Zobrazeno 1 - 10
of 105
pro vyhledávání: '"K. L. Leenders"'
Autor:
S. S. Lövdal, G. Carli, B. Orso, M. Biehl, D. Arnaldi, P. Mattioli, A. Janzen, E. Sittig, S. Morbelli, J. Booij, W. H. Oertel, K. L. Leenders, S. K. Meles
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Parkinson’s disease (PD) is characterized by a progressive loss of dopaminergic neurons in the substantia nigra. Recent literature has proposed two subgroups of PD. The “body-first subtype” is associated with a prodrome of isolated REM
Externí odkaz:
https://doaj.org/article/623397c61006441a96cce3b38494ef22
Publikováno v:
Neural Plasticity, Vol 10, Iss 1-2, Pp 121-128 (2003)
In the last decade, expanding animal studies on the cerebral organization of reward processing toward human in vivo situations has become possible. In this review, we define some of the concepts associated with reward, summarize the crucial importanc
Externí odkaz:
https://doaj.org/article/4fcb3947c1354418afaefcbdd7222934
Autor:
K. L. Leenders, W. H. Oertel
Publikováno v:
Neural Plasticity, Vol 8, Iss 1-2, Pp 99-110 (2001)
Parkinson's disease is one of the most frequent neurodegenerative brain diseases. Its time course is slow and is characterized by progressive loss of dopaminergic and other brainstem neurons resulting in malfunctioning of the cerebral neuronal system
Externí odkaz:
https://doaj.org/article/a9e2de301fda47d1b1909efbdb37d0fe
Publikováno v:
NeuroPsychopharmacotherapy ISBN: 9783319560151
NeuroPsychopharmacotherapy
NeuroPsychopharmacotherapy ISBN: 9783030620585
NeuroPsychopharmacotherapy
NeuroPsychopharmacotherapy ISBN: 9783030620585
Medical therapy in de novo Parkinson’s disease typically starts with a dopamine agonist or levodopa in combination with a decarboxylase inhibitor or if symptoms are still very mild with a MAO-B inhibitor. When patients do not (or no longer) respond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5048ec572adbbe51e1bc7e831ef61a6a
https://doi.org/10.1007/978-3-319-56015-1_288-1
https://doi.org/10.1007/978-3-319-56015-1_288-1
Publikováno v:
Neural Plasticity, Vol 10, Iss 1-2, Pp 121-128 (2003)
Neural Plasticity
Neural Plasticity
In the last decade, expanding animal studies on the cerebral organization of reward processing toward human in vivo situations has become possible. In this review, we define some of the concepts associated with reward, summarize the crucial importanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64ecec27a890fdadb310bd3ed563a227
https://doaj.org/article/4fcb3947c1354418afaefcbdd7222934
https://doaj.org/article/4fcb3947c1354418afaefcbdd7222934
Publikováno v:
Clinical Pharmacology & Therapeutics. 70:33-41
Objective: Parameters of a pharmacokinetic-pharmacodynamic (PK-PD) model of levodopa have been claimed to reflect the magnitude of the dopaminergic deficit in patients with Parkinson's disease. The aim of this study was to correlate such parameters w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ae87644bc583397fe199b795a48bd7
https://doi.org/10.1067/mcp.2001.116328
https://doi.org/10.1067/mcp.2001.116328
Autor:
U Roelcke, K. L. Leenders
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 127:2-8
This article reviews possible clinical applications of positron emission tomography (PET) in brain tumor patients. PET allows quantitative assessment of brain tumor pathophysiology and biochemistry. It therefore provides different information about t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6234fb8cb4b9d02f84b979186170b727
https://doi.org/10.1007/s004320000158
https://doi.org/10.1007/s004320000158
Publikováno v:
Hum Brain Mapp
The computerized brain atlas (CBA) and statistical parametric mapping (SPM) are two procedures for voxel‐based statistical evaluation of PET activation studies. Each includes spatial standardization of image volumes, computation of a statistic, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0a926e5c3132acf3bf680df53a9444
https://doi.org/10.1002/(sici)1097-0193(1999)8:4<245::aid-hbm8>3.0.co
https://doi.org/10.1002/(sici)1097-0193(1999)8:4<245::aid-hbm8>3.0.co
Autor:
K. L. Leenders, U. Roelcke
Publikováno v:
Der Onkologe. 4:595-598
Im folgenden wird die Wertigkeit von PET anhand von Fragen, wie sie immer wieder im neuroonkologischen Alltag auftreten, diskutiert.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::addd39a42f4af54a6533aec8891c1488
https://doi.org/10.1007/s007610050242
https://doi.org/10.1007/s007610050242