Zobrazeno 1 - 10
of 74
pro vyhledávání: '"K. L. Paul Sung"'
Autor:
K. L. Paul Sung, Wei Huang, Peter C. Chen, Chunli Wang, Chunming Xu, Qingjia Chi, Cheng Chen, Peixing Chen, Yongqiang Sha, Kang Xu, Li Yang
Publikováno v:
Biotechnology Letters. 42:1567-1579
Interleukin (IL)-1β in the joint cavity increases to promote healing after anterior cruciate ligament (ACL) injury. Synovial tissue is a major joint microenvironmental regulator after ACL injury. The purpose of this study was to investigate the effe
Autor:
Liwei Zheng, Cheng Chen, Wenbin Yang, K. L. Paul Sung, Jing Xie, Xuedong Zhou, Chunli Wang, Jue Wang
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 12:e550-e565
The healing mechanism of cruciate ligaments is not well elucidated. Crosstalk between adjacent tissues in the knee joint plays an important role in wound healing and tissue regeneration, but the gelatinase modulation in posterior cruciate ligament fi
Publikováno v:
Journal of tissue engineering and regenerative medicineREFERENCES. 14(8)
Anterior cruciate ligament (ACL) regeneration is severely affected by the injury-induced overexpression of matrix metalloproteinases (MMPs) and downregulation of lysyl oxidase (LOX). Previous studies have focused on how the expression of MMPs and dow
Publikováno v:
Gene. 766:145149
Background Crosstalk between posterior cruciate ligament fibroblasts (PCLfs) and synoviocytes (SCs) significantly modifies the homeostatic balance of the extracellular matrix (ECM) and appears to post a prominent affection for wound healing of PCL. I
Mechano growth factor-C24E, a potential promoting biochemical factor for ligament tissue engineering
Autor:
Yang Song, Chunli Wang, Yonggang Lv, Kang Xu, Xingshuang Ma, K. L. Paul Sung, Can Yu, Li Yang, Juila Li Zhong
Publikováno v:
Biochemical Engineering Journal. 105:249-263
Ligaments play an important role in stabilizing and balancing knee joint movement. Anterior cruciate ligament (ACL) injuries remain a challenge in clinical and experimental settings due to the poor healing potential of ACL injuries. This study invest
Publikováno v:
Connective tissue research. 60(4)
Purposes: To investigate the ability of synoviocytes (SCs) in regulating MMPs expression in the posterior cruciate ligament fibroblasts (PCLfs) after TNF-α treatment, to test whether a specific inflammation inhibitor Bay11-7082 can antagonize the ex
Publikováno v:
Connective tissue research. 59(4)
Purposes The anterior cruciate ligament (ACL) has poor functional healing response. The synovial tissue surrounding ACL ligament might be a major regulator of the microenvironment in the joint cavity after ACL injury, thus affecting the repair proces
Autor:
Kang Xu, Nianguo Dong, Li Yang, Yongqiang Sha, Mohanad Kh Al-ani, K. L. Paul Sung, Chunli Wang, Xuefeng Qiu, Yanjun Sun
Publikováno v:
Journal of biomechanics. 66
Current study investigated bone morphogenetic protein 12 (BMP12) and connective tissue growth factor (CTGF) activate tendon derived stem cells (TDSCs) tenogenic differentiation, and promotion of injured tendon regeneration. TDSCs were transfected wit
Autor:
Li Yang, Peter C. Chen, Chunming Xu, Wei Huang, Jing Xie, Jiahuan Jiang, Yanjun Zhang, K. L. Paul Sung, Yan Xu
Publikováno v:
Injury. 44:893-900
Lysyl oxidase (LOX) family has the capacity to catalyse the cross-linking of collagen and elastin, implicating its important fundamental roles in tissue development and injury healing. However, the variations in expression of the LOX family in the no
Autor:
Peter C. Chen, Kevin Zhou, Jing Xie, Chunli Wang, Wei Huang, Lin Yin, Yanjun Zhang, Li Yang, K. L. Paul Sung, Chunmin Xu, Jiahuang Jiang
Publikováno v:
Knee Surgery, Sports Traumatology, Arthroscopy. 22:1997-2006
It was reported that not only ACL but also the synovium may be the major regulator of matrix metalloproteinases (MMPs) in synovial fluids after ACL injury. In order to further confirm whether synovium is capable of regulating the microenvironment in