Investigational strategies for detection and intervention in early-stage pancreatic cancer

Autor: Daniel S. Longnecker, Parviz M. Pour, Dante G. Scarpelli, Carlos Caldas, Mark S. Redston, Stephan A. Hahn, Albert B. Seymour, Ralph H. Hruban, Charles J. Yeo, Scott E. Kern, B. A. Ruggeri, A. J. P. Klein-Szanto, L. -Y. Huang, D. Lang, Åke Andr’en-Sandberg, Bertil Johansson, Eric P. Sandgren, Günter Klöppel, P. Ghadirian, G. R. Howe, John M. Howard, Henry T. Lynch, LaVonne Fusaro, Ramon Fusaro, Jane Lynch, Thomas Smyrk, Ramon M. Fusaro, Klöppel Günter, M. Sambasiva Rao, Janardan K. Reddy, Jorge Albores-Saavedra, Sara Milchgrub, Henson Donald E., David S. Klimstra, Meera R. Hameed, Arturo M. Marrero, Kevin C. Conlon, Murray F. Brennan, Andrew L. Warshaw, Thomas E. Adrian, P. Herrnanek, Ch. Wittekind, A. Altendorf-Hofmann, Howard A. Reber, Murray Korc, Michael P. Vezeridis, Richard J. Bold, B. Mark Evers, Howard E. Sperling, Guillermo Gomez, Jin Ishizuka, Courtney M. Townsend, James C. Thompson, H. Kalthoff, C. Röder, D. Henne-Bruns, B. Kremer, W. Schmiegel, Jill Palmer Smith, Ian S. Zagon, A. V. Schally, K. Szepeshazi, Y. Qin, G. Halmos, T. Ertl, K. Groot, R. -Z. Cai, C. Liebow, G. J. Poston, Nick Lemoine, Dan Beauchamp, Young S. Kim, Jenny J. L. Ho, Michael A. Hollingsworth, Hartmut Juhl, Astrid Schott, Uwe Krüger, Doris Henne-Bruns, Bernd Kremer, Holger Kalthoff, Charles J. Lightdale, Charles Liebow, Johan Permert, Gunilla T. Westermark, Glen A. Lehman, A. Nagy, H. Reile, S. Radulovic, Ana Maria Comaru-Schally, G. D. Sorenson, D. M. Pribish, F. H. Valone, V. A. Memoli, D. J. Bzik, S.-L Yao, K. A. Mangold, K-W Chang, S. Laconi, S. Hubchak, Karoly Szepeshazi, Andrew V. Schally, Marsha L. Frazier, Ester Fernandez, Rafael de Llorens, Matthias Löhr, Birgit Trautmann, Thomas Heller, Stefanie Peters, Anja Maier, Hans J. Schutt, Ira Zauner, Stefan Liebe, B. J. Tsuei, S. P. Povoski, W. Zhou, R. H. Bell, Ralph R. Dobelbower, Ephraim S. Casper, Jill P. Smith, Guozhen Liu, Elizabeth Stock, Elaine K. Orenberg, Ning Y. Yu, Dennis M. Brown, Margaret Tempero, David Colcher, P. Hermanek, F. P. Gall, Liebow Charks, Richard H. Bell

Publikováno v: International Journal of Pancreatology. 16:183-310

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85b25b08d414c514647a3e05feeb46b0
https://doi.org/10.1007/bf02944330

Effective treatment of metastatic MDA-MB-435 human estrogen-independent breast carcinomas with a targeted cytotoxic analogue of luteinizing hormone-releasing hormone AN-207

Autor: L, Chatzistamou, A V, Schally, A, Nagy, P, Armatis, K, Szepeshazi, G, Halmos

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 6(10)

A highly potent derivative of doxorubicin, 2-pyrrolinodoxorubicin (AN-201), was linked to [D-Lys6]luteinizing hormone-releasing hormone (LH-RH) to form a cytotoxic analogue, AN-207, that can be targeted to LH-RH receptors. The effects of AN-207 were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d232051e86aefa6eab40c1bfcb822f7f
https://pubmed.ncbi.nlm.nih.gov/11051271

Regression of U-87 MG human glioblastomas in nude mice after treatment with a cytotoxic somatostatin analog AN-238

Autor: H, Kiaris, A V, Schally, A, Nagy, B, Sun, K, Szepeshazi, G, Halmos

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 6(2)

Receptors for somatostatin (SST) found on brain tumors could be used for targeting of chemotherapeutic agents. This study was conducted to investigate the effects of targeted cytotoxic SST analogue AN-238, consisting of 2-pyrrolinodoxorubicin (AN-201

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a1c7295974c1be7f4bcd1e603fb2e9aa
https://pubmed.ncbi.nlm.nih.gov/10690557

Luteinizing hormone-releasing hormone antagonist Cetrorelix (SB-75) and bombesin antagonist RC-3940-II inhibit the growth of androgen-independent PC-3 prostate cancer in nude mice

Autor: A, Jungwirth, G, Galvan, J, Pinski, G, Halmos, K, Szepeshazi, R Z, Cai, K, Groot, A V, Schally

Publikováno v: The Prostate. 32(3)

Hormones like bombesin (BN)/gastrin-releasing peptide (GRP) and luteinizing hormone-releasing hormone (LH-RH) and growth factors such as epidermal growth factor (EGF) might be involved in the relapse of prostate cancer under androgen ablation therapy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::516829fa20f967fbe488f2f141ec40c9
https://pubmed.ncbi.nlm.nih.gov/9254895

Somatostatin analogues and bombesin/gastrin-releasing peptide antagonist RC-3095 inhibit the growth of human glioblastomas in vitro and in vivo

Autor: J, Pinski, A V, Schally, G, Halmos, K, Szepeshazi, K, Groot

Publikováno v: Cancer research. 54(22)

We investigated the effects of somatostatin analogues and a synthetic bombesin/gastrin-releasing peptide (GRP) antagonist on the growth of the human malignant glioma cell lines U-87MG and U-373MG transplanted to nude mice or cultured in vitro. Nude m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::56305f56ab24c121014265122650f948
https://pubmed.ncbi.nlm.nih.gov/7954420