Zobrazeno 1 - 10
of 33
pro vyhledávání: '"K. Stockwell"'
Publikováno v:
Mine Closure 2022: 15th Conference on Mine Closure.
Akademický článek
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Autor:
D. K. A. Scheller, Lance A. Smith, Peter Jenner, Sarah Rose, Mahmoud M. Iravani, Michael J. Jackson, K. Stockwell
Publikováno v:
Experimental Neurology. 221:79-85
We previously showed that continuous infusion of rotigotine resulted in less dyskinesia than repeated pulsatile rotigotine administration or repeated oral administration of L-DOPA in MPTP-treated marmosets. Now we investigate whether continuous rotig
Autor:
Lance A. Smith, C. W. Olanow, Sarah Rose, Dieter Scheller, Michael J. Jackson, Mahmoud M. Iravani, Kayhan A. Tayarani-Binazir, K. Stockwell, Peter Jenner
Publikováno v:
Experimental Neurology. 219:533-542
Rotigotine is a novel, non-ergoline dopamine D(3)/D(2)/D(1)-receptor agonist for the treatment of Parkinson's disease that can be continuously delivered by the transdermal route to provide stable plasma levels. Continuous drug delivery should reduce
Autor:
G. Smith, M. Kurylowicz, John M. Martinis, Peter D. Barnes, Simon D. M. White, N. Mirabolfathi, Sunil Golwala, Bernard Sadoulet, Blas Cabrera, P. Meunier, Martin E. Huber, D. S. Akerib, R. J. Gaitskell, Vuk Mandic, R. M. Clarke, R. W. Schnee, P. L. Brink, K. M. Sundqvist, T. A. Shutt, M. Perillo-Isaac, Tarek Saab, W. K. Stockwell, Sae Woo Nam, D. N. Seitz
Publikováno v:
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 591:476-489
The Cryogenic Dark Matter Search (CDMS) experiment employs ultra-cold solid-state detectors to search for rare events resulting from WIMP-nucleus scattering. An innovative detector packaging and readout system has been developed to meet the unusual c
Autor:
Peter Jenner, Sarah Rose, Marion J. Perren, K. Stockwell, David Virley, Michael J. Jackson, Mahmoud M. Iravani
Publikováno v:
Experimental Neurology. 211:172-179
L-DOPA treatment of Parkinson's disease induces a high incidence of motor complications, notably dyskinesia. Longer acting dopamine agonists, e.g. ropinirole, are thought to produce more continuous dopaminergic stimulation and less severe dyskinesia.
Autor:
Alexander Breidenbach, Sarah Rose, K. Stockwell, Michael F. Jackson, Dieter Scheller, Peter Jenner, Lance A. Smith
Publikováno v:
Behavioural Pharmacology. 18:155-160
Rotigotine is a nonergolinic dopamine D3/D2/D1-receptor agonist used clinically for the treatment of Parkinson's disease. This study aimed to determine the relationship between peak antiparkinsonian activity and drug plasma levels after administratio
Autor:
Paolo Carminati, Peter Jenner, Sarah Rose, K. Stockwell, Louisa Johnson, Lance A. Smith, Michael J. Jackson
Publikováno v:
European Journal of Pharmacology. 546:82-87
Adenosine A 2a receptor antagonists may represent a novel non-dopaminergic approach to the treatment of Parkinson's disease. However, there is little information available on their ability to reverse motor deficits in 1-methyl-4-phenyl-1, 2, 3, 6-tet
Autor:
K. Stockwell, Bai-Yun Zeng, Maria Papathanou, Sarah Rose, Mahmoud M. Iravani, Peter Jenner, Michael J. Jackson, Andrew C. McCreary, Isobel Strang
Publikováno v:
King's College London
The treatment of dyskinesia in Parkinson׳s disease remains poor but H3 receptor agonists have been suggested as a novel pharmacological approach. We examined the effects of the H3 agonist, immepip, in 6-OHDA-lesioned rats exhibiting AIMs (abnormal i