Zobrazeno 1 - 7
of 7
pro vyhledávání: '"K. Jeff Thrasher"'
Autor:
J. Scott Sawyer, Sandra L. Cockerham, K. Jeff Thrasher, Larry L. Froelich, Carlos R. Roman, Bach Nicholas J, Peter W. Stengel, Jerome H. Fleisch, Steven A. Silbaugh
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:249-252
A series of quinoline-substituted dihydroindoles has been synthesized and evaluated as antagonists of the cysLT 1 receptor. This series, exemplified by 2 (LY302905; pKi = 8.3 for inhibition of binding of 3 H-LTD 4 to guinea pig lung membranes), repre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::438717985a22985e2fc666797a7adefa
https://doi.org/10.1016/0960-894x(96)00013-3
https://doi.org/10.1016/0960-894x(96)00013-3
Autor:
Alan David Palkowitz, Donald B. Boyd, Kenneth Lee Hauser, Mitchell I. Steinberg, Karen M. Zimmerman, K. Jeff Thrasher
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:1015-1020
A novel series of benzimidazole angiotensin II (Ang II) receptor antagonists (4, 13, 5, 17) were synthesized and compared pharmacologically to the previously described imidazole analogues (1, 3a-b).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8d0a626b825c642d1f71a428dada9e8
https://doi.org/10.1016/0960-894x(95)00159-q
https://doi.org/10.1016/0960-894x(95)00159-q
Autor:
Donald B. Boyd, Pfeifer William, Kumiko Takeuchi, Celia Ann Whitesitt, Jon K. Reel, Vasu Vasudevan, Alan David Palkowitz, Richard Lee Simon, Sally A. Wiest, Kenneth Lee Hauser, Aaron D. Kossoy, Jack B. Deeter, Lifer Sherryl Lynn, K. Jeff Thrasher, Winston Stanley Marshall, Karen M. Zimmerman, Mitchell I. Steinberg
Publikováno v:
ACS Symposium Series ISBN: 9780841231603
Computer-Aided Molecular Design: Applications in Agrochemicals, Materials, and Pharmaceuticals
Computer-Aided Molecular Design: Applications in Agrochemicals, Materials, and Pharmaceuticals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d864bf657ccd6412e142eb39a941696c
https://doi.org/10.1021/bk-1995-0589.ch002
https://doi.org/10.1021/bk-1995-0589.ch002
Autor:
Erik James Hembre, Jian Eric Hong, Louis Nickolaus Jungheim, Kevin Matthew Gardinier, Kenneth Allen Savin, K. Jeff Thrasher
Publikováno v:
HETEROCYCLES. 67:543
Regioselective pyridine metallation chemistry was used to produce N-(3-chloropyridin-4-ylmethyl)-N-methyl-1-(3,5-bis-trifluoromethylbenzyl)-5-phenyl-1H-[1,2,3]triazole-4-carboxamide (9a) and [l-(3,5-bis-trifluoromethyl-benzyl)-5-morpholin-4-yl-1H-[1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cb9c33a5828fab038ca7fd3ce3b93ce
https://doi.org/10.3987/com-05-s(t)64
https://doi.org/10.3987/com-05-s(t)64
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Autor:
CHARLES H. REYNOLDS, M. KATHARINE HOLLOWAY, HAROLD K. COX, Bruce R. Gelin, Donald B. Boyd, Alan D. Palkowitz, K. Jeff Thrasher, Kenneth L. Hauser, Celia A. Whitesitt, Jon K. Reel, Richard L. Simon, William Pfeifer, Sherryl L. Lifer, Kumiko Takeuchi, Vasu Vasudevan, Aaron D. Kossoy, Jack B. Deeter, Mitchell I. Steinberg, Karen M. Zimmerman, Sally A. Wiest, Winston S. Marshall, Jenny M. Wai, Carol A. Venanzi, Ronald A. Buono, William J. Skawinski, Thomas J. Busanic, Thomas J. Venanzi, Randy J. Zauhar, Victor B. Luzhkov, Tudor I. Oprea, Chris M. W. Ho, Garland R. Marshall, Regine S. Bohacek, Colin McMartin, Nicholas Bodor, Ming-Ju Huang, R. M. Wolf, V. Fritsch, A. De Mesmaeker, J. Lebreton, A. Waldner, Terry R. Stouch, Howard E. Alper, Donna Bassolino, E. P. Jaeger, D. C. Pevear, P. J. Felock, G. R. Russo, A. M. Treasurywala, Stephen B. Bowlus, Steven H. Shaber, Mark A. Dekeyser, W. Ashley Harrison, Paul T. McDonald, G. W. Angle, Saad M. M. Ismail, Roger G. H. Downer, Richard J. Petroski, Roy Vaz, Krishna N. Reddy, Ujjana B. Nandihalli, Hee Jae Lee