Výsledky vyhledávání - "K. Jeyaseelan"

Comparison of quantitative and qualitative scoring approaches for radiation-induced pulmonary fibrosis as applied to a preliminary investigation into the efficacy of mesenchymal stem cell delivery methods in a rat model

Autor: Li Ming Wang, Monica Serban, N. Ybarra, K. Jeyaseelan, Sangkyu Lee, Sungmi Jung, Avishek Chatterjee, Issam El Naqa, J. Seuntjens

Publikováno v: BJR Open

Objectives: Compare a quantitative, algorithm-driven, and qualitative, pathologist-driven, scoring of radiation-induced pulmonary fibrosis (RIPF). And using these scoring models to derive preliminary comparisons on the effects of different mesenchyma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb70a7c55c786473532847cc9cdd779
http://europepmc.org/articles/PMC8320116

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Mesenchymal Stem Cells Adopt Lung Cell Phenotype in Normal and Radiation-induced Lung Injury Conditions

Autor: Shirley Lehnert, Ahmed M. Maria, Monica Serban, Issam El Naqa, Sangkyu Lee, N. Ybarra, Ola M. Maria, Sergio Faria, Mostafa Y. Shalaby, K. Jeyaseelan, Jessica R. Perez, Jan Seuntjens

Publikováno v: Applied Immunohistochemistry & Molecular Morphology. 24:283-295

Lung tissue exposure to ionizing irradiation can invariably occur during the treatment of a variety of cancers leading to increased risk of radiation-induced lung disease (RILD). Mesenchymal stem cells (MSCs) possess the potential to differentiate in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c07aac8eb2ba50f32d6ebb77cc298a
https://doi.org/10.1097/pai.0000000000000180

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Bayesian network ensemble as a multivariate strategy to predict radiation pneumonitis risk

Autor: Jeffrey D. Bradley, Clifford G. Robinson, Issam El Naqa, Neil Kopek, Sangkyu Lee, Pascale Brisebois, K. Jeyaseelan, Sergio Faria, N. Ybarra, Jan Seuntjens

Publikováno v: Medical Physics. 42:2421-2430

Purpose: Prediction of radiation pneumonitis (RP) has been shown to be challenging due to the involvement of a variety of factors including dose–volume metrics and radiosensitivity biomarkers. Some of these factors are highly correlated and might a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::37c07284ca5f52b9f217ca76d8efb453
https://doi.org/10.1118/1.4915284

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A comparative analysis of longitudinal computed tomography and histopathology for evaluating the potential of mesenchymal stem cells in mitigating radiation-induced pulmonary fibrosis

Autor: Sangkyu Lee, K. Jeyaseelan, Ola M. Maria, Jessica R. Perez, N. Ybarra, Monica Serban, Li Ming Wang, Issam El Naqa, Jan Seuntjens

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports

Radiation-induced pulmonary fibrosis (RIPF) is a debilitating side effect that occurs in up to 30% of thoracic irradiations in breast and lung cancer patients. RIPF remains a major limiting factor to dose escalation and an obstacle to applying more p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4f87df1c92470a1d5bf8f7dd335b738
https://doi.org/10.1038/s41598-017-09021-7

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Evaluation and Visualization of Radiogenomic Modeling Frameworks for the Prediction of Normal Tissue Toxicities

Autor: Marie Duclos, Fabio Cury, Jessie Tao, N. Ybarra, Luis Souhami, Issam El Naqa, Asha K. Jeyaseelan, James Coates, Marc David, Sergio Faria

Publikováno v: IFMBE Proceedings ISBN: 9783319193861

We explore techniques for the evaluation and visualization of radiogenomic data-driven models in an effort to investigate the integration of genetic variations (single nucleotide polymorphisms [SNPs] and copy number variations [CNVs]) with dosimetric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::62e00c97c67c8eb5ddd7c0bc1389beb1
https://doi.org/10.1007/978-3-319-19387-8_127

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Investigation of Stem-like Cells Role in Regional Radiosensitivity of the Lung

Autor: Jan Seuntjens, Sangkyu Lee, Ola M. Maria, Jessica R. Perez, Shirley Lehnert, Lyne Kharbotly, K. Jeyaseelan, Ahmed M. Maria, Sergio Faria, Monica Serban, Issam El Naqa, N. Ybarra

Publikováno v: Journal of Stem Cell Research & Therapy.

Objective: Lung is a complex organ with puzzling patterns of radiosensitivity, depending on both the volume and the region of the lung irradiated. In this study, we aimed to investigate stem-like cells distribution in lung lobes and their potential r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d8aa0691e0653b2b45d80a43356f9228
https://doi.org/10.4172/2157-7633.1000298

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Contrasting analytical and data-driven frameworks for radiogenomic modeling of normal tissue toxicities in prostate cancer

Autor: Sergio Faria, Fabio Cury, Marc David, Asha K. Jeyaseelan, N. Ybarra, James Coates, Issam El Naqa, Luis Souhami, Marie Duclos

Publikováno v: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 115(1)

Background and purpose We explore analytical and data-driven approaches to investigate the integration of genetic variations (single nucleotide polymorphisms [SNPs] and copy number variations [CNVs]) with dosimetric and clinical variables in modeling

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c10c9361c6df062bebbf84d8b5c90d8
https://pubmed.ncbi.nlm.nih.gov/25818395

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