Zobrazeno 1 - 10
of 310
pro vyhledávání: '"K. Oehler"'
Autor:
Riya Khetan, Preethi Eldi, Noor A. Lokman, Carmela Ricciardelli, Martin K. Oehler, Anton Blencowe, Sanjay Garg, Katherine Pillman, Hugo Albrecht
Publikováno v:
Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-13 (2024)
Abstract Genetic heterogeneity in ovarian cancer indicates the need for personalised treatment approaches. Currently, very few G-protein coupled receptors (GPCRs) have been investigated for active targeting with nanomedicines such as antibody-conjuga
Externí odkaz:
https://doaj.org/article/c01647f0a122462aaa86f0867aefdd8e
Autor:
Veronika Bandara, Jade Foeng, Batjargal Gundsambuu, Todd S. Norton, Silvana Napoli, Dylan J. McPeake, Timona S. Tyllis, Elaheh Rohani-Rad, Caitlin Abbott, Stuart J. Mills, Lih Y. Tan, Emma J. Thompson, Vasiliki M. Willet, Victoria J. Nikitaras, Jieren Zheng, Iain Comerford, Adam Johnson, Justin Coombs, Martin K. Oehler, Carmela Ricciardelli, Allison J. Cowin, Claudine S. Bonder, Michael Jensen, Timothy J. Sadlon, Shaun R. McColl, Simon C. Barry
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Chimeric antigen receptor (CAR)-T cell immunotherapy is a novel treatment that genetically modifies the patients’ own T cells to target and kill malignant cells. However, identification of tumour-specific antigens expressed on multiple sol
Externí odkaz:
https://doaj.org/article/a5287b5698b04be1aa66caa9922e1384
Autor:
Anwar Mulugeta, Amanda L. Lumsden, Iqbal Madakkatel, David Stacey, S. Hong Lee, Johanna Mäenpää, Martin K. Oehler, Elina Hyppönen
Publikováno v:
Cancer Medicine, Vol 13, Iss 4, Pp n/a-n/a (2024)
Abstract Background Ovarian cancer (OC) is commonly diagnosed among older women who have comorbidities. This hypothesis‐free phenome‐wide association study (PheWAS) aimed to identify comorbidities associated with OC, as well as traits that share
Externí odkaz:
https://doaj.org/article/19f94eb9333c499eaa18905480e8678d
Autor:
Veronika Bandara, Victoria M Niktaras, Vasiliki J Willett, Hayley Chapman, Noor A Lokman, Anne M Macpherson, Silvana Napoli, Batjargal Gundsambuu, Jade Foeng, Timothy J Sadlon, Justin Coombs, Shaun R McColl, Simon C Barry, Martin K Oehler, Carmela Ricciardelli
Publikováno v:
Clinical & Translational Immunology, Vol 13, Iss 5, Pp n/a-n/a (2024)
Abstract Objectives Recent studies have identified expression of the non‐functional P2X7 (nfP2X7) receptor on various malignant cells including ovarian cancer, but not on normal cells, which makes it a promising tumour‐associated antigen candidat
Externí odkaz:
https://doaj.org/article/a34eb2d9adae4c50973532aecbe3bf90
Autor:
Dilys Leung, Zoe K. Price, Noor A. Lokman, Wanqi Wang, Lizamarie Goonetilleke, Elif Kadife, Martin K. Oehler, Carmela Ricciardelli, George Kannourakis, Nuzhat Ahmed
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-23 (2022)
Abstract Background Epithelial ovarian cancer is the most lethal gynaecological cancer worldwide. Chemotherapy resistance represents a significant clinical challenge and is the main reason for poor ovarian cancer prognosis. We identified novel expres
Externí odkaz:
https://doaj.org/article/0bf982e54f6942ba87713c8c2e280ab1
Publikováno v:
Gynecologic Oncology Reports, Vol 48, Iss , Pp 101201- (2023)
We present the case of a 59-year-old woman who developed a right thigh pleomorphic sarcoma with rhabdomyoblastic differentiation 6 years following radiotherapy for a vaginal squamous cell carcinoma. The overall 5-year survival for a gynaecological ma
Externí odkaz:
https://doaj.org/article/666be3402ffe406badb916a3a4bc62f4
Autor:
Andrew N. Stephens, Simon J. Hobbs, Sung-Woog Kang, Martin K. Oehler, Tom W. Jobling, Richard Allman
Publikováno v:
Diagnostics, Vol 14, Iss 7, p 671 (2024)
Pre-surgical clinical assessment of an adnexal mass is a complex process, and ideally requires accurate and rapid identification of disease status. Gold standard biomarker CA125 is extensively used off-label for this purpose; however its performance
Externí odkaz:
https://doaj.org/article/1568315bfe9741edb1e0755dc4e4414e
Autor:
Muhammed H. Rahaman, Frankie Lam, Longjin Zhong, Theodosia Teo, Julian Adams, Mingfeng Yu, Robert W. Milne, Chris Pepper, Noor A. Lokman, Carmela Ricciardelli, Martin K. Oehler, Shudong Wang
Publikováno v:
Molecular Oncology, Vol 13, Iss 10, Pp 2178-2193 (2019)
Colorectal cancer (CRC) remains one of the most lethal human malignancies, and pursuit of new therapeutic targets for treatment has been a major research focus. Cyclin‐dependent kinase 9 (CDK9), which plays a crucial role in transcription, has emer
Externí odkaz:
https://doaj.org/article/cbaa876250d345bd9ed140b6e56eb1f2
Publikováno v:
Case Reports in Oncology, Vol 12, Iss 2, Pp 573-580 (2019)
Vulval basal cell carcinomas (BCC) are an important differential diagnosis of painful, itchy vulval lesions, which can occur at all ages but commonly affect women in their senium. BCC tend to grow locally in an invasive and destructive pattern and se
Externí odkaz:
https://doaj.org/article/8489ffd45b3a40d59547fca8d68b461b