Zobrazeno 1 - 10
of 38
pro vyhledávání: '"K. S. Khuenl-Brady"'
Publikováno v:
Egyptian Journal for Aquaculture. 8:1-12
The time-course of the neuromuscular effects of vecuronium (n = 25) and atracurium (n = 25) has been compared at three different levels of maintenance dose in anaesthetized patients. Following intubation with vecuronium 0.1 mg kg-1 or atracurium 0.5
Autor:
K. S. Khuenl-Brady, Matthias Eikermann, Martine E. Prins, Andreas W. Sielenkämper, F Pühringer, Christopher Rex, Per Bo Larsen, Casper Claudius
Publikováno v:
Anesthesiology. 109:188-197
Background Sugammadex (Org 25969), a novel, selective relaxant binding agent, was specifically designed to rapidly reverse rocuronium-induced neuromuscular blockade. The efficacy and safety of sugammadex for the reversal of profound, high-dose rocuro
Autor:
W. J. Herring, T. Woo, C. A. Assaid, R. J. Lupinacci, H. J. Lemmens, M. Blobner, K. S. Khuenl-Brady
Publikováno v:
Survey of Anesthesiology. 61:124
Publikováno v:
British Journal of Anaesthesia, 78(3), 267-273. ELSEVIER SCI LTD
We have studied dose requirements, recovery times and pharmacokinetics of rocuronium in 32 intensive care patients. After an initial dose of 50 mg, rocuronium was administered as maintenance doses of 25 mg whenever two responses to train-of-four (TOF
Autor:
H. J. Sparr, K. S. Khuenl-Brady
Publikováno v:
Clinical Pharmacokinetics. 31:174-183
A new aminosteroidal neuromuscular blocking agent, rocuronium bromide, has recently been introduced into clinical practice. Its main advantage over other currently used drugs of this kind is its fast onset of action, which could render rocuronium the
Publikováno v:
European Journal of Anaesthesiology. 13:478-482
Pipecuronium bromide, a long acting non-depolarizing neuromuscular blocking agent was administered to four groups of 10 patients using the priming technique. The effects of the combination of two different priming doses (0.01 or 0.015 mg kg-1) given
Publikováno v:
Anesthesiology Clinics of North America. 11:345-360
SUMMARY Neuromuscular blocking agents, together with sedatives and analgesic drugs, provide the pharmacologic basis for controlled ventilation that can be a life-saving procedure in critically ill patients. During the last few years, an increasing nu
Publikováno v:
European Journal of Pharmacology. 222:153-156
The neuromuscular-blocking agent vecuronium bromide undergoes hydrolysis to three pharmacologically active metabolites (3-desacetyl, 17-desacetyl and 3,17-desacetyl vecuronium) which might modify the neuromuscular-blocking action of their parent comp
Publikováno v:
Acta Anaesthesiologica Scandinavica, 36(3), 260-263. Wiley
The interaction of ORG 9426, a new non-depolarizing neuromuscular blocking agent, with intravenous anaesthetic drugs (fentanyl, thiopental, midazolam, droperidol and etomidate) has been investigated in cats. During an infusion of one of the above ana
Autor:
José A. Alvarez-Gomez, Henk Rietbergen, K. S. Khuenl-Brady, José I. Lora-Tamayo, Magnus Wattwil, Bernard F. Vanacker
Publikováno v:
Anesthesia and analgesia. 110(1)
BACKGROUND: Sugammadex, a specifically designed -cyclodextrin, is a selective relaxant binding drug that rapidly reverses rocuronium-induced and, to a lesser extent, vecuronium-induced neuromuscular blockade. In this study, we compared the efficacy o