Zobrazeno 1 - 6
of 6
pro vyhledávání: '"K. L. L. Fong"'
Autor:
P Fishman, A R van Troostenburg, W D H Carey, W D Kerns, I Cohn, E V Clark, K L L Fong, S. Bar-Yehuda, Steven J. Warrington, M H Silverman
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 42:534-542
Objectives: To assess safety, tolerability, pharmacokinetics and hemodynamic effects of oral CF 101, an A3 adenosine receptor (A3AR) agonist, in healthy men. Methods: One single and 1 repeated dose, parallel-group, ascending dose, double-blind and pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a78e6556be75c9c2c5cf4a6989c561b6
https://doi.org/10.5414/cpp42534
https://doi.org/10.5414/cpp42534
Autor:
K L L Fong, K.E. Boyle, R. J. Shebuski, D. Williams, P. McDevitt, M.E. Reff, T.S. Sellers, M.D. Rosa, J.J. Trill, K. Johanson
Publikováno v:
Fibrinolysis. 4:131-140
Summary We have constructed, expressed and purified a novel thrombolytic, finger protease (FP), composed of only the finger and serine protease domains of t-PA. This molecule, when compared to t-PA, has improved pharmacokinetics (slower plasma cleara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dad1b28d2e5178e09b8138b21c4370e9
https://doi.org/10.1016/s0268-9499(05)80044-x
https://doi.org/10.1016/s0268-9499(05)80044-x
Publikováno v:
XIth International Congress on Thrombosis and Haemostasis.
The pharmacokinetics of SK&F recombinant two-cha1n tissue-type plasminogen activator (tPA) following Intravenous (i.v.) infusion were characterized in anesthetized, open chested mongrel dogs in which artificial Intracoronary thrombi were formed. SK&F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6ef54134dcb0f782780938cc67af0f9
https://doi.org/10.1055/s-0038-1644399
https://doi.org/10.1055/s-0038-1644399
Publikováno v:
XIth International Congress on Thrombosis and Haemostasis.
Hepatic uptake has been proposed as the major mechanism of tPA clearance from systemic circulation. However, our recent studies demonstrated that tPA was rapidly Inactivated through complexation with protease Inhibitors in dog plasma In vitro, and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9415fced8d4ce422b3db00f067644588
https://doi.org/10.1055/s-0038-1644398
https://doi.org/10.1055/s-0038-1644398
Autor:
Robert Vince, K. L. L. Fong
Publikováno v:
Chemischer Informationsdienst. 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b3fb475ab8f89420b973200324af99d
https://doi.org/10.1002/chin.197851358
https://doi.org/10.1002/chin.197851358
Autor:
L.M. Cotter, R. J. Shebuski, C. S. Crysler, T.K. Chen, K.E. Boyle, A. Fujita, K L L Fong, D.S. Pfarr, M.E. Reff, D. Williams, J. Noveral, B. A. Mico, R.W. Connors, B.A. Berkowitz, J.J. Trill
Publikováno v:
Fibrinolysis. 2:29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e18b286bddba5f90b66628f6e467c90e
https://doi.org/10.1016/0268-9499(88)90407-9
https://doi.org/10.1016/0268-9499(88)90407-9