Robust and persistent B-cell responses following SARS-CoV-2 vaccine determine protection from SARS-CoV-2 infection

Autor: Joanne Byrne, Lili Gu, Alejandro Garcia-Leon, Colette Marie Gaillard, Gurvin Saini, Dana Alalwan, Julen Tomás-Cortázar, Grace Kenny, Sean Donohue, Bearach Reynolds, Tessa O’Gorman, Alan Landay, Peter Doran, Jannik Stemler, Philipp Koehler, Rebecca Jane Cox, Ole F. Olesen, Jean-Daniel Lelievre, Cathal O’Broin, Stefano Savinelli, Eoin R. Feeney, Jane A. O’Halloran, Aoife Cotter, Mary Horgan, Christine Kelly, Corrina Sadlier, Eoghan de Barra, Oliver A. Cornely, Virginie Gautier, Patrick WG Mallon, All Ireland Infectious Diseases cohort study and VACCELERATE consortium, A. Cotter, E. Muldoon, G. Sheehan, T. McGinty, J. S. Lambert, T. O’Gorman, C. Kelly, K. Leamy, J. Byrne, G. Kenny, K. McCann, R. McCann, C. O’Broin, S. Savinelli, J. O’Halloran, E. Feeney, P. W. G. Mallon, A. Garcia Leon, S. Miles, D. Alalwan, R. Negi, G. Saini, E. Moore, E. de Barra, S. McConkey, K. Hurley, B. Jacob, F. Lyons, M. Horgan, C. Sadlier, T. Bracken, B. Whelan, J Low, O Yousif, B. McNicholas, G. Courtney, C. O’Maoldomhnaigh, P. Gavin, Julia M. Neuhann, Ullrich Bethe, Sarah Heringer, Jon Salmanton-Garcı́a, Lea Tischmann, Arnd Cüppers, Jan Grothe, Antonio J. Carcas, Jesús Frías-Iniesta, Murat Akova, Alejandro Garcia Leon, Patrick Mallon, Riya Negi, Colette Gaillard, Christine Lammens, An Hotterbeekx, Katherine Loens, Surbhi Malhotra-Kumar, Herman Goossens, Samir Kumar-Singh, Franz König, Lusine Yeghiazaryan, Martin Posch

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

IntroductionA clear immune correlate of protection from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has not been defined. We explored antibody, B-cell, and T-cell responses to the third-dose vaccine and relationship to inci

Externí odkaz: https://doaj.org/article/1469edd2e8884d0ab79ea55f12a635fa

Meta-analysis of variation suggests that embracing variability improves both replicability and generalizability in preclinical research.

Autor: Takuji Usui, Malcolm R Macleod, Sarah K McCann, Alistair M Senior, Shinichi Nakagawa

Publikováno v: PLoS Biology, Vol 19, Iss 5, p e3001009 (2021)

The replicability of research results has been a cause of increasing concern to the scientific community. The long-held belief that experimental standardization begets replicability has also been recently challenged, with the observation that the red

Externí odkaz: https://doaj.org/article/55e9cee4ba764fb4bd6fc1f0811d49eb

Implementation characteristics of father‐inclusive interventions in low‐ and middle‐income countries: A systematic review

Autor: Joshua Jeong, Eileen F. Sullivan, Juliet K. McCann, Dana C. McCoy, Aisha K. Yousafzai

Publikováno v: Ann N Y Acad Sci

Although prior reviews have documented the effectiveness of engaging male caregivers in early childhood interventions, little is known about how these interventions have been designed and implemented to reach, engage, and support male caregivers in l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::776b6e762b2228fda523bbc2343c260c
https://doi.org/10.1111/nyas.14941

Animal models of chemotherapy-induced peripheral neuropathy: A machine-assisted systematic review and meta-analysis.

Autor: Gillian L Currie, Helena N Angel-Scott, Lesley Colvin, Fala Cramond, Kaitlyn Hair, Laila Khandoker, Jing Liao, Malcolm Macleod, Sarah K McCann, Rosie Morland, Nicki Sherratt, Robert Stewart, Ezgi Tanriver-Ayder, James Thomas, Qianying Wang, Rachel Wodarski, Ran Xiong, Andrew S C Rice, Emily S Sena

Publikováno v: PLoS Biology, Vol 17, Iss 5, p e3000243 (2019)

We report a systematic review and meta-analysis of research using animal models of chemotherapy-induced peripheral neuropathy (CIPN). We systematically searched 5 online databases in September 2012 and updated the search in November 2015 using machin

Externí odkaz: https://doaj.org/article/57aada0eb6ad449898cdc04781f480c0

Flexible, Front-Facing Luminescent Solar Concentrators Fabricated from Lumogen F Red 305 and Polydimethylsiloxane

Autor: Ian A. Carbone, Katelynn R. Frawley, Melissa K. McCann

Publikováno v: International Journal of Photoenergy, Vol 2019 (2019)

Luminescent solar concentrators (LSCs) fabricated with transparent host materials and fluorescent organic dyes are cost effective and versatile tools for solar power production. In this study, the first flexible, front-facing LSCs utilizing Lumogen F

Externí odkaz: https://doaj.org/article/1145f563da9349cd9daa59aaeb76362a