Zobrazeno 1 - 10
of 354
pro vyhledávání: '"K. Shankaran"'
Publikováno v:
People's Democracy; 5/6/2013, Vol. 37 Issue 19, p3-3, 1/4p
Akademický článek
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Autor:
Kort Michael E, Mark A. Matulenko, K. Shankaran, Anthony D. Piscopio, Marshall H. Parker, David M. Armistead, Steven D. Burke
Publikováno v:
The Journal of Organic Chemistry. 59:332-347
A convergent, enantioselective total synthesis of ionophore antibiotic X-14547A (indanomycin, 1) is described. The dioxanone-to-dihydropyran variant of the lactonic Ireland-Claisen rearrangement establishes the hydropyran nucleus of the «left wing»
Publikováno v:
The Journal of Organic Chemistry. 58:832-839
The total synthesis of the HMG-CoA synthase inhibitor 1233A (1), starting from either (R)-pulegone (6) or diketo ester 12, is described. The key transformations included the diastereoselective [2,3] rearrangements of allylic ethers 9 and 19 to alcoho
Publikováno v:
ChemInform. 25
Autor:
David M. Armistead, K. Shankaran, Steven D. Burke, M. H. Parker, Kort Michael E, Mark A. Matulenko, A. D. Piscopio
Publikováno v:
ChemInform. 25
Autor:
Timothy A. Blizzard, K. Shankaran
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 2:1555-1558
Preparation of novel 9-pyrrolo-9-deoxoerythromycin A analogs from 9-(S) and (R, erythromycylamines by the Clauson-Kass and Wasserman reactions is described. The biological activities of these novel analogs are also reported.
Publikováno v:
Tetrahedron Letters. 32:4655-4658
Enantioselective syntheses of (+)-fragolide and (−)-pereniporin B are detailed. Marino's lactone annulation method was employed to establish relative and absolute stereochemistry at carbon in the bicyclization substrate. Regio- and stereoselective
Publikováno v:
Journal of Clinical Gastroenterology. 25:453-455
Retroperitoneal colonic perforation in patients with ulcerative colitis is rare. We report such a case in a patient with severe ulcerative colitis without toxic dilatation in whom mediastinal and subcutaneous emphysema also developed. Unlike previous