Zobrazeno 1 - 10
of 3 364
pro vyhledávání: '"K. Thoma"'
Autor:
Stefanie Heym, Pauline Krebs, Kristin Ott, Norbert Donhauser, Laura M. Kemeter, Florian Simon, Sebastian Millen, Andrea K. Thoma-Kress
Publikováno v:
Pathogens, Vol 13, Iss 11, p 1015 (2024)
Human T-cell leukemia virus type 1 (HTLV-1) infects CD4+ T-cells through close cell–cell contacts. The viral Tax-1 (Tax) protein regulates transcription by transactivating the HTLV-1 U3R promoter in the 5′ long terminal repeat of the integrated p
Externí odkaz:
https://doaj.org/article/06027542b56c415fba13432fcee25fd8
Publikováno v:
Journal of Pharmaceutical Sciences. 93:1860-1866
Different methods of photostabilization are presented for the very light sensitive molsidomine tablets. The incorporation of photostabilizers such as light absorber or pigments into the tablets considerably improved the photostability. Nevertheless,
Publikováno v:
Microorganisms, Vol 11, Iss 7, p 1777 (2023)
The transmission of viruses from one host to another typically occurs through horizontal or vertical pathways. The horizontal pathways include transmission amongst individuals, usually through bodily fluids or excretions, while vertical transmission
Externí odkaz:
https://doaj.org/article/b37bd1165c0d473fbd36337b6c32a843
Autor:
Annika P. Schnell, Stephan Kohrt, Aris Aristodemou, Graham P. Taylor, Charles R. M. Bangham, Andrea K. Thoma-Kress
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The viral transactivator Tax plays a key role in HTLV-1 reactivation and de novo infection. Previous approaches focused on the histone deacetylase inhibitor (HDACi) Valproate as a latency-reversing agent to boost Tax expression and expose infected ce
Externí odkaz:
https://doaj.org/article/d5ae30795175480f9124a59a7faf0ebb
Autor:
Sebastian Millen, Lina Meretuk, Tim Göttlicher, Sarah Schmitt, Bernhard Fleckenstein, Andrea K. Thoma-Kress
Publikováno v:
Retrovirology, Vol 17, Iss 1, Pp 1-19 (2020)
Abstract Background Human T-cell leukemia virus type 1 (HTLV-1) infects primarily CD4+ T-lymphocytes and evoques severe diseases, predominantly Adult T-Cell Leukemia/ Lymphoma (ATL/L) and HTLV-1-associated Myelopathy/ Tropical Spastic Paraparesis (HA
Externí odkaz:
https://doaj.org/article/079475ccf1fc484fa52d349079011c8c
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Breastfeeding is recommended by the World Health Organization for at least 6 months up to 2 years of age, and breast milk protects against several diseases and infections. Intriguingly, few viruses are transmitted via breastfeeding including Human T-
Externí odkaz:
https://doaj.org/article/c1198c3ef1574ca48fcddccd4c7a7a47
Publikováno v:
Journal of Pharmaceutical Sciences; July 2004, Vol. 93 Issue: 7 p1860-1866, 7p
Autor:
Norbert Donhauser, Eileen Socher, Sebastian Millen, Stefanie Heym, Heinrich Sticht, Andrea K Thoma-Kress
Publikováno v:
PLoS Pathogens, Vol 16, Iss 9, p e1008879 (2020)
The Human T-cell leukemia virus type 1 (HTLV-1) orf I-encoded accessory protein p8 is cleaved from its precursor p12, and both proteins contribute to viral persistence. p8 induces cellular protrusions, which are thought to facilitate transfer of p8 t
Externí odkaz:
https://doaj.org/article/3d3893a7d7e44d7bafa0f4210b4b94f4
Autor:
E. Graf
Publikováno v:
Pharmazie in Unserer Zeit. 19:39-40
Autor:
Sebastian Millen, Christine Gross, Norbert Donhauser, Melanie C. Mann, Jean-Marie Péloponèse Jr., Andrea K. Thoma-Kress
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent for Adult T-Cell Leukemia/Lymphoma (ATLL) and HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP). HTLV-1 infects CD4+ T-cells via cell-to-cell transmission requiring
Externí odkaz:
https://doaj.org/article/629219b35e6a4af585759c2ec1fa2d9b