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PO-336 ThruPLEX® and PicoPLEX® technologies for rare alleles and copy number variation detection from cell-free DNA and single human cancer cells

Autor: A. Popkie, K. Shazand, M. Pesant, M. Carrol, K. Charizanis, E. Jan, D. Goryunov, Emmanuel Kamberov, John P. Langmore, M. Dinkelmann

Publikováno v: ESMO Open. 3:A153

Introduction Liquid biopsies provide a non-invasive method to acquire the genetic information provided in cell-free DNA (cfDNA) as well as in single circulating tumour cells. Access to this genetic information through next-generation sequencing (NGS)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f5998c6766c998214d62ec5a3e9aa624
https://doi.org/10.1136/esmoopen-2018-eacr25.366

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Progesterone as a neurosteroid: synthesis and actions in rat glial cellsProceedings of Xth International Congress on Hormonal Steroids, Quebec, Canada, 17–21 June 1998

Autor: A Do Thi, Michael Schumacher, H. Koenig, Franck Desarnaud, Ingrid Jung-Testas, K. Shazand, Etienne-Emile Baulieu

Publikováno v: The Journal of Steroid Biochemistry and Molecular Biology. 69:97-107

The central nervous system (CNS) and the peripheral nervous system (PNS) are targets for steroid hormones where they regulate important neuronal functions. Some steroid hormones are synthesized within the nervous system, either de novo from cholester

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d719cd7caa5661cfdfa91c5c69b0dd3
https://doi.org/10.1016/s0960-0760(98)00149-6

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Isolation and molecular genetic characterization of the Bacillus subtilis gene (infB) encoding protein synthesis initiation factor 2

Autor: T. Leighton, J. Tucker, K. Stansmore, Hans Uffe Sperling-Petersen, J.C. Rabinowitz, M. Grunberg-Manago, K. Shazand, R. Chiang

Publikováno v: Journal of Bacteriology. 172:2675-2687

Western blot (immunoblot) analysis of Bacillus subtilis cell extracts detected two proteins that cross-reacted with monospecific polyclonal antibody raised against Escherichia coli initiation factor 2 alpha (IF2 alpha). Subsequent Southern blot analy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9decd162308a65d6f95ba8d900f5980b
https://doi.org/10.1128/jb.172.5.2675-2687.1990

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Progesterone as a neurosteroid: synthesis and actions in rat glial cells

Autor: I, Jung-Testas, A, Do Thi, H, Koenig, F, Désarnaud, K, Shazand, M, Schumacher, E E, Baulieu

Publikováno v: The Journal of steroid biochemistry and molecular biology. 69(1-6)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b3127a359afe68822f77f17867e4bf44
https://pubmed.ncbi.nlm.nih.gov/10418983

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Akademický článek

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Akademický článek

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FAP48, a new protein that forms specific complexes with both immunophilins FKBP59 and FKBP12. Prevention by the immunosuppressant drugs FK506 and rapamycin

Autor: B, Chambraud, C, Radanyi, J H, Camonis, K, Shazand, K, Rajkowski, E E, Baulieu

Publikováno v: The Journal of biological chemistry. 271(51)

We have identified a human gene encoding a 48-kDa protein that specifically interacts with the peptidyl prolyl isomerase FK506-binding protein 59 (FKBP59) and also with the well known FKBP12. FKBP59 and FKBP12 belong to the large family of immunophil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e5234d9d3a9ad6fca643e7fc5f1cc8a9
https://pubmed.ncbi.nlm.nih.gov/8955134

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Bacillus subtilis phenylalanyl-tRNA synthetase genes: cloning and expression in Escherichia coli and B. subtilis

Autor: R J Röschenthaler, M Grunberg-Manago, K Shazand, A A Brakhage, H Putzer

Publikováno v: Journal of Bacteriology. 171:1228-1232

The genes that encode the two subunits of Bacillus subtilis phenylalanyl-tRNA synthetase were cloned from alpha lambda library of chromosomal B. subtilis DNA by specific complementation of a thermosensitive Escherichia coli pheS mutation. Both genes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ed0e9a4aab472a1b867be6886470f1
https://doi.org/10.1128/jb.171.2.1228-1232.1989

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