Zobrazeno 1 - 10
of 17
pro vyhledávání: '"K. M. Connolly"'
Publikováno v:
Semiconductor Science and Technology. 11:1552-1557
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5ea3038a874201a4595dc7260e05fd4
https://doi.org/10.1088/0268-1242/11/11s/017
https://doi.org/10.1088/0268-1242/11/11s/017
Publikováno v:
Cytokine. 5:298-304
The primary purpose of this study was to determine whether local levels of tumor necrosis factor (TNF) were elevated in chronically inflamed joints in rats with adjuvant-induced arthritis (AA). We also wished to develop methodology for the quantitati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab6ed6e4d80a1fb01d424f06e8ccc29b
https://doi.org/10.1016/1043-4666(93)90060-i
https://doi.org/10.1016/1043-4666(93)90060-i
Publikováno v:
Journal of biomolecular NMR. 14(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3515574656d0d21cf3e78ee744976a6e
https://pubmed.ncbi.nlm.nih.gov/10382314
https://pubmed.ncbi.nlm.nih.gov/10382314
Publikováno v:
Nature structural biology. 6(4)
The integrase protein catalyzes the excision and integration of the Tn916 conjugative transposon, a promiscuous genetic element that spreads antibiotic resistance in pathogenic bacteria. The solution structure of the N-terminal domain of the Tn916 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::433ae950a3532b6257842ba166035b73
https://pubmed.ncbi.nlm.nih.gov/10201406
https://pubmed.ncbi.nlm.nih.gov/10201406
Autor:
L, Sekut, B, Han, P, Baer, M W, Verghese, R, Silverstein, L, Clifton, S, Dennis, M J, Numerick, K M, Connolly
Publikováno v:
Laboratory animal science. 45(6)
Using tumor necrosis factor (TNF) inhibition in dog blood as a measure of efficacy, and canine emesis as a measure of toxicity, we were able to assign a therapeutic index to rolipram, a prototypic anti-inflammatory compound. Because both assays were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::841dfcd327c2bd51420aa7c6c5123440
https://pubmed.ncbi.nlm.nih.gov/8746524
https://pubmed.ncbi.nlm.nih.gov/8746524
SUMMARY Elevation of intracellular cAMP levels has been shown previously to inhibit cytokine secretion by various cell types in vitro. Since salmeterol is a β2-agonist which activates adenylate cyclase, its ability to inhibit cytokine production was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6346319987433d05566e15dcd43ec88
https://europepmc.org/articles/PMC1534196/
https://europepmc.org/articles/PMC1534196/
Autor:
J. A. Menius, L. S. Noel, D P Yarnall, L. Sekut, K M Connolly, M. F. Brackeen, R. L. Clark, Stephen A. Stimpson, R. Bateman-Fite
SUMMARY Inhibitors of cyclic nucleotide phosphodiesterases are known to suppress lipopolysaccharide (LPS)-induced tumour necrosis factor-alpha (TNF-α) production in vitro in human monocytes. The most potent of these have selectivity for type IV PDEs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd3dc2c3ef7a792cac994fadbfa7e1f0
Publikováno v:
The Journal of laboratory and clinical medicine. 124(6)
Elevated tumor necrosis factor (TNF) levels have been reported in various models of acute and chronic inflammation and used by many investigators to determine the stage of disease and effectiveness of treatment. Because of the documented involvement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4817b5e54d58a9a7f4a2bbe4e0d774df
https://pubmed.ncbi.nlm.nih.gov/7798795
https://pubmed.ncbi.nlm.nih.gov/7798795
Publikováno v:
Agents and Actions. 25:164-170
The purpose of the study was to determine if danazol was efficacious in the treatment of lupus MRL/MpJ (lpr) mice, as measured by longevity, proteinuria and serum amyloid protein (SAP) levels. Danazol, administered at an oral dose of 100 mg/kg, signi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41a9aad0a66e87f001cc5438db9c1996
https://doi.org/10.1007/bf01969108
https://doi.org/10.1007/bf01969108
Autor:
K M, Connolly, K D, Elgert
Publikováno v:
Journal of the Reticuloendothelial Society. 28(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6adafa738879f43ed08ecd663f0d2a79
https://pubmed.ncbi.nlm.nih.gov/6446602
https://pubmed.ncbi.nlm.nih.gov/6446602