Zobrazeno 1 - 10
of 139
pro vyhledávání: '"K. Lewinski"'
Autor:
Paula C. Soto, Valeri H. Terry, Mary K. Lewinski, Savitha Deshmukh, Nadejda Beliakova-Bethell, Celsa A. Spina
Publikováno v:
PLoS ONE, Vol 17, Iss 7 (2022)
Latently infected CD4 T cells form a stable reservoir of HIV that leads to life-long viral persistence; the mechanisms involved in establishment of this latency are not well understood. Three scenarios have been proposed: 1) an activated, proliferati
Externí odkaz:
https://doaj.org/article/fe5b5db34a014adf9a241c5807d9d15a
Autor:
Sang Ho Park, Haley Siddiqi, Daniela V Castro, Anna A De Angelis, Aaron L Oom, Charlotte A Stoneham, Mary K Lewinski, Alex E Clark, Ben A Croker, Aaron F Carlin, John Guatelli, Stanley J Opella
Publikováno v:
PLoS Pathogens, Vol 17, Iss 5, p e1009519 (2021)
SARS-CoV-2 is the novel coronavirus that is the causative agent of COVID-19, a sometimes-lethal respiratory infection responsible for a world-wide pandemic. The envelope (E) protein, one of four structural proteins encoded in the viral genome, is a 7
Externí odkaz:
https://doaj.org/article/7c6420860ea3475c9217299c1fbe66ce
Autor:
K Aurelia Ball, Jeffrey R Johnson, Mary K Lewinski, John Guatelli, Erik Verschueren, Nevan J Krogan, Matthew P Jacobson
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 6, p e1004898 (2016)
Growing evidence supports other regulatory roles for protein ubiquitination in addition to serving as a tag for proteasomal degradation. In contrast to other common post-translational modifications, such as phosphorylation, little is known about how
Externí odkaz:
https://doaj.org/article/0717798c289443a780f4cc59710b278b
Autor:
Paula C. Soto, Valeri H. Terry, Mary K. Lewinski, Savitha Deshmukh, Nadejda Beliakova-Bethell, Celsa A. Spina
Publikováno v:
PloS one, vol 17, iss 7
Latently infected CD4 T cells form a stable reservoir of HIV that leads to life-long viral persistence; the mechanisms involved in establishment of this latency are not well understood. Three scenarios have been proposed: 1) an activated, proliferati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cac55bd3191b025e27d53d30ad87c8b4
https://pubmed.ncbi.nlm.nih.gov/35895672
https://pubmed.ncbi.nlm.nih.gov/35895672
Autor:
Mary K. Lewinski, John C. Guatelli, Aaron L. Oom, Charlotte A. Stoneham, Daniela V. Castro, Haley Siddiqi, Ben A. Croker, Stanley J. Opella, Sang Ho Park, Alex E. Clark, Aaron F. Carlin, Anna A. De Angelis
Publikováno v:
PLoS pathogens, vol 17, iss 5
PLoS Pathogens, Vol 17, Iss 5, p e1009519 (2021)
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 5, p e1009519 (2021)
PLoS Pathogens
SARS-CoV-2 is the novel coronavirus that is the causative agent of COVID-19, a sometimes-lethal respiratory infection responsible for a world-wide pandemic. The envelope (E) protein, one of four structural proteins encoded in the viral genome, is a 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c20489ebca7cc3c7699c09635ede84
https://escholarship.org/uc/item/8jk636qf
https://escholarship.org/uc/item/8jk636qf
Autor:
John C. Guatelli, Charlotte A. Stoneham, Mary K. Lewinski, Aaron L. Oom, Alicia L. Richards, Km Shams-Ud-Doha, Jacob M. Wozniak, David Gonzalez, Nevan J. Krogan
As systems biology approaches to virology have become more tractable, highly studied viruses such as HIV can now be analyzed in new, unbiased ways, including spatial proteomics. We employed here a differential centrifugation protocol to fractionate J
