Zobrazeno 1 - 10
of 143
pro vyhledávání: '"K. Lasseter"'
Akademický článek
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Autor:
S Purohit, K Lasseter, Amit Gandhi, Derry C. Roopenian, Robert George Edward Holgate, Jonathan J. Hubbard, J E Humphries, L E Stolz, Jan Terje Andersen, Michal Pyzik, Atiya Mahmood, D de Graaf, Susan D. Jones, Arron Hearn, Alan J. Bitonti, J S Graydon, Richard S. Blumberg, K Kacena, Laurence J. Blumberg, Gregory J. Christianson, B Del Tito, L B Pearce, J. Cheung
Publikováno v:
Science Advances
Therapeutic blockade of FcRn in humans decreases IgG and IgG immune complex levels with the attendant immunologic implications.
The neonatal crystallizable fragment receptor (FcRn) functions as an intracellular protection receptor for immunoglob
The neonatal crystallizable fragment receptor (FcRn) functions as an intracellular protection receptor for immunoglob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7956be3e71940724cce8ce3634ea7a40
http://hdl.handle.net/10852/76135
http://hdl.handle.net/10852/76135
Autor:
M. Willett, Netanya S. Utay, K. Lasseter, P. F. Smith, W. Chang, M. Gottwald, Anoma Somasunderam, E. Lefebvre
Publikováno v:
Clinical and Translational Science
Cenicriviroc, a dual CCR2/CCR5 antagonist, is being evaluated for treatment of nonalcoholic steatohepatitis and liver fibrosis (CENTAUR; NCT02217475). As it is metabolized by the liver, cenicriviroc was investigated in hepatic-impaired participants f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c1b94d806f3fe8a00fdbb1020a565c0
https://doi.org/10.1111/cts.12397
https://doi.org/10.1111/cts.12397
Autor:
Dermot Walsh, Ann E. Pulver, Ami Citri, Virginia K. Lasseter, Dimitris Dikeos, M. Jay, Michael John Owen, Wolfgang Maier, Jacques Mallet, Jianxin Shi, Nadine Norton, Hakon Hakonarson, Claudine Laurent, Sibylle G. Schwab, David Cohen, Stephan Ripke, Cynthia Gao, Jubao Duan, Kai Wang, Alan R. Sanders, Bernard Lerer, Peter Holmans, Dieter B. Wildenauer, Kenneth S. Kendler, Nigel Williams, Deborah A. Nertney, Stephanie Godard-Bauché, George N. Papadimitriou, Madeline Alexander, Dominique Campion, Brien P. Riley, Brandon Wormley, Douglas F. Levinson, Anthony O'Neill, Margot Albus, Gerald Nestadt, Ayman H. Fanous, Pablo V. Gejman, Frank Dudbridge, Mark Hansen, Jeremy M. Silverman, Sang Oh, Nan Zhang, Michael Conlon O'Donovan, Peter Eichhammer, Bryan J. Mowry
Publikováno v:
American Journal of Psychiatry
OBJECTIVE: The authors used a genome-wide association study (GWAS) of multiply affected families to investigate the association of schizophrenia to common single-nucleotide polymorphisms (SNPs) and rare copy number variants (CNVs). METHOD: The family
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::538ab8c99a114e239734bb00ae29d506
https://doi.org/10.1176/appi.ajp.2012.11091423
https://doi.org/10.1176/appi.ajp.2012.11091423
Autor:
Kung Yee Liang, David Valle, Dimitri Avramopoulos, Ingo Ruczinski, Qing Li, Thomas A. Louis, M. Daniele Fallin, John A. McGrath, Ann E. Pulver, Virginia K. Lasseter, Paula S. Wolyniec
Publikováno v:
Genetic Epidemiology. 34:396-406
Schizophrenia (SZ) is a heritable and complex psychiatric disorder with an estimated worldwide prevalence of about 1%. Research on the risk factors for SZ has thus far yielded few clues to causes, but has pointed to a heterogeneous etiology that like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3300161777c31ce61dd2595c5acc203
https://doi.org/10.1002/gepi.20488
https://doi.org/10.1002/gepi.20488
Publikováno v:
The Journal of Pain. 19:S74
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98798308c6784025e120e51b26706606
https://doi.org/10.1016/j.jpain.2017.12.168
https://doi.org/10.1016/j.jpain.2017.12.168
Autor:
John A. McGrath, M. D. Fallin, A. E. Pulver, Virginia K. Lasseter, Jennifer G. Mulle, Paula S. Wolyniec
Publikováno v:
Molecular Psychiatry. 12:367-375
Parent-of-origin effects have been implicated as mediators of genetic susceptibility for a number of complex disease phenotypes, including bipolar disorder. Specifically, evidence for linkage on chromosome 18 is modified when allelic parent-of-origin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2134eb558a9639be304493aec1ade8ae
https://doi.org/10.1038/sj.mp.4001916
https://doi.org/10.1038/sj.mp.4001916
Autor:
Ann E. Pulver, David Valle, Paula S. Wolyniec, Virginia K. Lasseter, John A. McGrath, Kung Yee Liang, M. Daniele Fallin, Gerald Nestadt
Publikováno v:
The American Journal of Human Genetics. 75(2):204-219
The relatively short history of linkage studies in bipolar disorders (BPs) has produced inconsistent findings. Implicated regions have been large, with reduced levels of significance and modest effect sizes. Both phenotypic and genetic heterogeneity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b717e7d31399cd27eda4414a42e57fe9
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Autor:
Virginia K. Lasseter, Y F Chiu, Paula S. Wolyniec, Karen Swartz, A. E. Pulver, Mary H. Thornquist, John A. McGrath, Gerald Nestadt, Kung-Yee Liang
Publikováno v:
Molecular Psychiatry. 7:658-664
Information from multiple genome scans and collaborative efforts suggests that schizophrenia is a heterogeneous, complex disorder with polygenic and environmental antecedents. In a previous paper we demonstrated that stratification of families on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::015123427804279e0e4c3f1938ee1cd8
https://doi.org/10.1038/sj.mp.4001045
https://doi.org/10.1038/sj.mp.4001045