis, A. Agudo, M. B. Schulze, J. Rothwell, C. Cadeau, S. Severi, E. Weiderpass, M. J. Gunter, L. Dossus
Publikováno v:
Cancer Medicine, Vol 12, Iss 11, Pp 12668-12682 (2023)
Abstract Background Excess body fatness and hyperinsulinemia are both associated with an increased risk of postmenopausal breast cancer. However, whether women with high body fatness but normal insulin levels or those with normal body fatness and hig
Externí odkaz:
https://doaj.org/article/ebf3e18aa6534bb898f0c7429b729f2a
Autor:
F. Perrier, V. Viallon, S. Ambatipudi, A. Ghantous, C. Cuenin, H. Hernandez-Vargas, V. Chajès, L. Baglietto, M. Matejcic, H. Moreno-Macias, T. Kühn, H. Boeing, A. Karakatsani, A. Kotanidou, A. Trichopoulou, S. Sieri, S. Panico, F. Fasanelli, M. Dolle, C. Onland-Moret, I. Sluijs, E. Weiderpass, J. R. Quirós, A. Agudo, J. M. Huerta, E. Ardanaz, M. Dorronsoro, T. Y. N. Tong, K. Tsilidis, E. Riboli, M. J. Gunter, Z. Herceg, P. Ferrari, I. Romieu
Publikováno v:
Clinical Epigenetics, Vol 11, Iss 1, Pp 1-13 (2019)
Abstract Background There is increasing evidence that folate, an important component of one-carbon metabolism, modulates the epigenome. Alcohol, which can disrupt folate absorption, is also known to affect the epigenome. We investigated the associati
Externí odkaz:
https://doaj.org/article/c6df8c06c9dc44ac9f7e5480ef6a1b3f
Autor:
Simon A Jones, Abbas Dehghan, Dipender Gill, Rainer Malik, Ari Ahola-Olli, Olli Raitakari, Marko Salmi, Sirpa Jalkanen, Sirkka Keinänen-Kiukaanniemi, Karl-Heinz Herzig, Marjo-Riitta Järvelin, Sylvain Sebert, Mark J Ponsford, Konstantinos K Tsilidis, Ville Karhunen, Saranya Palaniswamy, G Kees Hovingh, Juha Veijola, Juha Auvinen, Markku Timonen, Emmanouil Bouras, Areti Papadopoulou, Matthias Wielscher
Publikováno v:
BMJ Medicine, Vol 2, Iss 1 (2023)
Objective To leverage large scale genetic association data to investigate the interplay between circulating cytokines and cardiometabolic traits, and thus identifying potential therapeutic targets.Design Bi-directional Mendelian randomisation study.S
Externí odkaz:
https://doaj.org/article/ca123e8a43954a8190bcce6b00fdf891
Autor:
Margarita Cariolou, David C Muller, Dagfinn Aune, Konstantinos K Tsilidis, Georgios Markozannes, Nerea Becerra-Tomás, Rita Vieira, Katia Balducci, Doris S M Chan
Publikováno v:
BMJ Medicine, Vol 2, Iss 1 (2023)
Objective To explore the associations between adiposity indices, assessed at or after a diagnosis of prostate cancer, and mortality.Design Systematic review and meta-analysis.Data sources PubMed and Embase, from inception to 16 November 2022.Eligibil
Externí odkaz:
https://doaj.org/article/8e7982d134894d02af18e495d4c430c4
Autor:
Mirjam Kohls, Heinz Freisling, Hadrien Charvat, Isabelle Soerjomataram, Vivian Viallon, Veronica Davila-Batista, Rudolf Kaaks, Renée Turzanski-Fortner, Krasimira Aleksandrova, Matthias B. Schulze, Christina C. Dahm, Helene Tilma Vistisen, Agnetha Linn Rostgaard-Hansen, Anne Tjønneland, Catalina Bonet, Maria-Jose Sánchez, Sandra Colorado-Yohar, Giovanna Masala, Domenico Palli, Vittorio Krogh, Fulvio Ricceri, Olov Rolandsson, Sai San Moon Lu, Konstantinos K. Tsilidis, Elisabete Weiderpass, Marc J. Gunter, Pietro Ferrari, Ursula Berger, Melina Arnold
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Body mass index (BMI) and cardiometabolic comorbidities such as cardiovascular disease and type 2 diabetes have been studied as negative prognostic factors in cancer survival, but possible dependencies in the mechanisms underlying
Externí odkaz:
https://doaj.org/article/06f45a5182ad40faaa33e314217555fe
Autor:
Fernanda Morales Berstein, Daniel L McCartney, Ake T Lu, Konstantinos K Tsilidis, Emmanouil Bouras, Philip Haycock, Kimberley Burrows, Amanda I Phipps, Daniel D Buchanan, Iona Cheng, the PRACTICAL consortium, Richard M Martin, George Davey Smith, Caroline L Relton, Steve Horvath, Riccardo E Marioni, Tom G Richardson, Rebecca C Richmond
Publikováno v:
eLife, Vol 11 (2022)
Background: Epigenetic clocks have been associated with cancer risk in several observational studies. Nevertheless, it is unclear whether they play a causal role in cancer risk or if they act as a non-causal biomarker. Methods: We conducted a two-sam
