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Cerebrospinal fluid biomarkers for predicting development of multiple sclerosis in acute optic neuritis: a population-based prospective cohort study

Autor: M. N. Olesen, K. Soelberg, B. Debrabant, A. C. Nilsson, S. T. Lillevang, J. Grauslund, I. Brandslund, J. S. Madsen, F. Paul, T. J. Smith, S. Jarius, N. Asgari

Publikováno v: Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-12 (2019)

Abstract Background Long-term outcome in multiple sclerosis (MS) depends on early treatment. In patients with acute optic neuritis (ON), an early inflammatory event, we investigated markers in cerebrospinal fluid (CSF), which may predict a diagnosis

Externí odkaz: https://doaj.org/article/e2be5c0a4fdc42e78e1de38391cbeb9d

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Additional file 1: of Cerebrospinal fluid biomarkers for predicting development of multiple sclerosis in acute optic neuritis: a population-based prospective cohort study

Autor: M. Olesen, K. Soelberg, B. Debrabant, A. Nilsson, S. Lillevang, J. Grauslund, I. Brandslund, J. Madsen, F. Paul, T. Smith, S. Jarius, N. Asgari

Figure S1. Correlation between intrathecal markers in isolated optic neuritis. This figure depicts the same, albeit much weaker or even absent correlations as shown for patients who later converted to multiple sclerosis (MS-ON) in Fig. 4. (PDF 123 kb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5646c87d2b39b6d2093ecfe2c2af3154

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Additional file 2: of Cerebrospinal fluid biomarkers for predicting development of multiple sclerosis in acute optic neuritis: a population-based prospective cohort study

Autor: M. Olesen, K. Soelberg, B. Debrabant, A. Nilsson, S. Lillevang, J. Grauslund, I. Brandslund, J. Madsen, F. Paul, T. Smith, S. Jarius, N. Asgari

Table S1. Logistic regression analyses for single predictors. Highlighted in bold are p values for which the odds ratio (OR) confidence interval do not overlap the value of 1, as an indicator of association between the highlighted markers and MS-ON.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9220ada3d77faddee8ccf4dbf5d8d8e3

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Additional file 6: of Cerebrospinal fluid biomarkers for predicting development of multiple sclerosis in acute optic neuritis: a population-based prospective cohort study

Autor: M. Olesen, K. Soelberg, B. Debrabant, A. Nilsson, S. Lillevang, J. Grauslund, I. Brandslund, J. Madsen, F. Paul, T. Smith, S. Jarius, N. Asgari

Figure S3.(Aâ +â B) Calibration plots for the prediction models presented as nomograms. The calibration plots assess the agreement between observations and predictions. For a well-calibrated prediction model, if a 10% risk for MS is predicted, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a1b333dfdf6a1792eede3668eb4c5f2

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Additional file 3: of Cerebrospinal fluid biomarkers for predicting development of multiple sclerosis in acute optic neuritis: a population-based prospective cohort study

Autor: M. Olesen, K. Soelberg, B. Debrabant, A. Nilsson, S. Lillevang, J. Grauslund, I. Brandslund, J. Madsen, F. Paul, T. Smith, S. Jarius, N. Asgari

Figure S2. Receiver-operating characteristic (ROC) curves for the six individual predictors that were unified in two models in Fig. 5. (PDF 142 kb)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14d1e462aa28098947f1455fcb15778a

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Substantial interobserver variation of thyroid volume and function by visual evaluation of thyroid (99m)Tc scintigraphy

Autor: Kerstin K, Soelberg, Peter, Grupe, Henrik, Boel-Jørgensen, Peter H, Jørgensen, Søren, Fast, Viveque E, Nielsen, Laszlo, Hegedüs, Steen J, Bonnema

Publikováno v: Danish medical journal. 61(2)

(99m)Tc-pertechnetate scintigraphy is much used in the evaluation of patients with nodular goitre. We investigated the ability of experienced observers to estimate the thyroid 24-h (131)I uptake (RAIU) and the thyroid volume by visual evaluation of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::98ce897b8aaaaa2b6771f6642fb38d13
https://pubmed.ncbi.nlm.nih.gov/24495880

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Evaluation of the apical sealing ability of apatite root canal sealer

Autor: R A, Barkhordar, M M, Stark, K, Soelberg

Publikováno v: Quintessence international (Berlin, Germany : 1985). 23(7)

The apical sealing ability of a tricalcium phosphate sealer was compared with that of three other sealers. Seventy roots of human incisors were cleansed and shaped and randomly assigned to one of seven groups of ten roots each. The root canal systems

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ba1f4398c0e5ddfa90cdbd93d408a49b
https://pubmed.ncbi.nlm.nih.gov/1329135

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