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CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms

Publikováno v: Cancer Research. 79:3916-3927

Regulatory T cells (Treg) are immunosuppressive and negatively impact response to cancer immunotherapies. CREB-binding protein (CBP) and p300 are closely related acetyltransferases and transcriptional coactivators. Here, we evaluate the mechanisms by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dd60da0c82ed81285afa9302ce650a7
https://doi.org/10.1158/0008-5472.can-18-3622

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Apolipoprotein E Promotes Invasion in Oral Squamous Cell Carcinoma

Autor: Michael B. Prystowsky, Olivier Loudig, Berrin Ustun, Thomas J. Belbin, Jeffrey E. Segall, Ryung S. Kim, Thomas M. Harris, Thomas J. Ow, Sangeeta K. Jayakar, Margaret Brandwein-Gensler, Geoffrey Childs

Publikováno v: The American Journal of Pathology. 187:2259-2272

Oral squamous cell carcinoma (OSCC) patients generally have a poor prognosis, because of the invasive nature of these tumors. In comparing transcription profiles between OSCC tumors with a more invasive (worst pattern of tumor invasion 5) versus a le

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a59923710617683cf510826d408982e
https://doi.org/10.1016/j.ajpath.2017.06.016

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Mechanisms of Invasion in Head and Neck Cancer

Autor: Thomas J. Ow, Jeffrey E. Segall, Lizandra Jimenez, Sangeeta K. Jayakar

Publikováno v: Arch Pathol Lab Med

ContextThe highly invasive properties demonstrated by head and neck squamous cell carcinoma (HNSCC) are often associated with locoregional recurrence and lymph node metastasis in patients and is a key factor leading to an expected 5-year survival rat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e02dfc4ba8ed75d3869c1bc3048c338c
https://doi.org/10.5858/arpa.2014-0498-ra

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Conservation of Dcm-mediated cytosine DNA methylation in Escherichia coli

Autor: Robert D. Simon, Sarah Pounder, Stacy M. Hennick, Sangeeta K. Jayakar, Kevin T. Militello, Michelle L. Van Horne, Robert Maines, Mehr Qureshi

Publikováno v: FEMS Microbiology Letters. 328:78-85

In Escherichia coli, cytosine DNA methylation is catalyzed by the Dcm (DNA cytosine methyltransferase) protein and occurs at the second cytosine in the sequence 5′CCWGG3′. Although the presence of cytosine DNA methylation was reported over 35 yea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3eb65dcb49a03dff2b8b9f41ea76931
https://doi.org/10.1111/j.1574-6968.2011.02482.x

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Akademický článek

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Wafer-to-wafer bonding of nonplanarized MEMS surfaces using solder

Autor: G Woodward, Michael W. Putty, R Weston, S Zarabadi, Douglas Ray Sparks, K Jayakar, L Jordan, G Queen

Publikováno v: Journal of Micromechanics and Microengineering. 11:630-634

The fabrication and reliability of a solder wafer-to-wafer bonding process is discussed. Using a solder reflow process allows vacuum packaging to be accomplished with unplanarized complementary metal-oxide semiconductor (CMOS) surface topography. Thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fb8d9250e536a9be550d42c7644e0535
https://doi.org/10.1088/0960-1317/11/6/303

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Liquid chromatography–electrospray mass spectrometric identification of ginsenosides in Panax ginseng roots

Autor: K Jayakar, N Fuzzati, F Peterlongo, B. Gabetta, R Pace

Publikováno v: Journal of Chromatography A. 854:69-79

A high-performance liquid chromatographic method was developed for electrospray mass spectrometric analysis of ginsenosides in Panax ginseng roots. The analyses were performed on a reversed-phase C18 column using a binary eluent (aqueous 8 mM NH4OAc,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b87f3b3bd16ab9213a468ec4140141e3
https://doi.org/10.1016/s0021-9673(99)00463-x

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