Longitudinal analyses of the DNA methylome in deployed military servicemen identify susceptibility loci for post-traumatic stress disorder

Autor: Bart P. F. Rutten, Christiaan H. Vinkers, Hagit Cohen, Lotte C Houtepen, Elbert Geuze, Katie Lunnon, Gunter Kenis, Thomas M. Hyde, D.L.A. van den Hove, L. De Nijs, K. Schraut, Joel E. Kleinman, Eric Vermetten, Marco P. Boks, Gianluca Ursini, Jonathan Mill, Andrew E. Jaffe, Klaus-Peter Lesch, Rachel Yehuda, Nikolaos P. Daskalakis, Ehsan Pishva, Caroline M. Nievergelt, Lars M. T. Eijssen, Dewleen G. Baker, D.R. Weinberger, Adam X. Maihofer, Leonard C. Schalkwyk, Wolfgang Viechtbauer

Publikováno v: Molecular psychiatry, vol 23, iss 5
Molecular Psychiatry, 23(5), 1145. Nature Publishing Group
Molecular Psychiatry, 23(5), 1145-1156. Nature Publishing Group
Molecular Psychiatry, 23(5), 1145-1156
Molecular Psychiatry

In order to determine the impact of the epigenetic response to traumatic stress on post-traumatic stress disorder (PTSD), this study examined longitudinal changes of genome-wide blood DNA methylation profiles in relation to the development of PTSD sy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1418e30c256f163bd133533d61abd22c
https://doi.org/10.1038/mp.2017.120

Differential Effects of Prenatal Stress in Female 5-Htt-Deficient Mice: Towards Molecular Mechanisms of Resilience

Autor: Sissi Jakob, Harry Steinbusch, G. Ortega, Claus-Juergen Scholz, Angelika Schmitt, K. Schraut, Daniel L.A. van den Hove, Klaus-Peter Lesch

Publikováno v: Developmental Neuroscience, 36(6), 454-464. Karger

Prenatal stress (PS) exposure is known to increase the risk of developing emotional disorders like major depression in later life. However, some individuals do not succumb to adversity following developmental stress exposure, a phenomenon referred to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cf9d534a1c8c8cb893b4a1968376144
https://doi.org/10.1159/000363695

Contents Vol. 36, 2014

Autor: Claus-Jürgen Scholz, Shiva M. Singh, Raddy L. Ramos, Lisa A. Gabel, Diego Augusto Leme Correa, Druckerei Stückle, Annette C Da Costa, Peter J. Morgane, Magnus Cinthio, Peg Nopoulos, Jill McGaughy, Karolina Piorkowska, Klaus-Peter Lesch, Blair J. Hoplight, Camila Araújo Bernardino Garcia, G. Ortega, Douglas L. Rosene, Satz Mengensatzproduktion, Jennifer A. Thompson, R. Jarrett Rushmore, Maria José Alves Rocha, Vicki Anderson, Harry Steinbusch, David J. Mokler, Benjamin I. Laufer, Snjolaug Sveinsdottir, Jarod Fincher, David Ley, Angelika Schmitt, Kristbjörg Sveinsdottir, Chris Adamson, Bryan S. Richardson, Nga Yan Siu, Kathleen T. Yee, Daniel L.A. van den Hove, Brad Matushewski, Randa L. Stringer, Ana C. Amaral, Canaan Whiteneck, K. Schraut, Marc L. Seal, Carlos Ernesto Garrido Salmon, Karen Nygard, Eric Birgbauer, Sarah E. Van Dine, Magnus Gram, Morgan L. Kleiber, William J. Brunken, Carlos Henrique Rocha Catalão, Robert Hammond, Luiza da Silva Lopes, Matthias Mörgelin, Antonio Carlos dos Santos, Sissi Jakob, Janina R. Galler

Publikováno v: Developmental Neuroscience. 36

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::387be100fa0716e72da3a5b2e613d2e8
https://doi.org/10.1159/000369263

Differential effects of prenatal stress in 5-Htt deficient mice: towards molecular mechanisms of gene × environment interactions

Autor: Gunter Kenis, Klaus-Peter Lesch, Valentina Wiescholleck, Daniel L.A. van den Hove, G. Ortega, Harry Steinbusch, Susanne Kneitz, Jos Prickaerts, Sissi Brigitte Jakob, Claus-Jürgen Scholz, Angelika Schmitt, K. Schraut

Publikováno v: PLoS ONE
PLOS ONE, 6(8). Public Library of Science
PLoS ONE, Vol 6, Iss 8, p e22715 (2011)

Prenatal stress (PS) has been shown to influence the development of the fetal brain and to increase the risk for the development of psychiatric disorders in later life. Furthermore, the variation of human serotonin transporter (5-HTT, SLC6A4) gene wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::627c086e3cf3d42e74980e382f891b0a
https://pubmed.ncbi.nlm.nih.gov/21857948

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.