Výsledky vyhledávání - "K. R. Jarvie"

Silencing of the constitutive activity of the dopamine D1B receptor. Reciprocal mutations between D1 receptor subtypes delineate residues underlying activation properties

Autor: S, Charpentier, K R, Jarvie, D M, Severynse, M G, Caron, M, Tiberi

Publikováno v: The Journal of biological chemistry. 271(45)

Recently, we have shown that the dopamine D1B/D5 receptor displays binding and coupling properties that are reminiscent of those of the constitutively activated G protein-coupled receptors when compared with the related D1A/D1 receptor subtype (Tiber

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::282c844f851ceec793a84130f0e11e22
https://pubmed.ncbi.nlm.nih.gov/8910419

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Molekulare Grundlagen der Interaktion zwischen Dopamin-(D1-/D2-)Rezeptoren

Autor: R. K. Sunahara, Z. B. Pristupa, H. B. Niznik, K. R. Jarvie

Publikováno v: Schizophrenie ISBN: 9783540592433

Zahlreiche objektive und subjektive psychomotorische Symptome werden von der Aktivitat dopaminerger Neurone und von Pharmaka beeinflust, die selektiv mit den neuronalen Dopaminrezeptoren in Wechselwirkung treten (Davis et al. 1991; Goldstein u. Deuts

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7100cbe82c8fab7742cfc578c192401b
https://doi.org/10.1007/978-3-642-79738-5_1

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High affinity agonist binding to the dopamine D3 receptor: chimeric receptors delineate a role for intracellular domains

Autor: S W, Robinson, K R, Jarvie, M G, Caron

Publikováno v: Molecular pharmacology. 46(2)

The dopamine D3 receptor, although structurally similar to the dopamine D2 receptor, has 100-fold higher affinity for agonists such as dopamine and quinpirole, when these receptors are expressed in 293 cells. Additionally, the D3 receptor has general

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a3c24f8d0215745a65009c77a619148f
https://pubmed.ncbi.nlm.nih.gov/7915820

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Heterogeneity of dopamine receptors

Autor: K R, Jarvie, M G, Caron

Publikováno v: Advances in neurology. 60

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1e03da3ee2726ad67fa5939994e104d0
https://pubmed.ncbi.nlm.nih.gov/8380525

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Glycoprotein nature of dopamine D1 receptors in the brain and parathyroid gland

Autor: K R, Jarvie, G, Booth, E M, Brown, H B, Niznik

Publikováno v: Molecular pharmacology. 36(4)

Dopamine D1 receptors can be covalently labeled with the photo-affinity ligand (+-)-7-[125I]iodo-8-hydroxy-3-methyl-1-(4-azidophenyl)-2,3,4,5-tetrah yd ro-1H-3-benzazepine ([125I]IMAB) and visualized following sodium dodecyl sulfate-polyacrylamide ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::caef70cfca424647112ca85055469fc7
https://pubmed.ncbi.nlm.nih.gov/2682204

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Reactivity of normal and VMH-lesion rats to quinine-adulterated foods: negative evidence for negative finickiness

Autor: H P, Weingarten, P K, Chang, K R, Jarvie

Publikováno v: Behavioral neuroscience. 97(2)

Much of the evidence for the existence of a negative finickiness component in the ventromedial hypothalamic (VMH) syndrome comes from studies comparing the relative reactivities of VMH and normal rats to quinine adulteration. The present experiments

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::828b727a8e2a1ef6da7a5baebbbba2b8
https://pubmed.ncbi.nlm.nih.gov/6849685

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Dopamine D2 receptor binding subunits of Mr congruent to 140,000 and 94,000 in brain: deglycosylation yields a common unit of Mr congruent to 44,000

Autor: K R, Jarvie, H B, Niznik, P, Seeman

Publikováno v: Molecular pharmacology. 34(2)

The ligand-binding subunit of the porcine striatal dopamine D2 receptor was identified by photoaffinity labeling with [125I]N-azidophenethylspiperone ([125I]NAPS). Upon photolysis, [125I]NAPS covalently incorporated into a broad band of apparent Mr c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::08239e18d55ef366f959db2e471390bb
https://pubmed.ncbi.nlm.nih.gov/2970586

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Dopamine D2 receptors retain agonist high-affinity form and guanine nucleotide sensitivity after removal of sialic acid

Autor: K R, Jarvie, H B, Niznik, N H, Bzowej, P, Seeman

Publikováno v: Journal of biochemistry. 104(5)

The ligand binding subunit of the D2 dopamine receptor (Mr approximately equal to 94,000) can be visualized by autoradiography following photoaffinity labeling with [125I]N-azidophenethylspiperone and sodium dodecyl sulfate-polyacrylamide gel electro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::27a1227f2df1da2705c4b67ffe43f38c
https://pubmed.ncbi.nlm.nih.gov/2906937

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Deglycosylation and proteolysis of photolabeled D2 dopamine receptors of the porcine anterior pituitary

Autor: K R, Jarvie, H B, Niznik

Publikováno v: Journal of biochemistry. 106(1)

Dopamine D2 receptor binding subunits of the porcine anterior pituitary were visualized by autoradiography following photoaffinity labeling with [125I]N-azidophenethylspiperone and sodium dodecyl-sulfate polyacrylamide gel electrophoresis. The ligand

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7f5f51588638f20c1b6c77af7396e04a
https://pubmed.ncbi.nlm.nih.gov/2528540

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