Výsledky vyhledávání - "K. S. Arnold"

Akademický článek

Isolation of allele-specific, receptor-binding-defective low density lipoproteins from familial defective apolipoprotein B-100 subjects.

Autor: K S Arnold, M E Balestra, R M Krauss, L K Curtiss, S G Young, T L Innerarity

Publikováno v: Journal of Lipid Research, Vol 35, Iss 8, Pp 1469-1476 (1994)

Familial defective apolipoprotein B-100 (FDB) is a genetic disorder apparently caused by a single amino acid substitution (Arg3500–>Gln) that disrupts the binding of low density lipoproteins (LDL) to the LDL receptor. The plasma of FDB heterozygote

Externí odkaz: https://doaj.org/article/b80692fa64d2496c8a5b1a82a01aefe9

Zobrazit plný text záznamu

Akademický článek

Receptor binding activity of lipid recombinants of apolipoprotein B-100 thrombolytic fragments.

Autor: A Corsini, C H Spilman, T L Innerarity, K S Arnold, S C Rall, Jr, J K Boyles, R W Mahley

Publikováno v: Journal of Lipid Research, Vol 28, Iss 12, Pp 1410-1423 (1987)

Apolipoprotein (apo) B-100, the protein constituent of low density lipoproteins (LDL), is the determinant responsible for LDL binding to the apoB,E(LDL) receptor on cells. The current study was designed to identify the region(s) of apoB-100 that inte

Externí odkaz: https://doaj.org/article/87c96d93b6d6489493836c1589be0789

Zobrazit plný text záznamu

13C NMR evidence that substitution of glutamine for arginine 3500 in familial defective apolipoprotein B-100 disrupts the conformation of the receptor-binding domain

Autor: Sissel Lund-Katz, T L Innerarity, L K Curtiss, Michael C. Phillips, K S Arnold

Publikováno v: Scopus-Elsevier

Familial defective apoB-100 is a genetic mutation that is characterized by abnormal low density lipoprotein (LDL) and moderate hypercholesterolemia. Heterozygotes for this disorder possess two populations of LDL. One has normal receptor binding, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b6b3f627fe11942d04d46329634741
https://doi.org/10.1016/s0021-9258(18)49900-0

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Phylogenetic analysis of the apolipoprotein B mRNA-editing region. Evidence for a secondary structure between the mooring sequence and the 3' efficiency element

Autor: M, Hersberger, S, Patarroyo-White, K S, Arnold, T L, Innerarity

Publikováno v: The Journal of biological chemistry. 274(49)

Apolipoprotein (apo) B mRNA editing is the deamination of C(6666) to uridine, which changes the codon at position 2153 from a genomically encoded glutamine (CAA) to an in-frame stop codon (UAA). The apoB mRNA-editing enzyme complex recognizes the edi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d7e47495841f68f2caa3b227fd61ad3f
https://pubmed.ncbi.nlm.nih.gov/10574922

Zobrazit plný text záznamu

The carboxyl terminus in apolipoprotein E2 and the seven amino acid repeat in apolipoprotein E-Leiden: role in receptor-binding activity

Autor: L M, Dong, T L, Innerarity, K S, Arnold, Y M, Newhouse, K H, Weisgraber

Publikováno v: Journal of lipid research. 39(6)

Both apolipoprotein (apo) E2 and apoE-Leiden (tandem repeat of amino acids 121-127) are associated with type III hyperlipoproteinemia and bind defectively to low density lipoprotein receptors. Removing the carboxyl terminus of both variants (residues

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d29fabc3ccb68c2d4a5252c6c2acc628
https://pubmed.ncbi.nlm.nih.gov/9643348

Zobrazit plný text záznamu

Human low density lipoprotein receptor fragment. Successful refolding of a functionally active ligand-binding domain produced in Escherichia coli

Autor: T, Simmons, Y M, Newhouse, K S, Arnold, T L, Innerarity, K H, Weisgraber

Publikováno v: The Journal of biological chemistry. 272(41)

The low density lipoprotein (LDL) receptor plays a key role in cholesterol homeostasis, mediating cellular uptake of lipoprotein particles by high affinity binding to its ligands, apolipoprotein (apo) B-100 and apoE. The ligand-binding domain of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9c2982f7f02d99df06eedbe7294fc709
https://pubmed.ncbi.nlm.nih.gov/9325268

Zobrazit plný text záznamu

13C NMR evidence that substitution of glutamine for arginine 3500 in familial defective apolipoprotein B-100 disrupts the conformation of the receptor-binding domain

Autor: S, Lund-Katz, T L, Innerarity, K S, Arnold, L K, Curtiss, M C, Phillips

Publikováno v: The Journal of biological chemistry. 266(5)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::724a92d4d85f664c8cfc84ac470a35bf
https://pubmed.ncbi.nlm.nih.gov/1993649

Zobrazit plný text záznamu

Nodular necrobiosis in a horse

Autor: K. S. Arnold, T. J. Nicholls, K. G. Johnston

Publikováno v: Australian Veterinary Journal. 60:148-148

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8292df12ef73af8aa48c03c6f84c64e
https://doi.org/10.1111/j.1751-0813.1983.tb05929.x

Zobrazit plný text záznamu

Beta-very low density lipoprotein uptake in cultured fibroblasts and smooth muscle cells from Watanabe heritable hyperlipidemic rabbits

Autor: M E Wernette-Hammond, K S Arnold, Z Garcia, Thomas L. Innerarity

Publikováno v: Arteriosclerosis: An Official Journal of the American Heart Association, Inc.. 9:501-510

Watanabe Heritable Hyperlipidemic (WHHL) rabbits are an important animal model used to study the effects of defective low density lipoprotein (LDL) receptors on lipoprotein metabolism. In the present study, the receptor-mediated catabolism of apolipo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1967829095dbc8469407626c6148a0d7
https://doi.org/10.1161/01.atv.9.4.501

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání