Zobrazeno 1 - 10 of 709 pro vyhledávání: '"K. Ramirez"'
2
Elektronická kniha
Standing Up to Colonial Power : The Lives of Henry Roe and Elizabeth Bender Cloud
Autor: Renya K. Ramirez
Standing Up to Colonial Power focuses on the lives, activism, and intellectual contributions of Henry Cloud (1884–1950), a Ho-Chunk, and Elizabeth Bender Cloud (1887–1965), an Ojibwe, both of whom grew up amid settler colonialism that attempted t
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3
Akademický článek
Single-cell transcriptional networks in differentiating preadipocytes suggest drivers associated with tissue heterogeneity
Autor: Alfred K. Ramirez, Simon N. Dankel, Bashir Rastegarpanah, Weikang Cai, Ruidan Xue, Mark Crovella, Yu-Hua Tseng, C. Ronald Kahn, Simon Kasif
Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
The origin of the heterogeneity of metabolic and inflammatory profiles exhibited by white adipocytes is little understood. Here, using scRNA-seq and computational methods, the authors show that differentiating preadipocytes exhibit gene expression di
Externí odkaz: https://doaj.org/article/1416263bed5c488e805d2dbdb75df926
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4
Akademický článek
The effect of low-dose isotretinoin therapy on serum androgen levels in women with acne vulgaris
Autor: Amir Feily, MD, Tahere Taheri, MD, Barbara Meier-Schiesser, MD, PhD, Dena P. Rhinehart, MD, Saeed Sobhanian, PhD, Maricarmen Colon-Diaz, PhD, Ahmad Feily, Marigdalia K. Ramirez-Fort, MD
Publikováno v: International Journal of Women's Dermatology, Vol 6, Iss 2, Pp 102-104 (2020)
Background: Acne vulgaris is a common dermatologic disease that causes significant social and psychological morbidity. Isotretinoin, as a vitamin A derivative, is the most effective agent in the treatment of acne. Evidence suggests that isotretinoin
Externí odkaz: https://doaj.org/article/633327d6dd92433088155098dccbb09a
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5
Akademický článek
FoxK1 and FoxK2 in insulin regulation of cellular and mitochondrial metabolism
Autor: Masaji Sakaguchi, Weikang Cai, Chih-Hao Wang, Carly T. Cederquist, Marcos Damasio, Erica P. Homan, Thiago Batista, Alfred K. Ramirez, Manoj K. Gupta, Martin Steger, Nicolai J. Wewer Albrechtsen, Shailendra Kumar Singh, Eiichi Araki, Matthias Mann, Sven Enerbäck, C. Ronald Kahn
Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Insulin signaling represses Forkhead transcription factor FoxO activity, which contributes to organismal metabolism. Here, the authors use proteomics to identify positively regulated insulin signaling targets FoxK1/K2 and demonstrate their role in li
Externí odkaz: https://doaj.org/article/6452f44069924205846a1027bdcd7038
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6
Akademický článek
Folate hydrolase‐1 (FOLH1) is a novel target for antibody‐based brachytherapy in Merkel cell carcinoma
Autor: M. K. Ramirez‐Fort, B. Meier‐Schiesser, K. Lachance, S. S. Mahase, C. D. Church, M. J. Niaz, H. Liu, V. Navarro, A. Nikolopoulou, D. V. Kazakov, E. Contassot, D. P. Nguyen, J. Sach, L. Hadravsky, Y. Sheng, S. T. Tagawa, X. Wu, C. S. Lange, L. E. French, P. T. Nghiem, N. H. Bander
Publikováno v: Skin Health and Disease, Vol 1, Iss 1, Pp n/a-n/a (2021)
Abstract Backgrounds Folate Hydrolase‐1 (FOLH1; PSMA) is a type II transmembrane protein, luminally expressed by solid tumour neo‐vasculature. Monoclonal antibody (mAb), J591, is a vehicle for mAb‐based brachytherapy in FOLH1+ cancers. Brachyth
Externí odkaz: https://doaj.org/article/fcb1e1522bcd4bf49a39bf54d852dc76
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8
Akademický článek
Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression
Autor: Weikang Cai, Masaji Sakaguchi, Andre Kleinridders, Gonzalo Gonzalez-Del Pino, Jonathan M. Dreyfuss, Brian T. O’Neill, Alfred K. Ramirez, Hui Pan, Jonathon N. Winnay, Jeremie Boucher, Michael J. Eck, C. Ronald Kahn
Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Despite being structurally similar, the insulin receptor (IR) and insulin growth factor I receptor (IGF1R) elicit distinct signalling pathways. Here the authors use receptor chimeras to unveil that IR and IGF1R signalling is related primarily to diff
Externí odkaz: https://doaj.org/article/c27316e5cd6942f09a89e65936cda8b3
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