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b43eae77d0170f30a3655183978aaf16
https://doi.org/10.1101/2021.03.17.435902
https://doi.org/10.1101/2021.03.17.435902
Autor:
Aaron L. Oom, Charlotte A. Stoneham, Mary K. Lewinski, Alicia Richards, Jacob M. Wozniak, Km Shams-Ud-Doha, David J. Gonzalez, Nevan J. Krogan, John Guatelli
Publikováno v:
Molecular & cellular proteomics : MCP, vol 21, iss 3
As systems biology approaches to virology have become more tractable, highly studied viruses such as HIV can now be analyzed in new unbiased ways, including spatial proteomics. We employed here a differential centrifugation protocol to fractionate Ju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1174430a51d17eef41ba136eae4f28be
https://pubmed.ncbi.nlm.nih.gov/35017099
https://pubmed.ncbi.nlm.nih.gov/35017099
Autor:
Christopher Churas, Lisa Miorin, Dexter Pratt, Anshu P. Gounder, Aaron L. Oom, Laura Martin-Sancho, Sumit K. Chanda, Judd F. Hultquist, Sophie Liu, Courtney Nguyen, Max W. Chang, Ariel Rodriguez-Frandsen, Trey Ideker, Alan M. O’Neill, Matthew Urbanowski, Yuan Pu, Megan L. Shaw, Sara Brin Rosenthal, John C. Guatelli, Paul D. De Jesus, Charlotte A. Stoneham, Christopher Benner, Mary K. Lewinski, Matthew B. Frieman, Lars Pache, Adolfo García-Sastre, Xin Yin
Publikováno v:
bioRxiv
A deficient interferon response to SARS-CoV-2 infection has been implicated as a determinant of severe COVID-19. To identify the molecular effectors that govern interferon control of SARS-CoV-2 infection, we conducted a large-scale gain-of-function a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bdb27efac76461cbaf3aeed7ee78337
https://europepmc.org/articles/PMC7536870/
https://europepmc.org/articles/PMC7536870/
Autor:
Mary K Lewinski, Masahiro Yamashita, Michael Emerman, Angela Ciuffi, Heather Marshall, Gregory Crawford, Francis Collins, Paul Shinn, Jeremy Leipzig, Sridhar Hannenhalli, Charles C Berry, Joseph R Ecker, Frederic D Bushman
Publikováno v:
PLoS Pathogens, Vol 2, Iss 6, p e60 (2006)
Retroviruses differ in their preferences for sites for viral DNA integration in the chromosomes of infected cells. Human immunodeficiency virus (HIV) integrates preferentially within active transcription units, whereas murine leukemia virus (MLV) int
Externí odkaz:
https://doaj.org/article/085421e974b14733afd1f0c13871433f
Autor:
Trey Ideker, Megan L. Shaw, Sara Brin Rosenthal, Matthew Urbanowski, Sumit K. Chanda, Chunxiang Wu, Thomas J. Hope, Yong Xiong, Charlotte A. Stoneham, Matthew B. Frieman, Aaron L. Oom, John C. Guatelli, Dexter Pratt, Sophie Liu, Christopher Churas, Courtney Nguyen, Anshu P. Gounder, Mary K. Lewinski, Lisa Miorin, Adolfo García-Sastre, Mark E. Becker, Stuart Weston, Yuan Pu, Alan M. O’Neill, Max W. Chang, Laura Martin-Sancho, Christopher Benner, Fan Zheng, Heather M. Curry, Paul D. De Jesus, Judd F. Hultquist, Ariel Rodriguez-Frandsen, Xin Yin, Lars Pache
Publikováno v:
Molecular cell, vol 81, iss 12
Molecular Cell
Molecular Cell
A deficient interferon (IFN) response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been implicated as a determinant of severe coronavirus disease 2019 (COVID-19). To identify the molecular effectors that govern IFN co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb9bcf12fce94be23d569fee1692ee0
https://doi.org/10.1016/j.molcel.2021.04.008
https://doi.org/10.1016/j.molcel.2021.04.008