Emergence of a multidrug-resistant and virulent Streptococcus pneumoniae lineage mediates serotype replacement after PCV13: an international whole-genome sequencing study

Autor: Stephanie W Lo, Kate Mellor, Robert Cohen, Alba Redin Alonso, Sophie Belman, Narender Kumar, Paulina A Hawkins, Rebecca A Gladstone, Anne von Gottberg, Balaji Veeraraghavan, K L Ravikumar, Rama Kandasamy, Sir Andrew J Pollard, Samir K Saha, Godfrey Bigogo, Martin Antonio, Brenda Kwambana-Adams, Shaper Mirza, Sadia Shakoor, Imran Nisar, Jennifer E Cornick, Deborah Lehmann, Rebecca L Ford, Betuel Sigauque, Paul Turner, Jennifer Moïsi, Stephen K Obaro, Ron Dagan, Idrissa Diawara, Anna Skoczyńska, Hui Wang, Philip E Carter, Keith P Klugman, Gail Rodgers, Robert F Breiman, Lesley McGee, Stephen D Bentley, Carmen Muñoz-Almagro, Emmanuelle Varon, Abdullah Brooks, Alejandra Corso, Alexander Davydov, Alison Maguire, Anmol Kiran, Benild Moiane, Bernard Beall, Chunjiang Zhao, David Aanensen, Dean Everett, Diego Faccone, Ebenezer Foster-Nyarko, Ebrima Bojang, Ekaterina Egorova, Elena Voropaeva, Eric Sampane-Donkor, Ewa Sadowy, Geetha Nagaraj, Helio Mucavele, Houria Belabbès, Naima Elmdaghri, Jennifer Verani, Jeremy Keenan, John Lees, Jyothish N Nair Thulasee Bhai, Kedibone Ndlangisa, Khalid Zerouali, Leon Bentley, Leonid Titov, Linda De Gouveia, Maaike Alaerts, Margaret Ip, Maria Cristina de Cunto Brandileone, Md Hasanuzzaman, Metka Paragi, Michele Nurse-Lucas, Mignon du Plessis, Mushal Ali, Nicholas Croucher, Nicole Wolter, Noga Givon-Lavi, Nurit Porat, Özgen Köseoglu Eser, Pak-Leung Ho, Patrick Eberechi Akpaka, Paula Gagetti, Peggy-Estelle Tientcheu, Pierra Law, Rachel Benisty, Rafal Mostowy, Roly Malaker, Samanta Cristine Grassi Almeida, Sanjay Doiphode, Shabir Madhi, Shamala Devi Sekaran, Stuart Clarke, Somporn Srifuengfung, Susan Nzenze, Tamara Kastrin, Theresa Ochoa, Waleria Hryniewicz, Yulia Urban

Publikováno v: The Lancet Microbe. 3:e735-e743

Background Serotype 24F is one of the emerging pneumococcal serotypes after the introduction of pneumococcal conjugate vaccine (PCV). We aimed to identify lineages driving the increase of serotype 24F in France and place these findings into a global

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e81bdf0d79c33a23902726bdb023c2a
https://doi.org/10.1016/s2666-5247(22)00158-6

Overcoming Data Bottlenecks in Genomic Pathogen Surveillance

Autor: Pilar Donado-Godoy, Elmer M Herrera, Monica Abrudan, John Stelling, Khalil Abudahab, Jolaade J Ajiboye, Marietta L Lagrada, D Sravani, Iruka N. Okeke, Celia C. Carlos, Alejandra Arevalo, Varun Shamanna, Melissa L Masim, Polle Krystle V Macaranas, Carolin Vegvari, Nicole E. Wheeler, Erkison Ewomazino Odih, Anderson O Oaikhena, Sonia Sia, Geetha Nagaraj, Mihir Kekre, Erik C D Osma Castro, Agnettah M Olorosa, Ayorinde O Afolayan, Sophia David, Harry Harste, June M Gayeta, Vandana Govindan, Silvia Argimón, Steffimole Rose, Kundur N Ravishankar, Anthony Underwood, K L Ravikumar, Ali Molloy, Johan Fabian Bernal, Maria Fernanda Valencia, Akshata Prabhu, David M. Aanensen, M R Shincy, Ben Taylor, Dawn Muddyman

