Zobrazeno 1 - 10
of 313
pro vyhledávání: '"K. P., Lim"'
Autor:
Berdjette Y. Y. Lau, Cassandra X. C. Chan, Xin Le Ng, Dawn K. A. Lim, Blanche X. H. Lim, Chris H. L. Lim
Publikováno v:
Hygiene, Vol 4, Iss 3, Pp 258-268 (2024)
In light of the close contact between patient and clinician during ophthalmic examinations and the multiple opportunities for pathogen transmission, we identified and evaluated potential pathogen transmission routes through high-touch surfaces in an
Externí odkaz:
https://doaj.org/article/6dd48500127f4cafa72d1196863c7b3f
Autor:
Paul Trlin, Jenny Gong, Katie K. N. Tran, Vickie H. Y. Wong, Pei Ying Lee, Anh Hoang, Da Zhao, Leah C. Beauchamp, Jeremiah K. H. Lim, Andrew Metha, Kevin J. Barnham, David I. Finkelstein, Bang V. Bui, Phillip Bedggood, Christine T. O. Nguyen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Retinal hyperspectral imaging (HSI) is a non-invasive in vivo approach that has shown promise in Alzheimer’s disease. Parkinson’s disease is another neurodegenerative disease where brain pathobiology such as alpha-synuclein and iron over
Externí odkaz:
https://doaj.org/article/4922d8416bbd4e5ca8336a9df43afadf
Autor:
Jonathan K. M. Lim, Arash Samiei, Alberto Delaidelli, Jessica Oliveira de Santis, Vanessa Brinkmann, Christopher J. Carnie, Daniel Radiloff, Laura Hruby, Alisa Kahler, Jordan Cran, Gabriel Leprivier, Poul H. Sorensen
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-10 (2024)
Abstract Eukaryotic elongation factor 2 (eEF2) kinase (eEF2K) is a stress-responsive hub that inhibits the translation elongation factor eEF2, and consequently mRNA translation elongation, in response to hypoxia and nutrient deprivation. EEF2K is als
Externí odkaz:
https://doaj.org/article/6835837b84d7441fa2ee38d01cd997d9
Autor:
Tal Levy, Kai Voeltzke, Laura Hruby, Khawla Alasad, Zuelal Bas, Marteinn Snaebjörnsson, Ran Marciano, Katerina Scharov, Mélanie Planque, Kim Vriens, Stefan Christen, Cornelius M. Funk, Christina Hassiepen, Alisa Kahler, Beate Heider, Daniel Picard, Jonathan K. M. Lim, Anja Stefanski, Katja Bendrin, Andres Vargas-Toscano, Ulf D. Kahlert, Kai Stühler, Marc Remke, Moshe Elkabets, Thomas G. P. Grünewald, Andreas S. Reichert, Sarah-Maria Fendt, Almut Schulze, Guido Reifenberger, Barak Rotblat, Gabriel Leprivier
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Energetic stress compels cells to evolve adaptive mechanisms to adjust their metabolism. Inhibition of mTOR kinase complex 1 (mTORC1) is essential for cell survival during glucose starvation. How mTORC1 controls cell viability during glucose
Externí odkaz:
https://doaj.org/article/b77120ef8e324fda80f5122560600dc1
Autor:
S. H. Ooi, K. P. Ng, Pavai Sthaneshwar, S. K. Lim, P. Y. Khor, J. Y. Lim, W. S. Siow, K. W. Lim, Muhummad Azlan
Publikováno v:
BMC Nephrology, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background The commonest indication for hospitalization in COVID-19 patients is hypoxemia or severe respiratory symptoms. However, COVID-19 disease may result in extrapulmonary complications including kidney-related pathology. The reported i
Externí odkaz:
https://doaj.org/article/528f9a6edbf4412bad5e3db295d4a893
Autor:
