Zobrazeno 1 - 10
of 80
pro vyhledávání: '"K. Sue O'Shea"'
Autor:
Daniel J. Schill, Durga Attili, Cynthia J. DeLong, Melvin G. McInnis, Craig N. Johnson, Geoffrey G. Murphy, K. Sue O’Shea
Publikováno v:
Cells, Vol 13, Iss 14, p 1194 (2024)
Bipolar disorder (BP) is a recurring psychiatric condition characterized by alternating episodes of low energy (depressions) followed by manias (high energy). Cortical network activity produced by GABAergic interneurons may be critical in maintaining
Externí odkaz:
https://doaj.org/article/b9ab77d288854f43a2d082a81adb890c
Autor:
Claire E. McGhee, Zhenglin Yang, Weijie Guo, Yuting Wu, Mingkuan Lyu, Cynthia J. DeLong, Shanni Hong, Yuan Ma, Melvin G. McInnis, K. Sue O’Shea, Yi Lu
Publikováno v:
ACS Central Science, Vol 7, Iss 11, Pp 1809-1820 (2021)
Externí odkaz:
https://doaj.org/article/aaffd50db49a43b8a4534a20b283c455
Autor:
Elizabeth J. Adams, Rami Khoriaty, Anna Kiseleva, Audrey C. A. Cleuren, Kärt Tomberg, Martijn A. van der Ent, Peter Gergics, Vi T. Tang, Guojing Zhu, Mark J. Hoenerhoff, K. Sue O’Shea, Thomas L. Saunders, David Ginsburg
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The COPII component SEC24 mediates the recruitment of transmembrane cargos or cargo adaptors into newly forming COPII vesicles on the ER membrane. Mammalian genomes encode four Sec24 paralogs (Sec24a-d), with two subfamilies based on sequenc
Externí odkaz:
https://doaj.org/article/4bcbdf66d6ff48cf95ab2150fccf4a2b
Autor:
Yongqun He, William D. Duncan, Daniel J. Cooper, Jens Hansen, Ravi Iyengar, Edison Ong, Kendal Walker, Omar Tibi, Sam Smith, Lucas M. Serra, Jie Zheng, Sirarat Sarntivijai, Stephan Schürer, K. Sue O’Shea, Alexander D. Diehl
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S5, Pp 237-247 (2019)
Abstract Background Stem cells and stem cell lines are widely used in biomedical research. The Cell Ontology (CL) and Cell Line Ontology (CLO) are two community-based OBO Foundry ontologies in the domains of in vivo cells and in vitro cell line cells
Externí odkaz:
https://doaj.org/article/17a11f05b62841618ea4c7ca553c05cf
Autor:
Ryan F. Townshend, Yue Shao, Sicong Wang, Chari L. Cortez, Sajedeh Nasr Esfahani, Jason R. Spence, K. Sue O’Shea, Jianping Fu, Deborah L. Gumucio, Kenichiro Taniguchi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Neural rosettes (NPC rosettes) are radially arranged groups of cells surrounding a central lumen that arise stochastically in monolayer cultures of human pluripotent stem cell (hPSC)-derived neural progenitor cells (NPC). Since NPC rosette formation
Externí odkaz:
https://doaj.org/article/9375d16dd074417da9596bd468b05bc6
Publikováno v:
Stem Cell Research, Vol 17, Iss 2, Pp 238-247 (2016)
Over-expression of the early neural inducer, Noggin, in nestin positive subventricular zone (SVZ), neural stem cells (NSC) promotes proliferation and neuronal differentiation of neural progenitors and inhibits the expression of a CNS-enriched microRN
Externí odkaz:
https://doaj.org/article/cdb20bf75617461a8779a4fbd68da584
Autor:
Kenichiro Taniguchi, Yue Shao, Ryan F. Townshend, Yu-Hwai Tsai, Cynthia J. DeLong, Shawn A. Lopez, Srimonta Gayen, Andrew M. Freddo, Deming J. Chue, Dennis J. Thomas, Jason R. Spence, Benjamin Margolis, Sundeep Kalantry, Jianping Fu, K. Sue O’Shea, Deborah L. Gumucio
Publikováno v:
Stem Cell Reports, Vol 5, Iss 6, Pp 954-962 (2015)
We demonstrate that dissociated human pluripotent stem cells (PSCs) are intrinsically programmed to form lumens. PSCs form two-cell cysts with a shared apical domain within 20 hr of plating; these cysts collapse to form monolayers after 5 days. Expre
Externí odkaz:
https://doaj.org/article/708b3ade14564d4385e90ce1c6d3c873
Publikováno v:
Stem Cell Research, Vol 14, Iss 1, Pp 79-94 (2015)
Multipotent, self-renewing stem cells are present throughout the developing nervous system remaining in discrete regions of the adult brain. In the subventricular zone (SVZ) signaling molecules, including the bone morphogenetic proteins and their sec
Externí odkaz:
https://doaj.org/article/902577f559494c999984398d9d147cae
Autor:
K. Sue O'Shea, Yi Lu, Shanni Hong, Claire E. McGhee, Yuting Wu, Cynthia J. DeLong, Weijie Guo, Yuan Ma, Mingkuan Lyu, Zhenglin Yang, Melvin G. McInnis
Publikováno v:
ACS Central Science
ACS Central Science, Vol 7, Iss 11, Pp 1809-1820 (2021)
ACS Central Science, Vol 7, Iss 11, Pp 1809-1820 (2021)
Lithium has been a drug for bipolar disorders (BD) for over 70 years; however, its usage has been limited by its narrow therapeutic window (between 0.6 and 1.2 mM). Understanding the cellular distribution of lithium ions (Li+) in patient cells will o
Autor:
Rami Khoriaty, Anna Kiseleva, Thomas L. Saunders, Vi T. Tang, Guojing Zhu, Peter Gergics, Audrey C. A. Cleuren, Mark J. Hoenerhoff, Elizabeth J. Adams, Kärt Tomberg, David Ginsburg, K. Sue O'Shea, Martijn A. van der Ent
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
The COPII component SEC24 mediates the recruitment of transmembrane cargos or cargo adaptors into newly forming COPII vesicles on the ER membrane. Mammalian genomes encode four Sec24 paralogs (Sec24a-d), with two subfamilies based on sequence homolog