Zobrazeno 1 - 10
of 1 304
pro vyhledávání: '"K. Panzer"'
Autor:
Julia K. Panzer, Alejandro Caicedo
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102399- (2023)
Summary: Pancreatic tissue slices allow functional investigations under close physiological conditions in situ. This approach is particularly advantageous for studying infiltrated and structurally damaged islets as found in T1D. More importantly, sli
Externí odkaz:
https://doaj.org/article/53136e340aaf4628b8f2f9d4b9937015
Publikováno v:
BMC Medical Education, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Deaf and hard of hearing (DHH) people are an underserved population and underrepresented among healthcare professionals. A major barrier to success for DHH healthcare professionals is obtaining effective accommodations during educ
Externí odkaz:
https://doaj.org/article/bfbd0ce828874f74a608fc2ff0870a66
Autor:
Mirza Muhammad Fahd Qadir, Silvia Álvarez-Cubela, Jonathan Weitz, Julia K. Panzer, Dagmar Klein, Yaisa Moreno-Hernández, Sirlene Cechin, Alejandro Tamayo, Joana Almaça, Helmut Hiller, Maria Beery, Irina Kusmartseva, Mark Atkinson, Stephan Speier, Camillo Ricordi, Alberto Pugliese, Alejandro Caicedo, Christopher A. Fraker, Ricardo Luis Pastori, Juan Domínguez-Bendala
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The ability to culture live pancreatic tissue slices for long periods of time would enable longitudinal studies ex vivo. Here the authors culture human and mouse pancreatic slices in a perfluorocarbon-based culture system and show stable endocrine an
Externí odkaz:
https://doaj.org/article/e297d8d44f204d96a98c13a905c50452
Publikováno v:
Diabetes. 72:769-780
Low-dose IL-2 is a promising immunotherapy in clinical trials for treating type 1 diabetes. A new IL-2 analog, IL-2/CD25 fusion protein, has been shown to more efficiently delay or prevent diabetes in NOD mice by expanding the population of activated
Autor:
Christian M. Cohrs, Julia K. Panzer, Denise M. Drotar, Stephen J. Enos, Nicole Kipke, Chunguang Chen, Robert Bozsak, Eyke Schöniger, Florian Ehehalt, Marius Distler, Ana Brennand, Stefan R. Bornstein, Jürgen Weitz, Michele Solimena, Stephan Speier
Publikováno v:
Cell Reports, Vol 31, Iss 1, Pp - (2020)
Summary: Type 2 diabetes is characterized by peripheral insulin resistance and insufficient insulin release from pancreatic islet β cells. However, the role and sequence of β cell dysfunction and mass loss for reduced insulin levels in type 2 diabe
Externí odkaz:
https://doaj.org/article/74611d8ea8d3455cb3cb7f860abbdb27
Low-dose IL-2 is a promising immunotherapy in clinical trials for treating type 1 diabetes. A new IL-2 analog, IL-2/CD25 fusion protein, has been shown to more efficiently delay or prevent diabetes in NOD mice by expanding the population of activated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16967a72285fc29f4e2994c235ff71bd
https://doi.org/10.2337/figshare.22280644
https://doi.org/10.2337/figshare.22280644
Autor:
Mirza Muhammad Fahd Qadir, Silvia Álvarez-Cubela, Jonathan Weitz, Julia K. Panzer, Dagmar Klein, Yaisa Moreno-Hernández, Sirlene Cechin, Alejandro Tamayo, Joana Almaça, Helmut Hiller, Maria Beery, Irina Kusmartseva, Mark Atkinson, Stephan Speier, Camillo Ricordi, Alberto Pugliese, Alejandro Caicedo, Christopher A. Fraker, Ricardo Luis Pastori, Juan Domínguez-Bendala
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/2a1cc15a96f04c4e9605fe345f65874d
Autor:
J‑M. Mallion, S. Omboni, J. Barton, W. van Mieghem, K. Narkiewicz, P‑K. Panzer, J. G. Puig, Ch. Stefanadis, R. Zwieker
Publikováno v:
Российский кардиологический журнал, Vol 0, Iss 3, Pp 74-84 (2012)
Objective. To compare the efficacy and safety of olmesartan medoxomil (O) and ramipril (R) in elderly patients with essential arterial hypertension. Methods. After a 2‑week placebo washout, 351 elderly hypertensive patients aged 65–89 years (offi
Externí odkaz:
https://doaj.org/article/f01ba07a3c4b4546950606fdf21fa0d3
Publikováno v:
Cell Reports. 41:111792
Glucagon secretion from pancreatic alpha cells is crucial to prevent hypoglycemia. For reasons still unknown, people with type 1 diabetes lose this glucoregulatory mechanism and are susceptible to dangerous hypoglycemia. Here we show that alpha cells
Autor:
Julia K. Panzer, Alejandro Caicedo
Publikováno v:
Diabetes
Life-threatening hypoglycemia is a limiting factor in the management of type 1 diabetes. People with diabetes are prone to develop hypoglycemia because they lose physiological mechanisms that prevent plasma glucose levels from falling. Among these so