Zobrazeno 1 - 10
of 14
pro vyhledávání: '"K. K. Dharmappa"'
Autor:
Aladahalli S. Giresha, Deepadarshan Urs, J. G. Manjunatha, P. Sophiya, B. H. Supreetha, Shankar Jayarama, K. K. Dharmappa
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Human group IIA secreted phospholipase A2 (GIIA) is a key enzyme in inflammatory reactions, worsening the condition of several chronic inflammatory diseases. The natural inhibitors of GIIA potentially block the production of inflammatory med
Externí odkaz:
https://doaj.org/article/5d05f6091aa74a9688d7eac277ba4737
Autor:
P. Sophiya, Deepadarshan Urs, Jafar K. Lone, A. S. Giresha, H. Krishna Ram, J. G. Manjunatha, Hamed A. El-Serehy, M. Narayanappa, J. Shankar, Ragini Bhardwaj, Sameer Ahmad Guru, K. K. Dharmappa
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Human phospholipase A2 group IIa (sPLA2IIa) is an inflammatory enzyme that plays a significant role in tumorigenesis. Inhibiting the sPLA2IIa enzyme with an effective molecule can reduce the inflammatory response and halt cancer progression. The pres
Externí odkaz:
https://doaj.org/article/e4d1a330171f41248fb2f6520f06e818
Publikováno v:
Pharmacognosy Research
Background: Inflammation is a normal and necessary prerequisite to healing of the injured tissues. Inflammation contributes to all disease process including immunity, vascular pathology, trauma, sepsis, chemical, and metabolic injuries. The secretory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::234e413f9c9bfd57492865a13dbc525e
https://pubmed.ncbi.nlm.nih.gov/28539742
https://pubmed.ncbi.nlm.nih.gov/28539742
Autor:
K. K. Dharmappa, Raju Venkatesh Kumar, B.K. Sharath, M. Yariswamy, Vikram Joshi, Shivaprasad H. Venkatesha, Bannikuppe S. Vishwanath
Publikováno v:
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 164:111-116
In the present study we describe the purification and characterization of Malabarase, a serine protease from Trimeresurus malabaricus venom. Purification was achieved by gel-permeation chromatography on Sephadex G-75 followed by ion-exchange chromato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c01945e8f98eda080160f0c9ad9f7f7
https://doi.org/10.1016/j.cbpb.2012.11.004
https://doi.org/10.1016/j.cbpb.2012.11.004
Autor:
M. A. Shekhar, S. A. Kannum, K. K. Dharmappa, Cletus Jmd’ Souza, H. S. Ashrafulla, Noor Mohamed Jameel, Bannikuppe S. Vishwanath, Riyaz Mohamed, Shaista Tarannum, Lokanath Rai
Publikováno v:
Molecular and Cellular Biochemistry. 345:69-76
The halo 6-fatty acid esters of L-ascorbic acid 3a, 3b and 6-fatty acid esters of L-ascorbic acid 5a-g were achieved from L-ascorbic acid 1. Compounds 3a, 3b and 5a-g were evaluated for anti-oxidant, anti-lipid peroxidation, and secretory phospholipa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1284bac72083a0f2193df068c9533ab
https://doi.org/10.1007/s11010-010-0561-z
https://doi.org/10.1007/s11010-010-0561-z
Publikováno v:
Inflammopharmacology. 18:25-31
Some of the legumes, spices and medicinal herbs rich in genistein are known for their anti-inflammatory properties. Anti-inflammatory property of these herbs is determined by subjecting secretory phospholipase A(2) (sPLA(2)) inhibition, a key enzyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d34bcb15c7f04b788d15d7ffbb46aec
https://doi.org/10.1007/s10787-009-0018-8
https://doi.org/10.1007/s10787-009-0018-8
Autor:
B. L. Nanda, R. Rajesh, Holenarasipura V. Shivaprasad, K. K. Dharmappa, Bannikuppe S. Vishwanath
Publikováno v:
Journal of Ethnopharmacology. 123:106-109
Aim of the study To validate the scientific basis of plant latex to stop bleeding on fresh cuts. Cysteine protease(s) from Asclepias curassavica (Asclepiadaceae) plant latex was assessed for pro-coagulant and thrombin like activities. Materials and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa03c71300f103709176f26757072518
https://doi.org/10.1016/j.jep.2009.02.016
https://doi.org/10.1016/j.jep.2009.02.016
Autor:
Holenarasipura V. Shivaprasad, Riyaz Mohamed, K. K. Dharmappa, Bannikuppe S. Vishwanath, Raju Venkatesh Kumar, A. Nataraju
Publikováno v:
Planta Medica. 75:211-215
Oleanolic acid, a triterpenoid known for its anti-inflammatory properties, is commonly present in several medicinal plants. The present study evaluated the effect of oleanolic acid on sPLA (2), a key enzyme in inflammatory reactions. Oleanolic acid i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b49bbe7539905de64b26311e1d55850b
https://doi.org/10.1055/s-0028-1088374
https://doi.org/10.1055/s-0028-1088374
Autor:
K. K. Dharmappa, M. Riyaz, R. Venkatesh Kumar, Jalahalli M. Siddesha, Bannikuppe S. Vishwanath, Shaista Tarannum, Holenarasipura V. Shivaprasad, R. Rajesh
Publikováno v:
Journal of Thrombosis and Thrombolysis. 28:304-308
In the present study we evaluated the presence of cysteine protease from the latex of four plants Asclepias curassavica L., Calotropis gigantea R.Br., Pergularia extensa R.Br. and Cynanchum puciflorum R.Br. belongs to the family Asclepiadaceae. Cyste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee30b27573b7a7cb080b3182f303f1d6
https://doi.org/10.1007/s11239-008-0290-2
https://doi.org/10.1007/s11239-008-0290-2