Externí odkaz:
https://doaj.org/article/4e1402d624c84c12b18465047e355ffa
Autor:
Nazlisadat Seyed Khoei, Mazda Jenab, Neil Murphy, Barbara L. Banbury, Robert Carreras-Torres, Vivian Viallon, Tilman Kühn, Bas Bueno-de-Mesquita, Krasimira Aleksandrova, Amanda J. Cross, Elisabete Weiderpass, Magdalena Stepien, Andrew Bulmer, Anne Tjønneland, Marie-Christine Boutron-Ruault, Gianluca Severi, Franck Carbonnel, Verena Katzke, Heiner Boeing, Manuela M. Bergmann, Antonia Trichopoulou, Anna Karakatsani, Georgia Martimianaki, Domenico Palli, Giovanna Tagliabue, Salvatore Panico, Rosario Tumino, Carlotta Sacerdote, Guri Skeie, Susana Merino, Catalina Bonet, Miguel Rodríguez-Barranco, Leire Gil, Maria-Dolores Chirlaque, Eva Ardanaz, Robin Myte, Johan Hultdin, Aurora Perez-Cornago, Dagfinn Aune, Konstantinos K. Tsilidis, Demetrius Albanes, John A. Baron, Sonja I. Berndt, Stéphane Bézieau, Hermann Brenner, Peter T. Campbell, Graham Casey, Andrew T. Chan, Jenny Chang-Claude, Stephen J. Chanock, Michelle Cotterchio, Steven Gallinger, Stephen B. Gruber, Robert W. Haile, Jochen Hampe, Michael Hoffmeister, John L. Hopper, Li Hsu, Jeroen R. Huyghe, Mark A. Jenkins, Amit D. Joshi, Ellen Kampman, Susanna C. Larsson, Loic Le Marchand, Christopher I. Li, Li Li, Annika Lindblom, Noralane M. Lindor, Vicente Martín, Victor Moreno, Polly A. Newcomb, Kenneth Offit, Shuji Ogino, Patrick S. Parfrey, Paul D. P. Pharoah, Gad Rennert, Lori C. Sakoda, Clemens Schafmayer, Stephanie L. Schmit, Robert E. Schoen, Martha L. Slattery, Stephen N. Thibodeau, Cornelia M. Ulrich, Franzel J. B. van Duijnhoven, Korbinian Weigl, Stephanie J. Weinstein, Emily White, Alicja Wolk, Michael O. Woods, Anna H. Wu, Xuehong Zhang, Pietro Ferrari, Gabriele Anton, Annette Peters, Ulrike Peters, Marc J. Gunter, Karl-Heinz Wagner, Heinz Freisling
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-15 (2020)
Abstract Background Bilirubin, a byproduct of hemoglobin breakdown and purported anti-oxidant, is thought to be cancer preventive. We conducted complementary serological and Mendelian randomization (MR) analyses to investigate whether alterations in
Externí odkaz:
https://doaj.org/article/cae0c18ed8fa4e30b56431b7e54f5dd8
Autor:
Xiaomeng Zhang, Dipender Gill, Yazhou He, Tian Yang, Xue Li, Grace Monori, Harry Campbell, Malcolm Dunlop, Konstantinos K. Tsilidis, Maria Timofeeva, Evropi Theodoratou
Publikováno v:
Cancer Medicine, Vol 9, Iss 13, Pp 4823-4835 (2020)
Abstract Several associations between non‐genetic biomarkers and colorectal cancer (CRC) risk have been detected, but the strength of evidence and the direction of associations are not confirmed. We aimed to evaluate the evidence of these associati
Externí odkaz:
https://doaj.org/article/b6917b07e11047bd94546650b44e1b40
Autor:
Christos V. Chalitsios, Andrea Georgiou, Emmanouil Bouras, Evangelos Evangelou, Dipender Gill, Kostas K. Tsilidis, Ioanna Tzoulaki
Publikováno v:
Journal of the American Academy of Dermatology. 88:593-601
Potentially modifiable risk factors have previously been investigated only in conventional observational studies.To assess whether genetically predicted exposures to modifiable factors are associated with the risk of psoriasis.Two-sample Mendelian ra
Autor:
Zoe S. Grenville, Urwah Noor, Mathilde His, Vivian Viallon, Sabina Rinaldi, Elom K. Aglago, Pilar Amiano, Louise Brunkwall, María Dolores Chirlaque, Isabel Drake, Fabian Eichelmann, Heinz Freisling, Sara Grioni, Alicia K. Heath, Rudolf Kaaks, Verena Katzke, Ana-Lucia Mayén-Chacon, Lorenzo Milani, Conchi Moreno-Iribas, Valeria Pala, Anja Olsen, Maria-Jose Sánchez, Matthias B. Schulze, Anne Tjønneland, Konstantinos K. Tsilidis, Elisabete Weiderpass, Anna Winkvist, Raul Zamora-Ros, Timothy J. Key, Karl Smith-Byrne, Ruth C. Travis, Julie A. Schmidt
Publikováno v:
Nutrients, Vol 14, Iss 16, p 3306 (2022)
Three metabolite patterns have previously shown prospective inverse associations with the risk of aggressive prostate cancer within the European Prospective Investigation into Cancer and Nutrition (EPIC). Here, we investigated dietary and lifestyle c
Externí odkaz:
https://doaj.org/article/62763c18493642f99355c742982d3884