Publikováno v: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America

Performing whole genome sequencing (WGS) for the surveillance of antimicrobial resistance offers the ability to determine not only the antimicrobials to which rates of resistance are increasing, but also the evolutionary mechanisms and transmission r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f505fdc58aae864d3354eb348f8c678
https://doi.org/10.1093/cid/ciab785

Good Financial Grant Practice: A Tool for Developing and Demonstrating Institutional Financial and Grant Management Capacity in Global Health

Autor: Erik C D Osma Castro, D Sravani, Maria Fernanda Valencia, June M Gayeta, Akshata Prabhu, Jolaade J Ajiboye, Vandana Govindan, Ben Taylor, Marietta L Lagrada, K L Ravikumar, Iruka N. Okeke, Erkison Ewomazino Odih, Genevieve Kiff, Varun Shamanna, Dawn Muddyman, Alejandra Arevalo, Mihir Kekre, Nicole E. Wheeler, Monica Abrudan, Pilar Donado-Godoy, David Sophia, Steffimole Rose, Polle Krystle V Macaranas, Celia C. Carlos, Harry Harste, Ayorinde O Afolayan, M R Shincy, David M. Aanensen, Anthony Underwood, Anderson O Oaikhena, Elmer M Herrera, Johan Fabian Bernal, Silvia Argimón, Khalil Abudahab, K N Ravishankar, Geetha Nagaraj, Agnettah M Olorosa, Akindele Olupelumi Adebiyi

Publikováno v: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America

The administration and governance of grant funding across global health organizations presents enormous challenges. Meeting these challenges is crucial to ensuring that funds are used in the most effective way to improve health outcomes, in line with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1380e1e51236d4ae406d6fdfec4aaa0b
http://europepmc.org/articles/PMC8634540

Implementing Whole-Genome Sequencing for Ongoing Surveillance of Antimicrobial Resistance: Exemplifying Insights IntoKlebsiella pneumoniae

Autor: Anderson O Oaikhena, Sophia David, Monica Abrudan, Carolin Vegvari, Mihir Kekre, Celia C. Carlos, Alejandra Arevalo, Erik C D Osma Castro, Ayorinde O Afolayan, Geetha Nagaraj, Vandana Govindan, Agnettah M Olorosa, M R Shincy, Anthony Underwood, K L Ravikumar, Ali Molloy, June M Gayeta, David M. Aanensen, Silvia Argimón, Ben Taylor, Harry Harste, D Sravani, Iruka N. Okeke, Erkison Ewomazino Odih, Varun Shamanna, Polle Krystle V Macaranas, Marietta L Lagrada, Jolaade J Ajiboye, Steffimole Rose, Dawn Muddyman, Nicole E. Wheeler, Johan Fabian Bernal, K N Ravishankar, Elmer M Herrera, Maria Fernanda Valencia, Akshata Prabhu, Khalil Abudahab, Pilar Donado-Godoy

Publikováno v: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America

In this Supplement, we detail outputs of the National Institute for Health Research Global Health Research Unit on Genomic Surveillance of Antimicrobial Resistance project, covering practical implementation of whole-genome sequencing across our conso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a03aa61a42c89a9864495529cefc1b
https://doi.org/10.1093/cid/ciab795

Whole-Genome Sequencing Of Omicron Identified Multiple Outbreaks And Introduction Events In India During November 2021 and January 2022

Autor: Shreedhanya D Marathe, Varun Shamanna, Geetha Nagaraj, S Nischita, Muthumeenakshi Bhaskaran, K L Ravikumar

The variant of Concern(VOC), Omicron is the predominant variant circulating throughout the world of the SARS COV2 pandemic during the third wave including India. The World Health Organisation has designated this highly mutated variant as a VOC due to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4748de439430a2f5d83291f6c0057e46
https://doi.org/10.1101/2022.04.20.22270880