Zobrazeno 1 - 10
of 45
pro vyhledávání: '"K. P. Huber"'
Autor:
Laura Solforosi, Lea M. M. Costes, Jeroen T. B. M. Tolboom, Katherine McMahan, Tochi Anioke, David Hope, Tetyana Murdza, Michaela Sciacca, Emily Bouffard, Julia Barrett, Cindy Wu, Nicole Hachmann, Jessica Miller, Jingyou Yu, Xuan He, Catherine Jacob-Dolan, Sietske K. Rosendahl Huber, Liesbeth Dekking, Ronnie Chamanza, Ying Choi, Karin Feddes-de Boer, Dan H. Barouch, Hanneke Schuitemaker, Roland C. Zahn, Frank Wegmann
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Variant booster vaccines are a strategy to improve protection against SARS-CoV-2. Here, the authors find that both Wuhan-Hu-1-based Ad26.COV2.S or an Omicron-adapted booster vaccine provide robust immune responses and protection against Omicron in NH
Externí odkaz:
https://doaj.org/article/48f5d6d725c04fbe926ebad22c4e7481
Autor:
Ramon Roozendaal, Laura Solforosi, Daniel J. Stieh, Jan Serroyen, Roel Straetemans, Anna Dari, Muriel Boulton, Frank Wegmann, Sietske K. Rosendahl Huber, Joan E. M. van der Lubbe, Jenny Hendriks, Mathieu Le Gars, Liesbeth Dekking, Dominika N. Czapska-Casey, Nuria Guimera, Sarah Janssen, Sarah Tete, Abishek Chandrashekar, Noe B. Mercado, Jingyou Yu, Wouter Koudstaal, Juan J. Perez-Ruixo, Jerry Sadoff, Dan H. Barouch, Hanneke Schuitemaker, Roland Zahn
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Several COVID-19 vaccines have received emergency approval, but durability of protection is unclear. Here, the authors describe correlates of protection (CoP) for the Ad26.COV2.S vaccine in rhesus macaques and report that CoP predict the protection o
Externí odkaz:
https://doaj.org/article/c77c130d228d404b88e0e8b1e5e20f78
Autor:
Joan E. M. van der Lubbe, Sietske K. Rosendahl Huber, Aneesh Vijayan, Liesbeth Dekking, Ella van Huizen, Jessica Vreugdenhil, Ying Choi, Miranda R. M. Baert, Karin Feddes-de Boer, Ana Izquierdo Gil, Marjolein van Heerden, Tim J. Dalebout, Sebenzile K. Myeni, Marjolein Kikkert, Eric J. Snijder, Leon de Waal, Koert J. Stittelaar, Jeroen T. B. M. Tolboom, Jan Serroyen, Leacky Muchene, Leslie van der Fits, Lucy Rutten, Johannes P. M. Langedijk, Dan H. Barouch, Hanneke Schuitemaker, Roland C. Zahn, Frank Wegmann
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-12 (2021)
Abstract Previously we have shown that a single dose of recombinant adenovirus serotype 26 (Ad26) vaccine expressing a prefusion stabilized SARS-CoV-2 spike antigen (Ad26.COV2.S) is immunogenic and provides protection in Syrian hamster and non-human
Externí odkaz:
https://doaj.org/article/fc2cb2bea71d44b4a49590c0dc2b55f2
Autor:
Sietske K. Rosendahl Huber, Marion Hendriks, Ronald H. J. Jacobi, Jan van de Kassteele, Jolanda C. Mandersloot-Oskam, Renée A. J. van Boxtel, Anne M. J. Wensing, Nynke Y. Rots, Willem Luytjes, Josine van Beek
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
While currently used influenza vaccines are designed to induce neutralizing antibodies, little is known on T cell responses induced by these vaccines. The 2009 pandemic provided us with the opportunity to evaluate the immune response to vaccination i
Externí odkaz:
https://doaj.org/article/799d83e6c6c446b2b3a44cdde24ce654
Autor:
L. Charlotte J. de Bree, Renoud J. Marijnissen, Junda M. Kel, Sietske K. Rosendahl Huber, Peter Aaby, Christine Stabell Benn, Marcel V. W. Wijnands, Dimitri A. Diavatopoulos, Reinout van Crevel, Leo A. B. Joosten, Mihai G. Netea, John Dulos
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Externí odkaz:
https://doaj.org/article/7f8678b8cd804c5489ae3fcebda8bf59
Autor:
L. Charlotte J. de Bree, Renoud J. Marijnissen, Junda M. Kel, Sietske K. Rosendahl Huber, Peter Aaby, Christine Stabell Benn, Marcel V. W. Wijnands, Dimitri A. Diavatopoulos, Reinout van Crevel, Leo A. B. Joosten, Mihai G. Netea, John Dulos
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Avian influenza A of the subtype H7N9 has been responsible for almost 1,600 confirmed human infections and more than 600 deaths since its first outbreak in 2013. Although sustained human-to-human transmission has not been reported yet, further adapta
Externí odkaz:
https://doaj.org/article/7a86a7e49a1b4fd5a94f8b6ec52de8d7
Autor:
Peter C. Soema, Sietske K. Rosendahl Huber, Geert-Jan Willems, Ronald Jacobi, Marion Hendriks, Ernst Soethout, Wim Jiskoot, Jørgen de Jonge, Josine van Beek, Gideon F. A. Kersten, Jean-Pierre Amorij
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Influenza peptide antigens coding for conserved T cell epitopes have the capacity to induce cross-protective influenza-specific immunity. Short peptide antigens used as a vaccine, however, often show poor immunogenicity. In this study, we demonstrate
Externí odkaz:
https://doaj.org/article/688c54d00d8745a7ae75b0cdd6a09d4a
Autor:
Sietske K Rosendahl Huber, Jolien J Luimstra, Josine van Beek, Rieuwert Hoppes, Ronald H J Jacobi, Marion Hendriks, Kim Kapteijn, Casper Ouwerkerk, Boris Rodenko, Huib Ovaa, Jørgen de Jonge
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156462 (2016)
T cells are essential players in the defense against infection. By targeting the MHC class I antigen-presenting pathway with peptide-based vaccines, antigen-specific T cells can be induced. However, low immunogenicity of peptides poses a challenge. H
Externí odkaz:
https://doaj.org/article/932165a9574145e3b1a7b4fb759dfbc2
Autor:
Esther J. M. Stoop, Tim Schipper, Sietske K. Rosendahl Huber, Alexander E. Nezhinsky, Fons J. Verbeek, Sudagar S. Gurcha, Gurdyal S. Besra, Christina M. J. E. Vandenbroucke-Grauls, Wilbert Bitter, Astrid M. van der Sar
Publikováno v:
Disease Models & Mechanisms, Vol 4, Iss 4, Pp 526-536 (2011)
SUMMARY The hallmark of tuberculosis (TB) is the formation of granulomas, which are clusters of infected macrophages surrounded by additional macrophages, neutrophils and lymphocytes. Although it has long been thought that granulomas are beneficial f
Externí odkaz:
https://doaj.org/article/41d51854f4b84a878b3f42292ea9414f
Autor:
S K Rosendahl Huber, M G M Camps, R H J Jacobi, J Mouthaan, H van Dijken, J van Beek, F Ossendorp, J de Jonge
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0127969 (2015)
Currently licensed influenza vaccines mainly induce antibodies against highly variable epitopes. Due to antigenic drift, protection is subtype or strain-specific and regular vaccine updates are required. In case of antigenic shifts, which have caused
Externí odkaz:
https://doaj.org/article/1edd94224da04dc981f550d125369caf