Zobrazeno 1 - 10
of 182
pro vyhledávání: '"K. Sandy Pang"'
Publikováno v:
Pharmaceutics, Vol 12, Iss 4, p 312 (2020)
The properties of the segregated flow model (SFM), which considers split intestinal flow patterns perfusing an active enterocyte region that houses enzymes and transporters (80%), were compared to those of the traditional model (TM), wherein 100% of
Externí odkaz:
https://doaj.org/article/f2951a68d3ea45c1b041c37fad74acf3
Autor:
Malcolm Rowland, K. Sandy Pang
Publikováno v:
Clinical Pharmacology & Therapeutics. 111:1205-1207
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f379dde937d9b9aac433f39f234fbb0e
https://doi.org/10.1002/cpt.2525
https://doi.org/10.1002/cpt.2525
Autor:
Keumhan Noh, Edwin C. Y. Chow, Holly P. Quach, Geny M. M. Groothuis, Rommel G. Tirona, K. Sandy Pang
Publikováno v:
Aaps journal. 24(4)
The vitamin D receptor (VDR), in addition to other nuclear receptors, the pregnane X receptor (PXR) and constitutive androstane receptor (CAR), is involved in the regulation of enzymes, transporters and receptors, and therefore intimately affects dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fdbfcbedca844754ed23d78ce32efba
http://www.scopus.com/inward/record.url?scp=85131136866&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85131136866&partnerID=8YFLogxK
Autor:
Inés de Lannoy, Victor Saldivia, Sophie R. Pan, Keumhan Noh, K. Sandy Pang, Sylvia Serson, H Benson Peng, Anja Toscan
Publikováno v:
Drug Metabolism and Disposition. 48:944-955
Amyloid-β peptides of 40 and 42 amino acid lengths, which are synthesized in neurons and degraded in the brain and liver, have the potential to aggregate and form neuritic plaques in Alzheimer disease. The kinetics of human amyloid-β (hAβ) 40 were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfbda718b78f661bc6dc65eb1813fdc0
https://doi.org/10.1124/dmd.120.090886
https://doi.org/10.1124/dmd.120.090886
Publikováno v:
Biopharmaceutics & Drug Disposition. 41:126-148
Calcitriol or 1,25-dihydroxyvitamin D3 [1,25(OH)2 D3 ] is the active ligand of the vitamin D receptor (VDR) that plays a vital role in health and disease. Vitamin D is converted to the relatively inactive metabolite, 25-hydroxyvitamin D3 [25(OH)D3 ],
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c022939b7a7f0cf2464dd437738060f
https://doi.org/10.1002/bdd.2223
https://doi.org/10.1002/bdd.2223
Autor:
Paul J. Karanicolas, Stephen Choi, Angela Jerath, Qi Joy Yang, Marcin Wasowicz, Jason Taam, K. Sandy Pang
Publikováno v:
Journal of Cardiothoracic and Vascular Anesthesia. 34:782-790
Tranexamic acid reduces blood loss and transfusion requirements with no significant thrombotic adverse effects. Postoperative seizures have been seen in cardiac surgical patients in association with patient (advanced age, underlying neurologic diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b9927cb26bab5ce7b7ded8e1b528ae7
https://doi.org/10.1053/j.jvca.2019.06.042
https://doi.org/10.1053/j.jvca.2019.06.042
Publikováno v:
Current Protocols. 1
The amyloid-β (Aβ) peptides of 40 and 42 amino acids that are implicated in Alzheimer's disease may potentially aggregate into toxic oligomers and form neuritic plaques. The enzyme-linked immunosorbent assay (ELISA) is a facile method used for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0626012596ba26e52064aef1188455f2
https://doi.org/10.1002/cpz1.253
https://doi.org/10.1002/cpz1.253
Autor:
Mackenzie A. McLaughlin, Alex P. Di Battista, Jack M. Goodman, K. Sandy Pang, Shawn G. Rhind, Ira Jacobs
Publikováno v:
Medicine & Science in Sports & Exercise. 54:427-427
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15d786975b4c89a97475c7d7a58211ef
https://doi.org/10.1249/01.mss.0000880436.44077.19
https://doi.org/10.1249/01.mss.0000880436.44077.19
Publikováno v:
The AAPS Journal
Clearance is one of the most widely quoted and applied pharmacokinetic concepts in drug development and therapy. Its foundations and associated models of drug elimination are well embedded and accepted within the scientific community. Recently, howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc246f77224f4aafe1d2ba8322889903
https://pubmed.ncbi.nlm.nih.gov/33973074
https://pubmed.ncbi.nlm.nih.gov/33973074
Autor:
Sophie R. Pan, Paul Grootendorst, K. Sandy Pang, Xiaoyu Yan, Inés de Lannoy, Paola Bukuroshi, H Benson Peng, Matthew R. Durk
Publikováno v:
Biopharmaceuticsdrug dispositionREFERENCES. 42(8)
Age, hypercholesterolemia, and vitamin D deficiency are risk factors that increase the brain accumulation of pathogenic β-amyloid peptides (40 and 42), precursors leading to Alzheimer's disease (AD) in humans. The relative changes accompanying aging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8566d7ba42012d5f4bc97506bad4a3b9
https://pubmed.ncbi.nlm.nih.gov/34219248
https://pubmed.ncbi.nlm.nih.gov/34219248