Zobrazeno 1 - 10
of 29
pro vyhledávání: '"K. M. D. La Perle"'
Autor:
Dawn S. Chandler, A K Goodwin, Bridget Sanford, P Boyaka, Thomas W. Bebee, K. M. D. La Perle, E Matsa, H Steiner, Daniel F. Comiskey, M Montes, Aixa S. Tapia-Santos, Jessica L. Grieves, Aishwarya G. Jacob
Publikováno v:
Oncogene
Alternative splicing of the oncogene murine double minute 2 (MDM2) is induced in response to genotoxic stress. MDM2-ALT1, the major splice variant generated, is known to activate the p53 pathway and impede full-length MDM2's negative regulation of p5
Autor:
Sara L. Sinicropi-Yao, Muhammed Murtaza, David P. Carbone, William P.D. Hendricks, Timothy G. Whitsett, Tania Contente-Cuomo, Victoria Zismann, Shukmei Wong, Winnie S. Liang, Michael J. Koenig, Joseph M. Amann, Alexandra Nazareno, Jeffrey M. Trent, K. M. D. La Perle, Nieves Perdigones, I. Diala, Alshad S. Lalani, Salvatore Facista, Gwendolen Lorch, L. Eli
Publikováno v:
Journal of Thoracic Oncology. 14:S832-S833
Publikováno v:
Veterinary Pathology. 49:642-647
This report describes a spontaneous prostate fibromyxoid sarcoma with smooth muscle differentiation in an approximately 136-week-old intact male F344xBNF1 rat on a diet study for 2 weeks. At necropsy, the prostate was markedly distorted and enlarged
Autor:
K. M. D. La Perle, Claudia Foray, Eliana Rulli, Valerio Embrione, Vincenzo Coppola, Anna Tessari, Matteo Fassan, Kareesma Parbhoo, Meghan Pawlikowski, Massimo Broggini, Joseph M. Amann, Monica Ganzinelli, Dario Palmieri, Alessandra Fabbri, M.C. Garassino, David P. Carbone, Carlo M. Croce
Publikováno v:
Journal of Thoracic Oncology. 12:S2123-S2124
Autor:
Vasyl Vasko, Motoyasu Saji, K. Narahara, Kyle Porter, C. Lu, David Jarjoura, Sheue-yann Cheng, Matthew D. Ringel, K. M. D. La Perle, Samantha K McCarty
Publikováno v:
Oncogene
Akt activation is common in progressive thyroid cancer. In breast cancer, Akt1 induces primary cancer growth, but is reported to inhibit metastasis in vivo in several model systems. In contrast, clinical and in vitro studies suggest a metastasis-prom
Autor:
A. McIntyre, K. M. D. La Perle
Publikováno v:
Veterinary Pathology. 44:249-252
Hermaphroditism was diagnosed in three, 6-month-old, male, chimeric mice generated by microinjection of 129/Ola XY recombinant embryonic stem cells into unsexed C57BL/6 blastocysts. Grossly, mice Nos. 1 and 2 had perigenital masses and hydrometra. Al
Autor:
Bonnie Williams, W. Yang, Je-Yoel Cho, Tara L.F. Buckwalter, H. N. Nagaraja, Richard T. Kloos, Sissy M. Jhiang, K. M. D. La Perle, Rodney V. Pozderac, Daniel H. Y. Shen, Rolf F. Barth, George H. Hinkle
Publikováno v:
Gene Therapy. 9:1139-1145
Radioactive iodide uptake (RAIU) in thyroid follicular epithelial cells, mediated by the sodium iodide symporter (NIS), is the first rate-limiting step in iodide accumulation which provides a mechanism for effective radioiodide treatment for patients
Publikováno v:
Veterinary Pathology. 46:1245-1247
Phenotypic analysis of genetically engineered mice and detailed evaluations of mouse models of disease have become increasingly important areas of expertise for the veterinary pathologist. Over the last few years, several articles, editorials, and le
Publikováno v:
Journal of Comparative Pathology. 120:211-217
Hodgkin's-like lymphoma involving the lung, mediastinum, liver, kidneys and mesenteric lymph nodes was diagnosed in a ferret. The diagnosis was based on the presence of an admixture of CD3+ small lymphocytes with smaller numbers of macrophages, eosin
Autor:
Lianbo Yu, Parmeet Kaur Manchanda, Audrey A. Lee, Lawrence S. Kirschner, Daphne R. Pringle, K. M. D. La Perle, Georgette N. Jones, Manchao Zhang
Publikováno v:
Oncogene
Schwannomas are peripheral nerve sheath tumors that often occur in the setting of an inherited tumor predisposition syndrome, including neurofibromatosis types 1 (NF1) and 2 (NF2), familial schwannomatosis and Carney complex. Loss of the NF2 tumor su