Zobrazeno 1 - 10
of 17
pro vyhledávání: '"K. M. Burnysheva"'
Autor:
Vladimir A. Mitkevich, Valentina A. Lakunina, A. A. Makarov, K. M. Burnysheva, Irina Yu. Petrushanko
Publikováno v:
Doklady Biochemistry and Biophysics. 473:114-117
We have shown that the inhibition of Na,K-ATPase during its long-term incubation with amyloid beta (Aβ42), an Alzheimer’s disease protein, is caused by the change in the thiol redox status of cells leading to induction of glutathionylation α-subu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2814fc1a0814b756f2f604bf777304c5
https://doi.org/10.1134/s1607672917020077
https://doi.org/10.1134/s1607672917020077
Autor:
Vladimir A. Mitkevich, A. A. Makarov, Valentina A. Lakunina, Irina Yu. Petrushanko, K. M. Burnysheva
Publikováno v:
Molecular Biology. 51:148-154
Na,K-ATPase maintains sodium and potassium homeostasis. It is the only known receptor for cardiotonic steroids such as ouabain. Binding of ouabain to Na,K-ATPase leads to the activation of Src kinase and the subsequent initiation of intracellular sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39d696295abd708bba94816be0bc4fbe
https://doi.org/10.1134/s0026893317010101
https://doi.org/10.1134/s0026893317010101
Autor:
T. M. Astakhova, K. M. Burnysheva, Alexandra A. Kulikova, A. V. Morozov, Vadim L. Karpov, N. P. Sharova, Alexander A. Makarov, Vladimir A. Mitkevich, Pavel A. Erokhov, Alexei A. Adzhubei, M B Evgen'ev
Publikováno v:
Journal of Alzheimer's Disease. 54:763-776
Accumulation of amyloid-β (Aβ) in neurons accompanies Alzheimer's disease progression. In the cytoplasm Aβ influences activity of proteasomes, the multisubunit protein complexes that hydrolyze the majority of intracellular proteins. However, the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35398c312951595ce8ff7683c4e0e7b8
https://doi.org/10.3233/jad-160491
https://doi.org/10.3233/jad-160491
Publikováno v:
Molecular Biology. 50:762-767
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6dea06857a9398543a17dad64857e23
https://doi.org/10.1134/s0026893316050034
https://doi.org/10.1134/s0026893316050034
Autor:
Vladimir S. Prassolov, Vladimir A. Mitkevich, P. V. Spirin, Alexander A. Makarov, I. Yu. Petrushanko, K. M. Burnysheva
Publikováno v:
Molecular Biology. 50:302-306
Bacterial ribonuclease binase is a potential anticancer agent. In the present study, we have determined the toxic effect of binase towards cell lines of T-cell acute lymphoblastic leukemia Jurkat and CEMss. We have shown that binase induces apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07257ced328a568facad98093dcb6f0c
https://doi.org/10.1134/s0026893316020035
https://doi.org/10.1134/s0026893316020035
Рибонуклеаза биназа вызывает гибель клеток острого Т-лимфобластного лейкоза, индуцируя в них апоптоз
Autor:
I. Yu. Petrushanko, Vladimir S. Prassolov, A. A. Makarov, K. M. Burnysheva, Vladimir A. Mitkevich, P. V. Spirin
Publikováno v:
Молекулярная биология. 50:347-352
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6c1f2cf69b18237ca16b91f8ead3f4a
https://doi.org/10.7868/s0026898416020038
https://doi.org/10.7868/s0026898416020038
Autor:
Vladimir A. Mitkevich, Yuri M. Poluektov, Irina Yu. Petrushanko, Alexander A. Makarov, Anastasia A. Anashkina, Valentina A. Lakunina, K. M. Burnysheva
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2016 (2016)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Many viruses induce oxidative stress and cause S-glutathionylation of Cys residues of the host and viral proteins. Changes in cell functioning during viral infection may be associated with glutathionylation of a number of key proteins including Na,K-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fccbe6193a10fd2820e2a00c05e716a
https://doi.org/10.1155/2016/9092328
https://doi.org/10.1155/2016/9092328
Autor:
Evgeny P. Barykin, K. M. Burnysheva, Vladimir A. Mitkevich, I. Yu. Petrushanko, Alexander A. Makarov
Publikováno v:
Молекулярная биология. 50:863-869
The generation of amyloid β (Aβ) toxic oligomers during the formation of senile plaques and amyloid fibrils is thought to play a central role in the onset and progression of Alzheimer's disease. Aβ production is a physiological process, but the fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::711b2806256a7effdc6f53f0affd2379
https://doi.org/10.7868/s0026898416050037
https://doi.org/10.7868/s0026898416050037
Autor:
Irina Yu. Petrushanko, Vladimir A. Mitkevich, K. M. Burnysheva, Alexey A. Schulga, Alexei A. Adzhubei, Peter M. Chumakov, Alexander A. Makarov
Publikováno v:
Oncotarget
In this study, we determined whether binase, a ribonuclease from Bacillus pumilus, increases interferon sensitivity and apoptosis in SiHa cervical cancer cells infected with high-risk human papilloma virus (HPV) strain 16. Binase treatment increased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edb20ebb0fd9724b130cf93e32ab65b7
https://pubmed.ncbi.nlm.nih.gov/29069817
https://pubmed.ncbi.nlm.nih.gov/29069817
Autor:
Nickolai A. Tchurikov, Vladimir A. Mitkevich, Alexander A. Makarov, Olga V. Kretova, Olga N. Ilinskaya, Irina Yu-U. Petrushanko, Dmitry V. Sosin, Olga V. Simonenko, K. M. Burnysheva
Publikováno v:
Biochimie. 95:1344-1349
Cytotoxic exogenous RNases triggering apoptotic response in malignant cells have potential as anticancer drugs; surprisingly, detailed characterization of the RNase-induced apoptosis has not been conducted so far. Here we show that a cytotoxic RNase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd63ae2be80ebb41295b7d3d0c79b8a3
https://doi.org/10.1016/j.biochi.2013.02.016
https://doi.org/10.1016/j.biochi.2013.02.016