Zobrazeno 1 - 10
of 303
pro vyhledávání: '"K. Sarai"'
Publikováno v:
British Journal of Oral and Maxillofacial Surgery. 61:284-288
Akademický článek
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Autor:
George E. Dukes, Dag Nyholm, Bhopinder K. Sarai, Lakshmi S. Vasist, Sarah L Marrinan, Matthew E. Barton, Duncan Richards, Per M. Hellström, David J. Burn, Tal Otiker, Rachel A. Gibson
Publikováno v:
Movement Disorders
Background: Delayed gastric emptying may impairʟ-dopa absorption, contributing to motor fluctuations. We evaluated the effect of camicinal (GSK962040), a gastroprokinetic, on the absorption ofʟ-dopa and symptoms of PD. Methods: Phase II, double‐b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab00873a359c7a1fc53380d59b6b9ce
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-343107
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-343107
Autor:
Paul C. Fletcher, Kay Maltby, Kijoung Song, Karin Mogg, Louise K Hosking, Edward T. Bullmore, Duncan Richards, Mark A. Bush, Brendan P. Bradley, Pradeep J. Nathan, Hisham Ziauddeen, Dawn M. Waterworth, Mauro Zucchetto, Liling Warren, Bhopinder K. Sarai, Chris M. Dodds, Lakshmi Vasist Johnson, Sam R. Miller
Publikováno v:
Journal of Clinical Pharmacology
The mu-opioid system has a key role in hedonic and motivational processes critical to substance addiction. However, existing mu-opioid antagonists have had limited success as anti-addiction treatments. GSK1521498 is a selective and potent mu-opioid a
Autor:
Joyce F. Clark, Twanda L. Thirkill, Fitz Roy E Curry, Roger H. Adamson, R K Sarai, A Altangerel
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 302:H1929-H1935
To evaluate the hypothesis that sphingosine-1-phosphate (S1P) and cAMP attenuate increased permeability of individually perfused mesenteric microvessels through a common Rac1-dependent pathway, we measured the attenuation of the peak hydraulic conduc
Autor:
Twanda L. Thirkill, Roger H. Adamson, A Altangerel, Joyce F. Clark, Fitz Roy E Curry, R K Sarai
Publikováno v:
Cardiovascular Research. 88:344-351
Aims Although several cultured endothelial cell studies indicate that sphingosine-1-phosphate (S1P), via GTPase Rac1 activation, enhances endothelial barriers, very few in situ studies have been published. We aimed to further investigate the mechanis
Autor:
Liling Warren, Paul C. Fletcher, Louise K Hosking, Chris M. Dodds, Dawn M. Waterworth, Liam J Nestor, Lakshmi Vasist Johnson, Anna Korzeniowska, Duncan Richards, Naresh Subramaniam, Beta Win, Hisham Ziauddeen, Kay Maltby, Disala Fernando, Pradeep J. Nathan, Sam R. Miller, Edward T. Bullmore, Bhopinder K. Sarai
Publikováno v:
Neuropsychopharmacology
The A118G single-nucleotide polymorphism (SNP rs1799971) in the μ-opioid receptor gene, OPRM1, has been much studied in relation to alcohol use disorders. The reported effects of allelic variation at this SNP on alcohol-related behaviors, and on opi
Publikováno v:
DMW - Deutsche Medizinische Wochenschrift. 105:1573-1576
In a 22-year-old patient without clinical symptoms, a chylous pericardial effusion was found as cause of pericardial enlargement persisting over 7 years. Ultrasonic echocardiography, diagnostic pericardial puncture and the demonstration of chylomicro
Autor:
Fitz Roy E Curry, A Altangerel, Joyce F. Lenz, Detlev Drenckhahn, J. C. Ly, R K Sarai, Roger H. Adamson
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 294:H1188-H1196
Experiments in cultured endothelial cell monolayers demonstrate that increased intracellular cAMP strongly inhibits the acute permeability responses by both protein kinase A (PKA)-dependent and -independent pathways. The contribution of the PKA-indep
Publikováno v:
Aktuelle Traumatologie. 32:251-257
The acute haemorrhagic shock is one of the leading causes for death following severe pelvic injuries. Typical bleeding sources are fractured spongiosa surfaces, lesions of the major venous plexus or ruptures of branches originating from the iliac art