Zobrazeno 1 - 10
of 136
pro vyhledávání: '"K. Martikainen"'
Autor:
Mikael Laaksonen, Jaakko Rinne, Melissa Rahi, Jussi P. Posti, Ruut Laitio, Juri Kivelev, Ilkka Saarenpää, Dan Laukka, Juhana Frösen, Antti Ronkainen, Stepani Bendel, Jaakko Långsjö, Marika Ala-Peijari, Jani Saunavaara, Riitta Parkkola, Mikko Nyman, Ilkka K. Martikainen, Alex M. Dickens, Juha Rinne, Mika Valtonen, Teijo I. Saari, Timo Koivisto, Paula Bendel, Timo Roine, Antti Saraste, Tero Vahlberg, Juha Tanttari, Timo Laitio
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-17 (2023)
Abstract Background Aneurysmal subarachnoid hemorrhage (aSAH) is a neurological emergency, affecting a younger population than individuals experiencing an ischemic stroke; aSAH is associated with a high risk of mortality and permanent disability. The
Externí odkaz:
https://doaj.org/article/9d946299390741bfa6d617d14bb790b5
Autor:
Javier Ballester, Anne K. Baker, Ilkka K. Martikainen, Vincent Koppelmans, Jon-Kar Zubieta, Tiffany M. Love
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract µ-Opioid receptors (MOR) are a major target of endogenous and exogenous opioids, including opioid pain medications. The µ-opioid neurotransmitter system is heavily implicated in the pathophysiology of chronic pain and opioid use disorder a
Externí odkaz:
https://doaj.org/article/9e620463bb6041019c7ede6134518b4d
Akademický článek
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Autor:
I. K. Martikainen, Seppo Helisalmi, Semi Helin, Yawu Liu, Jarkko Johansson, Tiia Ngandu, Riitta Parkkola, Nina Kemppainen, Hilkka Soininen, Miia Kivipelto, Juha O. Rinne, Jarmo Teuho
Publikováno v:
American Journal of Neuroradiology. 40(1):80-85
BACKGROUND AND PURPOSE: The relationship between brain β-amyloid and regional atrophy is still incompletely understood in elderly individuals at risk of dementia. Here, we studied the associations between brain β-amyloid load and regional GM and WM
Autor:
Marcos F DosSantos, Ilkka K Martikainen, Thiago D Nascimento, Tiffany M Love, Misty D DeBoer, Heidi M Schambra, Marom Bikson, Jon-Kar Zubieta, Alexandre F DaSilva
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102350 (2014)
Transcranial Direct Current Stimulation (tDCS) is a method of non-invasive brain stimulation that has been frequently used in experimental and clinical pain studies. However, the molecular mechanisms underlying tDCS-mediated pain control, and most im
Externí odkaz:
https://doaj.org/article/3e6ad0367acb4c4987cfb4c5a77b8b17
Publikováno v:
European Journal of Pharmacology. 834:337-345
Here we review the literature assessing the roles of the brain dopaminergic and serotonergic systems in the modulation of pain as revealed by in vivo human studies using positron emission tomography. In healthy subjects, dopamine D-2/D-3 receptor ava
Autor:
Tero Taiminen, Nora Hagelberg, Salla Lamusuo, Jussi Hirvonen, Riitta Parkkola, Satu K. Jääskeläinen, Semi Helin, Arja Virtanen, Ilkka K. Martikainen, Pauliina Lindholm, Antti Pertovaara, Jarmo Hietala
Publikováno v:
European Journal of Pain. 21:1505-1515
Background Repetitive transcranial magnetic stimulation (rTMS) at M1/S1 cortex has been shown to alleviate neuropathic pain. Objectives To investigate the possible neurobiological correlates of cortical neurostimulation for the pain relief. Methods W
Autor:
Jon Kar Zubieta, Tiffany M. Love, Chelsea M. Cummiford, Christian S. Stohler, Marta Peciña, Carmen R. Green, Ilkka K. Martikainen, Emily B. Nuechterlein
Publikováno v:
Journal of Neuroscience. 35:9957-9965
Back pain is common in the general population, but only a subgroup of back pain patients develops a disabling chronic pain state. The reasons for this are incompletely understood, but recent evidence implies that both preexisting and pain-related var
Autor:
Misty DeBoer, Alexandre F. DaSilva, Yolanda R. Smith, Tiffany M. Love, Jon Kar Zubieta, Eric Maslowski, Ilkka K. Martikainen, Thiago D. Nascimento, Sarah K. Lucas, Robert A. Koeppe, Marcos F. DosSantos, Hendrik van Holsbeeck
Publikováno v:
Annals of Clinical and Translational Neurology
We investigated in vivo the allodynic response of the central μ-opioid system during spontaneous migraine headaches, following a sustained pain threshold challenge on the trigeminal ophthalmic region. Six migraineurs were scanned during the ictal an
Autor:
Alexandre F. DaSilva, Hendrik van Holsbeeck, Yolanda R. Smith, Tiffany M. Love, Marcos F. DosSantos, Sarah K. Lucas, Jon Kar Zubieta, Thiago D. Nascimento, Misty DeBoer, Eric Maslowski, Ilkka K. Martikainen, Robert A. Koeppe
Publikováno v:
Annals of Clinical and Translational Neurology. 1:439-444
We evaluated in vivo the μ-opioid system during spontaneous episodic migraine headaches. Seven patients were scanned at different phases of their migraine using positron emission tomography with the selective μ-opioid receptor (μOR) radiotracer [1