Zobrazeno 1 - 10
of 1 610
pro vyhledávání: '"K. Powers"'
Publikováno v:
Journal of Sport and Health Science, Vol 13, Iss 6, Pp 780-792 (2024)
The discovery that contracting skeletal muscle generates reactive oxygen species (ROS) was first reported over 40 years ago. The prevailing view in the 1980s was that exercise-induced ROS production promotes oxidation of proteins and lipids resulting
Externí odkaz:
https://doaj.org/article/04c5c1dbb21042ce98e3185878c17494
Autor:
Matthieu K Chardon, Y Curtis Wang, Marta Garcia, Emre Besler, J Andrew Beauchamp, Michael D'Mello, Randall K Powers, Charles J Heckman
Publikováno v:
eLife, Vol 12 (2024)
In this study, we develop new reverse engineering (RE) techniques to identify the organization of the synaptic inputs generating firing patterns of populations of neurons. We tested these techniques in silico to allow rigorous evaluation of their eff
Externí odkaz:
https://doaj.org/article/dca4fd6afd794d27ba7331811bbcf343
Autor:
Stephen N. Housley, Randal K. Powers, Paul Nardelli, Sebinne Lee, Kyle Blum, Guy S. Bewick, Robert W. Banks, Timothy C. Cope
Publikováno v:
Experimental Physiology, Vol 109, Iss 1, Pp 55-65 (2024)
Abstract Muscle spindles encode mechanosensory information by mechanisms that remain only partially understood. Their complexity is expressed in mounting evidence of various molecular mechanisms that play essential roles in muscle mechanics, mechanot
Externí odkaz:
https://doaj.org/article/431d12c1259649bc852d55f75cb49b5c
Autor:
Amanda K. Powers, Carole Hyacinthe, Misty R. Riddle, Young Kwang Kim, Alleigh Amaismeier, Kathryn Thiel, Brian Martineau, Emma Ferrante, Rachel L. Moran, Suzanne E. McGaugh, Tyler E. Boggs, Joshua B. Gross, Clifford J. Tabin
Publikováno v:
BMC Ecology and Evolution, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background The Mexican tetra, Astyanax mexicanus, includes interfertile surface-dwelling and cave-dwelling morphs, enabling powerful studies aimed at uncovering genes involved in the evolution of cave-associated traits. Compared to surface f
Externí odkaz:
https://doaj.org/article/570f22d9d58649c3813135d91b82d037
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 1, p e1011487 (2024)
Postinhibitory excitation is a transient overshoot of a neuron's baseline firing rate following an inhibitory stimulus and can be observed in vivo in human motoneurons. However, the biophysical origin of this phenomenon is still unknown and both refl
Externí odkaz:
https://doaj.org/article/59bec7af2f7d4104ad93e26fbef7b7a7
Autor:
Alexandra J. Lee, Dallas L. Mould, Jake Crawford, Dongbo Hu, Rani K. Powers, Georgia Doing, James C. Costello, Deborah A. Hogan, Casey S. Greene
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 20, Iss 5, Pp 912-927 (2022)
Genome-wide transcriptome profiling identifies genes that are prone to differential expression (DE) across contexts, as well as genes with changes specific to the experimental manipulation. Distinguishing genes that are specifically changed in a cont
Externí odkaz:
https://doaj.org/article/23d39b95a13b4a23a60211c9d4fe3a5c
Autor:
Hongwei Jing, David A. Korasick, Ryan J. Emenecker, Nicholas Morffy, Edward G. Wilkinson, Samantha K. Powers, Lucia C. Strader
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Auxin-driven transcriptional responses are mediated by ARF transcription factors. Here the authors characterize an F-box protein, AFF1, that regulates the accumulation, condensation, and nucleo-cytoplasmic partitioning of ARF19 and ARF7.
Externí odkaz:
https://doaj.org/article/acac31734fc6453bada8efe1cd6a4912
Autor:
Megan M Sperry, Tomiko T Oskotsky, Ivana Marić, Shruti Kaushal, Takako Takeda, Viktor Horvath, Rani K Powers, Melissa Rodas, Brooke Furlong, Mercy Soong, Pranav Prabhala, Girija Goyal, Kenneth E Carlson, Ronald J Wong, Idit Kosti, Brian L Le, James Logue, Holly Hammond, Matthew Frieman, David K Stevenson, Donald E Ingber, Marina Sirota, Richard Novak
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 5, p e1011050 (2023)
Drug repurposing requires distinguishing established drug class targets from novel molecule-specific mechanisms and rapidly derisking their therapeutic potential in a time-critical manner, particularly in a pandemic scenario. In response to the chall
Externí odkaz:
https://doaj.org/article/cfab81f7026e481d8f6ae5a6eade32cd
Autor:
Haiqing Bai, Longlong Si, Amanda Jiang, Chaitra Belgur, Yunhao Zhai, Roberto Plebani, Crystal Yuri Oh, Melissa Rodas, Aditya Patil, Atiq Nurani, Sarah E. Gilpin, Rani K. Powers, Girija Goyal, Rachelle Prantil-Baun, Donald E. Ingber
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Mechanical forces in lungs facilitate breathing motions. Here the authors use a microfluidic human lung alveolus chip to study influenza infection and find that mechanical forces from active chips also induce innate inflammatory responses via, at lea
Externí odkaz:
https://doaj.org/article/a8197b35fe0e4313b281435e947641eb
Autor:
William K. Powers
This study seeks to explain how one group of Native Americans, the Oglala Sioux, has preserved its social and cultural identity despite formidable attempts by the U.S. government to eliminate tribal societies. Treating continuity and change as two as
