Zobrazeno 1 - 10
of 215
pro vyhledávání: '"K. Selin"'
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 36, Iss , Pp 100720- (2024)
Background: Patients with post-acute sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection (PASC, i.e., Long COVID) have a symptom complex highly analogous to many features of myalgic encephalomyelitis/chronic fatigue syn
Externí odkaz:
https://doaj.org/article/4d0617ba54be4882b7093064af118572
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/a8377297a9a64533b9c80e019abccd62
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Older people have difficulty controlling infection with common viruses such as influenza A virus (IAV), RNA virus which causes recurrent infections due to a high rate of genetic mutation, and Epstein Barr virus (EBV), DNA virus which persists in B ce
Externí odkaz:
https://doaj.org/article/d1cd9468b62f4ff5bddb18544f8b4baa
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-14 (2021)
Abstract Background With more T cell receptor sequence data becoming available, the need for bioinformatics approaches to predict T cell receptor specificity is even more pressing. Here we present SwarmTCR, a method that uses labeled sequence data to
Externí odkaz:
https://doaj.org/article/06c2843c05004ca49def50d2919dec52
Publikováno v:
PLoS Pathogens, Vol 17, Iss 1, p e1009066 (2021)
In adult mice the severity of disease from viral infections is determined by the balance between the efficiency of the immune response and the magnitude of viral load. Here, the impact of this dynamic is examined in neonates. Newborns are highly susc
Externí odkaz:
https://doaj.org/article/283c5980f46b4f2995cfb2b21a29b21b
Autor:
Anna Gil, Larisa Kamga, Ramakanth Chirravuri-Venkata, Nuray Aslan, Fransenio Clark, Dario Ghersi, Katherine Luzuriaga, Liisa K. Selin
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Recognition modes of individual T cell receptors (TCRs) are well studied, but factors driving the selection of TCR repertoires from primary through persistent human virus infections are less well understood. Using deep sequencing, we demonst
Externí odkaz:
https://doaj.org/article/2b7944df77564095993254270d153052
Autor:
Larisa Kamga, Anna Gil, Inyoung Song, Robin Brody, Dario Ghersi, Nuray Aslan, Lawrence J Stern, Liisa K Selin, Katherine Luzuriaga
Publikováno v:
PLoS Pathogens, Vol 15, Iss 11, p e1008122 (2019)
The T cell receptor (TCR) repertoire is an essential component of the CD8 T-cell immune response. Here, we seek to investigate factors that drive selection of TCR repertoires specific to the HLA-A2-restricted immunodominant epitope BRLF1109-117 (YVLD
Externí odkaz:
https://doaj.org/article/703140853030433a8ed9e6c28be195a4
CD8 memory T cells are generated during primary infection with intracellular pathogens, such as viruses. These cells play an important role in the protection of the host upon re-infection with the same pathogen. In this study, we compare CD8 memory T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52153d48951acd3c2dcdac3f99ee0c5a
https://doi.org/10.1101/2022.12.15.520600
https://doi.org/10.1101/2022.12.15.520600
Autor:
Nuray Aslan, Levi B. Watkin, Anna Gil, Rabinarayan Mishra, Fransenio G. Clark, Raymond M. Welsh, Dario Ghersi, Katherine Luzuriaga, Liisa K. Selin
Publikováno v:
mBio, Vol 8, Iss 6 (2017)
ABSTRACT Fifty years after the discovery of Epstein-Barr virus (EBV), it remains unclear how primary infection with this virus leads to massive CD8 T-cell expansion and acute infectious mononucleosis (AIM) in young adults. AIM can vary greatly in sev
Externí odkaz:
https://doaj.org/article/c3db3a6bc1614ba8b351bb1bf8e3f93e
Autor:
Dinler A. Antunes, Maurício M. Rigo, Martiela V. Freitas, Marcus F. A. Mendes, Marialva Sinigaglia, Gregory Lizée, Lydia E. Kavraki, Liisa K. Selin, Markus Cornberg, Gustavo F. Vieira
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Immunotherapy has become one of the most promising avenues for cancer treatment, making use of the patient’s own immune system to eliminate cancer cells. Clinical trials with T-cell-based immunotherapies have shown dramatic tumor regressions, being
Externí odkaz:
https://doaj.org/article/6f7c39a6a40d44f7b1c9fa35fad2687e