Výsledky vyhledávání - "K. N. Kolyasnikova"

Akademický článek

The effects of cycloprolylglycine and its analogues on brain monoaminergic systems in BALB/c mice

Autor: A. A. Abdullina, E. V. Vasileva, V. S. Kudrin, V. B Narkevich, T. A. Gudasheva, K. N. Kolyasnikova, G. I. Kovalev

Publikováno v: Фармакокинетика и Фармакодинамика, Vol 0, Iss 1, Pp 3-10 (2020)

Effects of chronic cycloprolylglycine (CPG) and its analogues GZK-001 and GZK-002 treatment at the doses 1 and 2 mg/kg on levels of monoamines and their metabolites in BALB/c mice brain were determined by HPLC. Neurochemical data demonstrated that an

Externí odkaz: https://doaj.org/article/914ecee0968d48a68f6126a699bf813d

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Akademický článek

The relationship between the content of the potential psychopharmacological agent cyclo-L-prolylglycine in the brain of experimental animals and its antihypoxic effect

Autor: V. P. Zherdev, S. S. Boyko, K. N. Kolyasnikova

Publikováno v: Фармакокинетика и Фармакодинамика, Vol 0, Iss 1, Pp 25-29 (2020)

In the study of strutural and intracellular distribution of cyclo-t-prolylglycine (CPG) in brain rats in experiments on mongrel white male rats, it was found that CPG determined more in the hippocampus and cerebral cortex with predominant localizatio

Externí odkaz: https://doaj.org/article/dd7b85a4066b425faa5a125fc1c13f9e

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Akademický článek

Neuroprotective properties of novel substituted glyprolines in vitro

Autor: T. A. Antipova, K. N. Kolyasnikova, Y. S. Volkova, P. I. Antipov, E. A. Kuznetsova, S. V. Nikolaev

Publikováno v: Фармакокинетика и Фармакодинамика, Vol 0, Iss 3, Pp 31-36 (2019)

Resume. Previously in the Zakusov Institute of Pharmacology the linear substituted glyproline GZK-111, N-phenylacetyl-glycyl-L-proline ethyl ester, which is capable to convert into the neuropeptide cyclo-prolylglycine (CPG) in biological media and di

Externí odkaz: https://doaj.org/article/b17cb99daa53436a9ff3ed2882996661

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Akademický článek

Neuroprotective effect of L-cycloprolylglycine on models neuronal cells damage in vitro

Autor: S. V. Nikolaev, I. O. Logvinov, P. I. Antipov, K. N. Kolyasnikova, T. A. Antipova

Publikováno v: Фармакокинетика и Фармакодинамика, Vol 0, Iss 3, Pp 26-29 (2017)

We have studied neuroprotective effect of L-cycloprolylglycine (L-CPG) in vitro experiments. It is shown that L-CPG has neuroprotective effect in the conditions an oxidative stress, glutamate and 6-hydroxydopamine toxicity.

Externí odkaz: https://doaj.org/article/8e9139a0618f4bd583e116700dffbe59

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Akademický článek

Effects of Hemantane upon the level of lipid peroxidation in brain in experimental parkinsonian syndrome

Autor: E. A. Ivanova, I. G. Kapitsa, N. N. Zolotov, E. A. Valdman, A. V. Nepoklonov, K. N. Kolyasnikova, T. A. Voronina

Publikováno v: Фармакокинетика и Фармакодинамика, Vol 0, Iss 3, Pp 9-12 (2016)

In two animaL modeLs of parkinsonian syndrome - induced by 1-methyL-4-phenyL-1,2,3,6-tetrahydropiridine (MPTP) in C57BL/6 mice and 6-hydroxidopamine (6-OHDA) in rats noveL antiparkinsonian drug hemantane was shown to reduce the increase of brain Leve

Externí odkaz: https://doaj.org/article/1a792802021e45d2a1e8e9ec8ebd5cd2

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