Zobrazeno 1 - 10
of 14
pro vyhledávání: '"K. L. Rost"'
Publikováno v:
Pneumologie. 56:599-604
Background Controlled clinical trials have shown efficacy of high-dose ciprofloxacin for hospital-acquired (HAP) or nosocomial pneumonia. But it has yet to be demonstrated whether this good efficacy also holds true for routine intensive-care patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a715dfb89b395002b491b546da9e233
https://doi.org/10.1055/s-2002-34606
https://doi.org/10.1055/s-2002-34606
Publikováno v:
Hepatology. 23:1491-1497
Nonlinear kinetics of omeprazole and its metabolites were investigated after treatment with repeated high doses. Extensive metabolizers relating to cytochrome P450 2C19 (CYP2C19) activity received for 1 week either omeprazole at 40 mg/d (n = 14) or 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a304e70d0508489c376cdfde6183de
https://doi.org/10.1002/hep.510230628
https://doi.org/10.1002/hep.510230628
Interaction study of lomefloxacin and ciprofloxacin with omeprazole and comparative pharmacokinetics
Publikováno v:
Antimicrobial Agents and Chemotherapy. 39:1045-1049
To assess whether or not concomitant omeprazole treatment influences the pharmacokinetics of lomefloxacin and ciprofloxacin, a randomized, double-blind four-way-crossover study was performed. Another objective was to compare the pharmacokinetics of l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf15642d3cdb7cbd02740fe3b5e3346
https://doi.org/10.1128/aac.39.5.1045
https://doi.org/10.1128/aac.39.5.1045
Autor:
K L, Rost
Publikováno v:
Zeitgeschichte. 28(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::803dbaa549ff88bf645cabc7f283ed29
https://pubmed.ncbi.nlm.nih.gov/18165989
https://pubmed.ncbi.nlm.nih.gov/18165989
Publikováno v:
Pneumologie (Stuttgart, Germany). 56(10)
Controlled clinical trials have shown efficacy of high-dose ciprofloxacin for hospital-acquired (HAP) or nosocomial pneumonia. But it has yet to be demonstrated whether this good efficacy also holds true for routine intensive-care patients outside of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f2f53a572433ce4edd72da9852d82f06
https://pubmed.ncbi.nlm.nih.gov/12375221
https://pubmed.ncbi.nlm.nih.gov/12375221
Publikováno v:
International journal of clinical pharmacology and therapeutics. 37(11)
Omeprazole is an inducer of human cytochrome P450 1A (CYP1A) enzymes, but shows inhibitory effects on CYP2C19 and CYP3A4. In this study, a potential inhibitory effect of omeprazole on caffeine metabolism, a validated CYP1A2 marker, was examined.A ran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::79f99e2cf1575a11fefc44932d56c883
https://pubmed.ncbi.nlm.nih.gov/10584979
https://pubmed.ncbi.nlm.nih.gov/10584979
Publikováno v:
International journal of clinical pharmacology and therapeutics. 37(1)
Thymosin alpha1, an immunomodulatory endogenous peptide, has been shown to be effective in the treatment of chronic hepatitis B and C. In this study, single- and 5-day multiple-dose pharmacokinetics were characterized in nine Caucasian volunteers aft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::96328f4a4d55130055f2dd7de7af82b0
https://pubmed.ncbi.nlm.nih.gov/10027483
https://pubmed.ncbi.nlm.nih.gov/10027483
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 115:405-406
Reducing the workload of the beta cell by inhibiting insulin secretion may provide beneficial effects for patients with type 2 diabetes. The aim of this study was to investigate the effect of NN414, a beta cell selective potassium channel opener in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04414fdd609d85cbbc38d9899807f528
https://doi.org/10.1055/s-2007-973062
https://doi.org/10.1055/s-2007-973062
Publikováno v:
International journal of clinical pharmacology and therapeutics. 35(1)
Lansoprazole has been shown to induce cytochrome P450 1A (CYP1A) and CYP3A enzymes in human hepatocytes in vitro. In this study, urinary excretion of 6 beta-hydroxycortisol (6 beta-OHF) and D-glucaric acid (D-GA) were used to investigate the potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c4bc1846cbd01367163399afc88f479c
https://pubmed.ncbi.nlm.nih.gov/9021436
https://pubmed.ncbi.nlm.nih.gov/9021436
Publikováno v:
European journal of clinical pharmacology. 44
A population kinetic analysis was carried out on sparse plasma gentamicin (GE) concentration data from 469 neonates obtained as part of a routine therapeutic drug monitoring (TDM) programme in the hospital neonatology unit. The best predictors of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2502194807b9dee606930a7da933bf8d
https://pubmed.ncbi.nlm.nih.gov/8486141
https://pubmed.ncbi.nlm.nih.gov/8486141