Zobrazeno 1 - 10
of 69
pro vyhledávání: '"K. Parwani"'
Autor:
Kiran K. Parwani, Gianna M. Branella, Rebecca E. Burnham, Andre J. Burnham, Austre Y. Schiaffino Bustamante, Elisabetta Manuela Foppiani, Kristopher A. Knight, Brian G. Petrich, Edwin M. Horwitz, Christopher B. Doering, H. Trent Spencer
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Vγ9Vδ2 T cells represent a promising cancer therapy platform because the implementation of allogenic, off-the-shelf product candidates is possible. However, intravenous administration of human Vγ9Vδ2 T cells manufactured under good manufacturing
Externí odkaz:
https://doaj.org/article/f3f5f8f350124206a8b21fc88a9f4d24
Autor:
Gianna M. Branella, Jasmine Y. Lee, Jennifer Okalova, Kiran K. Parwani, Jordan S. Alexander, Raquel F. Arthuzo, Andrew Fedanov, Bing Yu, David McCarty, Harrison C. Brown, Shanmuganathan Chandrakasan, Brian G. Petrich, Christopher B. Doering, H. Trent Spencer
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The application of immunotherapies such as chimeric antigen receptor (CAR) T therapy or bi-specific T cell engager (BiTE) therapy to manage myeloid malignancies has proven more challenging than for B-cell malignancies. This is attributed to a shortag
Externí odkaz:
https://doaj.org/article/075381e09c6f4fada8ebe38297960f22
Autor:
Leon F. McSwain, Kiran K. Parwani, Shubin W. Shahab, Dolores Hambardzumyan, Tobey J. MacDonald, Jennifer M. Spangle, Anna Marie Kenney
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Medulloblastoma (MB) is the most common malignant brain tumor in children with standard of care consisting of surgery, radiation, and chemotherapy. Recent molecular profiling led to the identification of four molecularly distinct MB subgroups – Win
Externí odkaz:
https://doaj.org/article/c595f4316e4c4748b7e37bfac2ab45da
Autor:
Robert B. Jones, Jonathan Farhi, Miranda Adams, Kiran K. Parwani, Garrett W. Cooper, Milica Zecevic, Richard S. Lee, Andrew L. Hong, Jennifer M. Spangle
Publikováno v:
Cancer Research Communications. 2:1569-1578
The high frequency of aberrant PI3K pathway activation in hormone receptor–positive (HR+) breast cancer has led to the development, clinical testing, and approval of the p110α-selective PI3K inhibitor alpelisib. The limited clinical efficacy of al
Autor:
Jennifer M. Spangle, Andrew L. Hong, Richard S. Lee, Milica Zecevic, Garrett W. Cooper, Kiran K. Parwani, Miranda Adams, Jonathan Farhi, Robert B. Jones
Figure S2 shows on-target activity of PI3K and MLL1 inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0062b582ffb243aa55ff00c1636823df
https://doi.org/10.1158/2767-9764.22546227.v1
https://doi.org/10.1158/2767-9764.22546227.v1
Autor:
Jennifer M. Spangle, Andrew L. Hong, Richard S. Lee, Milica Zecevic, Garrett W. Cooper, Kiran K. Parwani, Miranda Adams, Jonathan Farhi, Robert B. Jones
Supplementary Table 1 shows p values for IHC staining that corresponds to the graphs shown in Figure 5D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6537deacfa372c7347122a85bb9c6cb4
https://doi.org/10.1158/2767-9764.22546215
https://doi.org/10.1158/2767-9764.22546215
Autor:
Jennifer M. Spangle, Andrew L. Hong, Richard S. Lee, Milica Zecevic, Garrett W. Cooper, Kiran K. Parwani, Miranda Adams, Jonathan Farhi, Robert B. Jones
The high frequency of aberrant PI3K pathway activation in hormone receptor–positive (HR+) breast cancer has led to the development, clinical testing, and approval of the p110α-selective PI3K inhibitor alpelisib. The limited clinical efficacy of al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c6fcce0da8f88e1b840396b92b49da3
https://doi.org/10.1158/2767-9764.c.6551121.v1
https://doi.org/10.1158/2767-9764.c.6551121.v1
Publikováno v:
Applied Sciences, Vol 11, Iss 5, p 2288 (2021)
Chemical looping combustion (CLC) is the most reliable carbon capture technology for curtailing CO2 insertion into the atmosphere. This paper presents the cold flow simulation results necessary to understand the hydrodynamic viability of the fast-flu
Externí odkaz:
https://doaj.org/article/108583304375434ab98d68803dad1448
Autor:
Jonathan Farhi, Robert B. Jones, Ashish K. Verma, Kiran K. Parwani, Kuei-Chien Tang, Benjamin Emenike, Pritha Bagchi, Monika Raj, Jennifer M. Spangle
Dynamic protein post-translation methylation is essential for cellular function, highlighted by the essential role of methylation in transcriptional regulation and its aberrant dysregulation in diseases including cancer. This underscores the importan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7738c532e74f6c6748b283fe8766f644
https://doi.org/10.1101/2022.07.22.501130
https://doi.org/10.1101/2022.07.22.501130
Autor:
Jasmine Y. Lee, Hunter C. Jonus, Arhanti Sadanand, Gianna M. Branella, Victor Maximov, Suttipong Suttapitugsakul, Matthew J. Schniederjan, Jenny Shim, Kiran K. Parwani, Andrew Fedanov, Adeiye A. Pilgrim, Jordan A. Silva, Christopher B. Doering, Ronghu Wu, H. Trent Spencer, Kelly C. Goldsmith
Publikováno v:
SSRN Electronic Journal.