Zobrazeno 1 - 10
of 25
pro vyhledávání: '"K. P. M. Heirwegh"'
Publikováno v:
Biochemical Journal. 155:405-417
Procedures for the synthesis, separation and determination of structure of the bilirubin-IX isomers are described. 1. The four biliverdin-IX isomers were prepared by oxidative cleavage of haemin and were separated as their dimethyl esters. The indivi
Publikováno v:
Enzyme. 41:75-86
Subcellular fractionation of liver homogenates from treated rats was carried out in order to study the mechanism of action of the gastrointestinal polypeptides on glucoronidation. Rats were treated for 90 min with an intravenous infusion of secretin
Autor:
P. Leroy, Norbert Blanckaert, Frans Compernolle, K. P. M. Heirwegh, Johan Fevery, R Van Houtte
Publikováno v:
Biochemical Journal. 171:203-214
1. In aqueous solution above pH7 bilirubin-IXalpha 1-O-acylglucuronide rapidly isomerizes to the non-C-1 glucuronides by sequential migration of the bilirubin acyl group from position 1 to positions 2, 3 and 4 of the sugar moiety. The transformations
Determination of bilirubin glucuronide and assay of glucuronyltransferase with bilirubin as acceptor
Autor:
K. P. M. Heirwegh, F. P. Van Roy
Publikováno v:
Biochemical Journal. 107:507-518
1. Conjugated bilirubin is conveniently determined by coupling with the diazonium salt of ethyl anthranilate. 2. This method has been used in the development of assays for UDP-glucuronyltransferase (EC 2.4.1.17), with bilirubin as substrate, in rat l
Publikováno v:
Clinica Chimica Acta. 31:109-118
1. 1. Using the diazonium salt of p-iodoaniline, bile pigments present in aqueous solution and in protein-containing systems are diazotized when the system acetoneethanol (1 : 1, v/v) is used for accelerating the reaction. After terminating the react
Publikováno v:
Journal of Clinical Investigation. 51:2482-2492
Conjugates of bilirubin were studied in normal bile of man and rat, and in bile of liver patients. In general human bile was obtained by duodenal intubation. In addition T-tube bile was examined in patients operated on for mechanical obstruction. The
Publikováno v:
Neonatology. 14:74-79
Publikováno v:
Gut. 15(2)
Moderate unconjugated hyperbilirubinaemia decreasing after pneumatic dilatation of the gastrooesophageal sphincter, so permitting a normal amount of food to be taken was observed in two patients with achalasia. Liver biopsy was performed, and hepatic