Qiu Xuan Tan, Nicholas B. Shannon, Weng Khong Lim, Jing Xian Teo, Daniel R. Y. Yap, Sze Min Lek, Joey W. S. Tan, Shih Jia J. Tan, Josephine Hendrikson, Ying Liu, Gillian Ng, Clara Y. L. Chong, Wanyu Guo, Kelvin K. N. Koh, Cedric C. Y. Ng, Vikneswari Rajasegaran, Jolene S.M. Wong, Chin Jin Seo, Choon Kiat Ong, Tony K. H. Lim, Bin Tean Teh, Oi Lian Kon, Claramae S. Chia, Khee Chee Soo, N. Gopalakrishna Iyer, Chin-Ann J. Ong
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionField cancerization is suggested to arise from imbalanced differentiation in individual basal progenitor cells leading to clonal expansion of mutant cells that eventually replace the epithelium, although without evidence.MethodsWe perform
Externí odkaz:
https://doaj.org/article/281912497fc44f628bdcedeb2a207a97
Autor:
Paul S. Sidhu, Caroline Ewertsen, Maciej Piskunowicz, Mustafa Secil, Paolo Ricci, Thomas Fischer, Diana Gaitini, Vladimir Mitkov, Adrian K. P. Lim, Qiang Lu, Wui K. Chong, Dirk Andre Clevert
Publikováno v:
Insights into Imaging, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Ultrasound practice is a longstanding tradition for radiology departments, being part of the family of imaging techniques. Ultrasound is widely practiced by non-radiologists but becoming less popular within radiology. The position of ultraso
Externí odkaz:
https://doaj.org/article/e57f870ba43f400183dd0bbf8edd1395
Autor:
Alain Tremblay, Ranjani Somayaji, Arthur Lau, Fatma Eser, Rahmet Guner, David R Luke, Ŏ Fehmi Tabak, Mark Hepokoski, Nancy Gardetto, Steven A Conrad, Sunil D Kumar, Kalyan Ghosh, Stephen M Robbins, Donna L Senger, Daisy Sun, Rachel K S Lim, Jonathan Liu, Ridvan Karaali, Daniel Muruve
Publikováno v:
BMJ Open, Vol 14, Iss 3 (2024)
Objective Dipeptidase-1 (DPEP-1) is a recently discovered leucocyte adhesion receptor for neutrophils and monocytes in the lungs and kidneys and serves as a potential therapeutic target to attenuate inflammation in moderate-to-severe COVID-19. We aim
Externí odkaz:
https://doaj.org/article/ce794de0f6f943398e235ef10b530862
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-17 (2023)
Abstract Background Cysteine-dense peptides (CDPs) are an attractive pharmaceutical scaffold that display extreme biochemical properties, low immunogenicity, and the ability to bind targets with high affinity and selectivity. While many CDPs have pot
Externí odkaz:
https://doaj.org/article/2ef221f1244a441880541c7820f01406
Autor:
Qiao Jin, Eric S. H. Lau, Andrea O. Luk, Claudia H. T. Tam, Risa Ozaki, Cadmon K. P. Lim, Hongjiang Wu, Elaine Y. K. Chow, Alice P. S. Kong, Heung Man Lee, Baoqi Fan, Alex C. W. Ng, Guozhi Jiang, Ka Fai Lee, Shing Chung Siu, Grace Hui, Chiu Chi Tsang, Kam Piu Lau, Jenny Y. Leung, Man-wo Tsang, Elaine Y. N. Cheung, Grace Kam, Ip Tim Lau, June K. Li, Vincent T. Yeung, Emmy Lau, Stanley Lo, Samuel Fung, Yuk Lun Cheng, Chun Chung Chow, Weichuan Yu, Stephen K. W. Tsui, Yu Huang, Hui-yao Lan, Cheuk Chun Szeto, Wing Yee So, Alicia J. Jenkins, Juliana C. N. Chan, Ronald C. W. Ma, the Hong Kong Diabetes Biobank Study Group
Publikováno v:
Cardiovascular Diabetology, Vol 21, Iss 1, Pp 1-13 (2022)
Abstract Objective High-density lipoproteins (HDL) comprise particles of different size, density and composition and their vasoprotective functions may differ. Diabetes modifies the composition and function of HDL. We assessed associations of HDL siz
Externí odkaz:
https://doaj.org/article/e336dcac29d4420fbaf4aba48277595d