Zobrazeno 1 - 10
of 29
pro vyhledávání: '"K. K. Changani"'
Publikováno v:
Modern Magnetic Resonance ISBN: 9783319282756
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdceeb96d157e0ab2efb0ebfa368a99d
https://doi.org/10.1007/978-3-319-28275-6_101-1
https://doi.org/10.1007/978-3-319-28275-6_101-1
Drug discovery and development is a resource intensive and risky process. Compound failure rates remain high and principally occur in the most expensive clinical stages of pharmaceutical research. There is therefore considerable interest in the appli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19fbabec02d93ef1c52cc623665a8f8d
https://doi.org/10.1039/9781849732918-00465
https://doi.org/10.1039/9781849732918-00465
Autor:
P D, Hockings, K K, Changani, N, Saeed, D G, Reid, J, Birmingham, P, O'Brien, J, Osborne, C N, Toseland, R E, Buckingham
Publikováno v:
Diabetes, obesitymetabolism. 5(4)
This study aimed to chart the time course and durability of the effects of rosiglitazone, a potent thiazolidinedione-based peroxisome proliferator-activated receptor gamma agonist, on hepatic steatosis and intramyocellular lipid in an animal model of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5eefa7d854d272584db9d9dcc5581ddd
https://pubmed.ncbi.nlm.nih.gov/12795656
https://pubmed.ncbi.nlm.nih.gov/12795656
Publikováno v:
Diabetes, obesitymetabolism. 5(2)
To characterize evolution and distribution of abdominal adipose fat between 6 and 18 weeks of age in an animal model of energy consumption based on mice overexpressing the mitochondrial uncoupler protein 3 (UCP-3).T2-weighted multislice MRI was perfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c989bcee4deb5fc0ab18de9c8818b6ba
https://pubmed.ncbi.nlm.nih.gov/12630934
https://pubmed.ncbi.nlm.nih.gov/12630934
Publikováno v:
Transplantation. 68(3)
Organ cold storage times may be extended by modifications to organ preservation solutions.Three preservation solutions were investigated for their ability to maintain viable hepatic bioenergetics in stored pig livers: modified University of Wisconsin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4b9c97bdaa77ff9c2221b03b2af3f7e7
https://pubmed.ncbi.nlm.nih.gov/10459537
https://pubmed.ncbi.nlm.nih.gov/10459537
Autor:
K K, Changani, M, Ala-Korpela, B J, Fuller, S, Mierisova, D J, Bryant, S D, Taylor-Robinson, B R, Davidson, J D, Bell
Publikováno v:
NMR in biomedicine. 12(4)
A semi-automated, metabolite prior-knowledge-based, lineshape fitting analysis has been developed to assess the dynamic biochemical changes found in ex vivo 31P NMR pig liver preservation studies. Due to the inherent experimental limitations of the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1d2af33c6f431436f492d095441c59fe
https://pubmed.ncbi.nlm.nih.gov/10421911
https://pubmed.ncbi.nlm.nih.gov/10421911
Publikováno v:
Biochimica et biophysica acta. 1380(2)
In vivo -NMR was employed to determine the hepatic fate of infused [1-]-d-glucose (200 mg/kg) following ad libitum or routine meal feeding (RMF) regimes imposed during pregnancy. Hepatic glycogen synthesis was measured immediately following the last
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7ace33d0536542e1cfbce601c0182a10
https://pubmed.ncbi.nlm.nih.gov/9565686
https://pubmed.ncbi.nlm.nih.gov/9565686
Autor:
K K, Changani, B J, Fuller, D J, Bryant, J D, Bell, M, Ala-Korpela, S D, Taylor-Robinson, D P, Moore, B R, Davidson
Publikováno v:
Journal of hepatology. 26(2)
We have developed a quick, non-invasive method for measuring the ability of an isolated preserved liver to regenerate high energy phosphate nucleotides without the need for biopsy. Using 31P MRS we have monitored the hepatic energetics of intact cold
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::97a4b8371bc0d6f8ea09d4e34a4c7bde
https://pubmed.ncbi.nlm.nih.gov/9059955
https://pubmed.ncbi.nlm.nih.gov/9059955
Autor:
K K, Changani, B J, Fuller, J D, Bell, D J, Bryant, D P, Moore, S D, Taylor-Robinson, B R, Davidson
Publikováno v:
Transplantation. 62(6)
The aim of this study was to assess the possibility of regenerating nucleotide triphosphates (NTP) in the pig liver following its harvest and subsequent storage on ice. This study has used a pig model that allowed human donor liver retrieval techniqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b3fcbabfbe92289a9f7c1012d9de125
https://pubmed.ncbi.nlm.nih.gov/8824479
https://pubmed.ncbi.nlm.nih.gov/8824479
Autor:
Doolette, Ashlea L.1, Smernik, Ronald J.1
Publikováno v:
Magnetic Resonance in Chemistry. Sep2015, Vol. 53 Issue 9, p679-685. 7p.