Zobrazeno 1 - 10
of 19
pro vyhledávání: '"K. N. Faber"'
Autor:
A Bourgonje, S Hu, R Gacesa, B H Jansen, J R Björk, A Bangma, I J Hidding, H M van Dullemen, M C Visschedijk, K N Faber, G Dijkstra, H J M Harmsen, E A M Festen, A Vich Vila, L M Spekhorst, R K Weersma
Publikováno v:
Journal of Crohn's and Colitis. 17:i113-i115
Background Host intestinal immune gene signatures and microbial dysregulations expose potential mechanisms in the pathogenesis of inflammatory bowel diseases (IBD). Profiling of mucosa-attached microbiota allows the understanding of locally present m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bb5d8c968544a4880ec20fa6f516c20
https://doi.org/10.1093/ecco-jcc/jjac190.0086
https://doi.org/10.1093/ecco-jcc/jjac190.0086
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208922 (2018)
IntroductionTNF-α-neutralizing antibodies, such as infliximab (IFX) and adalimumab (ADA), are effective in the treatment of inflammatory bowel diseases (IBD), but they are expensive and become ineffective when patients develop anti-IFX or anti-ADA a
Externí odkaz:
https://doaj.org/article/ee266d4620e84cd8b0bd9a322485b04a
Autor:
A R Bourgonje, S Andreu-Sánchez, T Vogl, S Hu, A Vich Vila, S Leviatan, A Kurilshikov, S Klompus, I N Kalka, H M van Dullemen, A Weinberger, M C Visschedijk, E A M Festen, K N Faber, C Wijmenga, G Dijkstra, E Segal, J Fu, A Zhernakova, R K Weersma
Publikováno v:
Journal of Crohn's and Colitis. 16:i100-i102
Background Patients with IBD show distinct antibody responses, particularly against microbiota. However, a comprehensive overview of the antibody epitope repertoire in IBD is lacking. Here, we characterized serum antibody responses in patients with I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2b883e72088e08e788ca6c92ae6ba47
https://doi.org/10.1093/ecco-jcc/jjab232.092
https://doi.org/10.1093/ecco-jcc/jjab232.092
Autor:
E A Mendieta Escalante, A Barrera-Vargas, J J Torres-Ruiz, F Merayo-Chalico, G Dijkstra, K N Faber, J K Yamamoto Furusho
Publikováno v:
Journal of Crohn's and Colitis. 17:i253-i254
Background Introduction: Neutrophils and neutrophil extracellular traps (NETs) play a significant role in the pathogenesis of ulcerative colitis (UC), a chronic and relapsing inflammatory disease of the colon. Low-density neutrophils (LDNs) are a rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9db8e161042b1a8b9849d86f8e3571d
https://doi.org/10.1093/ecco-jcc/jjac190.0220
https://doi.org/10.1093/ecco-jcc/jjac190.0220
Autor:
E A Mendieta Escalante, D Parada-Venegas, A Bourgonje, C Roozendaal, M Hermoso Ramello, K N Faber, G Dijkstra
Publikováno v:
Journal of Crohn's and Colitis. 17:i262-i263
Background The number of mucosal neutrophils, as well as the presence of neutrophil extracellular traps (NETs), correlate with disease activity in Ulcerative colitis (UC), an inflammatory bowel disease. Most (~80%) UC patients present atypical Anti-N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e737dd2fe465af60dc830dd65098064d
https://doi.org/10.1093/ecco-jcc/jjac190.0230
https://doi.org/10.1093/ecco-jcc/jjac190.0230
Autor:
A R Bourgonje, S Hu, L M Spekhorst, D V Zhernakova, A Vich Vila, Y Li, M D Voskuil, L A van Berkel, B Bley Folly, M Charrout, A Mahfouz, M J T Reinders, J I P van Heck, L A B Joosten, M C Visschedijk, H M van Dullemen, K N Faber, J N Samsom, E A M Festen, G Dijkstra, R K Weersma
Publikováno v:
Journal of Crohn's and Colitis. 15:S036-S039
Background Protein profiling in patients with inflammatory bowel diseases (IBD) for diagnostic and therapeutic purposes is underexplored. Assessment of interactions between genetics and the plasma proteome could lead to identification of novel diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c75c3cbe482a02ee26f2455b8df36c01
https://doi.org/10.1093/ecco-jcc/jjab075.038
https://doi.org/10.1093/ecco-jcc/jjab075.038
Autor:
C. Biel, O. Martinec, B. Sibering, K. van Summeren, A. M. A. Wessels, D. J. Touw, K. P. de Jong, V. E. de Meijer, K. N. Faber, J. P. ten Klooster, I. A. M. de Graaf, P. Olinga
Publikováno v:
Archives of toxicology. SPRINGER HEIDELBERG
Human Precision-cut intestinal slices (hPCIS) are used to study intestinal physiology, pathophysiology, drug efficacy, toxicology, kinetics, and metabolism. However, the use of this ex vivo model is restricted to approximately a 24 h timeframe becaus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f8a7c4dc07932af89a84584c0e77181
https://research.rug.nl/en/publications/21f731bd-9185-44ed-9500-f59c11281a4e
https://research.rug.nl/en/publications/21f731bd-9185-44ed-9500-f59c11281a4e
Autor:
C, Biel, O, Martinec, B, Sibering, K, van Summeren, A M A, Wessels, D J, Touw, K P, de Jong, V E, de Meijer, K N, Faber, J P Ten, Klooster, I A M, de Graaf, P, Olinga
Publikováno v:
Archives of toxicology. 96(6)
Human Precision-cut intestinal slices (hPCIS) are used to study intestinal physiology, pathophysiology, drug efficacy, toxicology, kinetics, and metabolism. However, the use of this ex vivo model is restricted to approximately a 24 h timeframe becaus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9bca54d85e7c59bb3fe14b7a550394d9
https://pubmed.ncbi.nlm.nih.gov/35428896
https://pubmed.ncbi.nlm.nih.gov/35428896
Autor:
M Sorokina Alexdóttir, A R Bourgonje, M A Karsdal, A C Bay-Jensen, M Pehrsson, R Loveikyte, H M van Dullemen, M C Visschedijk, E A M Festen, R K Weersma, K N Faber, G Dijkstra, M Joachim H
Publikováno v:
Journal of Crohn's and Colitis. 16:i468-i469
Background Crohn‘s disease (CD) is a form of inflammatory bowel disease characterized by high infiltration of immune cells into the intestinal tissue, resulting in increased proteolytic mediated extracellular matrix (ECM) remodeling. Disease manage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa21fa23c0149c10053422c2affc07dc
https://doi.org/10.1093/ecco-jcc/jjab232.636
https://doi.org/10.1093/ecco-jcc/jjab232.636
Autor:
A R Bourgonje, S J Wichers, S Hu, H M van Dullemen, M C Visschedijk, K N Faber, E A M Festen, G Dijkstra, J N Samsom, R K Weersma, L M Spekhorst
Publikováno v:
Journal of Crohn's and Colitis. 16:i284-i285
Background Fatigue is a common and clinically challenging symptom in patients with inflammatory bowel diseases (IBD). While fatigue occurs most often in patients with active disease, up to 50% of patients with quiescent disease still report significa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aad2642bb7292c2fe0acf1d00a6f0688
https://doi.org/10.1093/ecco-jcc/jjab232.364
https://doi.org/10.1093/ecco-jcc/jjab232.364