Zobrazeno 1 - 10
of 135
pro vyhledávání: '"K. O'Dowd"'
Autor:
Miranda L. van Hooff, Johanna E. Vriezekolk, Robert Jan Kroeze, John K. O’Dowd, Jacques van Limbeek, Maarten Spruit
Publikováno v:
BMC Musculoskeletal Disorders, Vol 22, Iss 1, Pp 1-9 (2021)
Abstract Background Multidisciplinary pain management programs based on cognitive behavioral training (CBT) principles have been shown moderately effective in improving daily functioning in patients with chronic low back pain (CLBP). To optimize heal
Externí odkaz:
https://doaj.org/article/1519a75e1bfb4224be4b50aabc38e778
Autor:
Yunyao Xie, Nathan N. Ng, Olga S. Safrina, Carmen M. Ramos, Kevin C. Ess, Philip H. Schwartz, Martin A. Smith, Diane K. O'Dowd
Publikováno v:
Neurobiology of Disease, Vol 134, Iss , Pp - (2020)
Over 1250 mutations in SCN1A, the Nav1.1 voltage-gated sodium channel gene, are associated with seizure disorders including GEFS+. To evaluate how a specific mutation, independent of genetic background, causes seizure activity we generated two pairs
Externí odkaz:
https://doaj.org/article/2a3cbc5f5bc0474cb3ebb39b14134cf2
Publikováno v:
Stem Cell Research, Vol 26, Iss , Pp 84-94 (2018)
The use of human induced pluripotent stem cell (hiPSC)-derived neuronal cultures to study the mechanisms of neurological disorders is often limited by low efficiency and high variability in differentiation of functional neurons. Here we compare the f
Externí odkaz:
https://doaj.org/article/726e5342292e494fb341f65e0d078815
Publikováno v:
eLife, Vol 8 (2019)
Institutions should value teaching and service, and not just research, when considering faculty for promotion and tenure
Externí odkaz:
https://doaj.org/article/673ade0025f84e9286ad171712073c33
Autor:
Lynn C. Reimer, Katerina Schenke, Tutrang Nguyen, Diane K. O'Dowd, Thurston Domina, Mark Warschauer
Publikováno v:
RSF: The Russell Sage Foundation Journal of the Social Sciences, Vol 2, Iss 1, Pp 212-233 (2016)
Over the course of one year, we systematically observed instruction in nearly all large gateway STEM courses at the University of California, Irvine to assess the prevalence of promising instructional practices and their implications for student succ
Externí odkaz:
https://doaj.org/article/32ef1e3d1b874c379de188a9c210425f
Publikováno v:
International Review of Research in Open and Distributed Learning, Vol 15, Iss 5 (2014)
There is concern that online education may widen the achievement gap between students from different socioeconomic classes. The recent discussion of integrating massive open online courses (MOOCs) into formal higher education has added fuel to this d
Externí odkaz:
https://doaj.org/article/20ee4d70a7764e6eb023527f29845e5f
Akademický článek
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Publikováno v:
Journal of Visualized Experiments.
Transgenic mouse models have proved to be powerful tools in studying various aspects of human neurological disorders, including epilepsy. The SCN1A-associated genetic epilepsies comprise a wide spectrum of seizure disorders with incomplete penetrance
Autor:
Soleil S. Schutte, Jonathan Neumann, Bingyao Zhu, Diane K. O'Dowd, Grant R. MacGregor, Olga Safrina, Robert F. Hunt, Daniel R. Benavides, Lisha Zeng, An T. Pham, Yunyao Xie, Antara Das
Publikováno v:
eNeuro, vol 8, iss 2
eNeuro
eNeuro
Advances in genome sequencing have identified over 1300 mutations in theSCN1Asodium channel gene that result in genetic epilepsies. However, it still remains unclear how most individual mutations withinSCN1Aresult in seizures. A previous study has sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::111daec53c4826bd8d7a13e15eef87fa
https://escholarship.org/uc/item/1b90h1jm
https://escholarship.org/uc/item/1b90h1jm
Autor:
Alexa Joanna, Roemmich, Thy, Vu, Tamas, Lukacsovich, Charlesice, Hawkins, Soleil S, Schutte, Diane K, O'Dowd
Publikováno v:
eNeuro
Mutations in the voltage-gated sodium channel gene SCN1A are associated with human epilepsy disorders, but how most of these mutations alter channel properties and result in seizures is unknown. This study focuses on two different mutations occurring