Zobrazeno 1 - 10
of 12
pro vyhledávání: '"K. L. Schey"'
Autor:
G. Guo, M. Papanicolaou, N. J. Demarais, Z. Wang, K. L. Schey, P. Timpson, T. R. Cox, A. C. Grey
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
MALDI-mass spectrometry imaging (MSI) can reveal the distribution of proteins in tissues but tools for protein identification and annotation are sparse. Here, the authors develop an open-source bioinformatic workflow for false discovery rate-controll
Externí odkaz:
https://doaj.org/article/9f16ad7314d849e8abab580be63964d9
Publikováno v:
Photochemistry and photobiology. 74(5)
The tryptophan metabolite, xanthurenic acid (Xan), is produced through a transamination reaction in high concentrations in human lenses with age and has been isolated from aged human cataractous lenses. It has appreciable absorption between 300 and 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a8e2215a39529d1c13c28a78d17ad509
https://pubmed.ncbi.nlm.nih.gov/11723804
https://pubmed.ncbi.nlm.nih.gov/11723804
Publikováno v:
Photochemistry and photobiology. 72(2)
Hypericin is the active ingredient in the over the counter antidepressant medication St. John's Wort. Hypericin produces singlet oxygen and other excited state intermediates that indicate it should be a very efficient phototoxic agent in the eye. Fur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::63edc5d763217c176c2d4603204b5b63
https://pubmed.ncbi.nlm.nih.gov/10946573
https://pubmed.ncbi.nlm.nih.gov/10946573
Publikováno v:
Investigative ophthalmologyvisual science. 41(1)
To determine the primary covalent structure of human lens major intrinsic protein (MIP) in lenses of varying age.MIP was isolated from single human lenses of various ages (7- 86 years) by homogenization of the lenses, followed by centrifugation and u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::234c140706c0d6b43b24d9010bfddabf
https://pubmed.ncbi.nlm.nih.gov/10634618
https://pubmed.ncbi.nlm.nih.gov/10634618
Publikováno v:
Investigative ophthalmologyvisual science. 40(3)
To identify modifications to rat lens major intrinsic protein (MIP) isolated from selenite-induced cataract and to determine whether m-calpain (EC 3.4.22.17) is responsible for cleavage of MIP during cataractogenesis.Cataracts were induced in rats by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::10b5049942c133d3b675c3dc5e878bd6
https://pubmed.ncbi.nlm.nih.gov/10067969
https://pubmed.ncbi.nlm.nih.gov/10067969
Publikováno v:
The Journal of biological chemistry. 273(50)
Go is the major G protein in bovine brain, with at least three isoforms, GoA, GoB, and GoC. Whereas alphaoA and alphaoB arise from a single Goalpha gene as alternatively spliced mRNAs, alphaoA and alphaoC are thought to differ by covalent modificatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d5e86e9d0a04a57f0175bc176ca8e703
https://pubmed.ncbi.nlm.nih.gov/9837880
https://pubmed.ncbi.nlm.nih.gov/9837880
Publikováno v:
Investigative ophthalmologyvisual science. 38(12)
To determine the complete primary structure, including posttranslational modifications, of bovine lens major intrinsic protein (MIP) using a recently developed combination of liquid chromatography and mass spectrometry.The MIP was isolated from bovin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::adbbe86eca7d959c52942dc8a3a0fa56
https://pubmed.ncbi.nlm.nih.gov/9375569
https://pubmed.ncbi.nlm.nih.gov/9375569
Autor:
K L, Schey
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 61
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::72e01d2448beec7e3d5075f6538707ca
https://pubmed.ncbi.nlm.nih.gov/8930876
https://pubmed.ncbi.nlm.nih.gov/8930876
Autor:
M D, Wilcox, K L, Schey, J, Dingus, N D, Mehta, B S, Tatum, M, Halushka, J W, Finch, J D, Hildebrandt
Publikováno v:
The Journal of biological chemistry. 269(17)
The diversity of the gamma subunits in bovine brain G protein preparations was investigated using matrix-assisted laser desorption ionization (MALDI) mass spectrometry. Analysis of these G protein mixtures revealed at least four gamma subunit masses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::94992e46f9c576ccb5b3364e3c71b005
https://pubmed.ncbi.nlm.nih.gov/8175659
https://pubmed.ncbi.nlm.nih.gov/8175659
Publikováno v:
The Journal of biological chemistry. 268(31)
Activation of cGMP phosphodiesterase (PDE) by the rod G-protein transducin is a key event in visual signal transduction in vertebrate photoreceptor cells. Interaction between the GTP-bound form of the alpha-subunit of transducin (alpha t*) and the PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::389fb5055023db1334cfaa3d7108629e
https://pubmed.ncbi.nlm.nih.gov/8226888
https://pubmed.ncbi.nlm.nih.gov/8226888