Zobrazeno 1 - 10
of 35
pro vyhledávání: '"K. Janhunen"'
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 1008 (2024)
One aspect of reproducibility in preclinical research that is frequently overlooked is the physical condition in which physiological, pharmacological, or behavioural recordings are conducted. In this study, the physical conditions of mice were altere
Externí odkaz:
https://doaj.org/article/30cbaf1efa904314b2d2e7b0e7ee7522
Publikováno v:
Journal of Integrative Neuroscience, Vol 23, Iss 2, p 30 (2024)
Externí odkaz:
https://doaj.org/article/bf1721a1cdd74582ae18a8445fa71216
Autor:
María Arroyo-Araujo, Bernhard Voelkl, Clément Laloux, Janja Novak, Bastijn Koopmans, Ann-Marie Waldron, Isabel Seiffert, Helen Stirling, Katharina Aulehner, Sanna K Janhunen, Sylvie Ramboz, Heidrun Potschka, Johanna Holappa, Tania Fine, Maarten Loos, Bruno Boulanger, Hanno Würbel, Martien J Kas
Publikováno v:
PLoS Biology, Vol 20, Iss 11, p e3001886 (2022)
The influence of protocol standardization between laboratories on their replicability of preclinical results has not been addressed in a systematic way. While standardization is considered good research practice as a means to control for undesired ex
Externí odkaz:
https://doaj.org/article/42a716b06c6540c4b8ce60ef682cb28c
Autor:
Mira Lainiola, Katja Kuokkanen, Nelli Paasikoski, Mikko Myllymäki, Sanna K. Janhunen, Marja Vesajoki, Elena de Miguel, Olga Vekovischeva, Esa R. Korpi, Janne Kaskinoro, Anni-Maija Linden, Petri Hyytiä
Drugs of abuse induce widespread synaptic adaptations in the mesolimbic dopamine (DA) neurons. Such drug-induced neuroadaptations may constitute an initial cellular mechanism eventually leading to compulsive drug-seeking behavior. To evaluate the imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d39dbb5d6aef8a8893fde42bdc215fa9
http://hdl.handle.net/10138/323127
http://hdl.handle.net/10138/323127
Autor:
Elena, de Miguel, Olga, Vekovischeva, Katja, Kuokkanen, Marja, Vesajoki, Nelli, Paasikoski, Janne, Kaskinoro, Mikko, Myllymäki, Mira, Lainiola, Sanna K, Janhunen, Petri, Hyytiä, Anni-Maija, Linden, Esa R, Korpi
Publikováno v:
Addiction biologyREFERENCES. 24(6)
Drugs of abuse induce widespread synaptic adaptations in the mesolimbic dopamine (DA) neurons. Such drug-induced neuroadaptations may constitute an initial cellular mechanism eventually leading to compulsive drug-seeking behavior. To evaluate the imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d256277e4d4c42de7ccaa96d2c124e60
https://pubmed.ncbi.nlm.nih.gov/30421860
https://pubmed.ncbi.nlm.nih.gov/30421860
Publikováno v:
British Journal of Pharmacology. 171:4767-4784
Eating disorders, such as anorexia nervosa (AN), bulimia nervosa (BN) and binge eating disorders (BED), are described as abnormal eating habits that usually involve insufficient or excessive food intake. Animal models have been developed that provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4247ff164c10e0db8d559104899590ef
https://doi.org/10.1111/bph.12789
https://doi.org/10.1111/bph.12789
Publikováno v:
The International Journal of Neuropsychopharmacology. 17:169-186
The second-generation antipsychotic drug olanzapine has become a widely prescribed drug in the treatment of schizophrenia and bipolar disorder. Unfortunately, its therapeutic benefits are partly outweighed by significant weight gain and other metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ff8341ccf177e386536635f92f5aa3
https://doi.org/10.1017/s146114571300093x
https://doi.org/10.1017/s146114571300093x
Publikováno v:
Obesity. 21:E700-E708
Objective Anti-obesity drugs have adverse effects which limit their use, creating a need for novel anti-obesity compounds. We studied effects of dopamine (DA) and norepinephrine (NE) reuptake inhibitor bupropion (BUP), alone and after blocking α1- o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7405f2c3086c1f09bad89feb85012087
https://doi.org/10.1002/oby.20581
https://doi.org/10.1002/oby.20581
Publikováno v:
Obesity (Silver Spring, Md.), 19(10), 1979-1986. North American Association for the Study of Obesity
Because the use of monoamine reuptake inhibitors as weight-reducing agents is limited by adverse effects, novel antiobesity drugs are needed. We studied acute effects of the noradrenaline (NA) and serotonin (5-HT) reuptake inhibitor sibutramine (SIB)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e9b3172f19c2e9f029806bd7dbe122c
https://doi.org/10.1038/oby.2011.51
https://doi.org/10.1038/oby.2011.51
Autor:
Trine Ruby, Roger Wyler, Thomas Steckler, Heta Svärd, Theresa M. Ballard, Gaurav Kumar, Sanna K. Janhunen, Linda Lerdrup, Niels Plath, Marie Haman, John Talpos
Publikováno v:
Psychopharmacology. 232(21-22)
Current treatments for schizophrenia have modest, if any, efficacy on cognitive dysfunction, creating a need for novel therapies. Their development requires predictive animal models. The N-methyl-d-aspartate (NMDA) hypothesis of schizophrenia indicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b9294b7ba77c31f839b6c5b3283e0aa
https://pubmed.ncbi.nlm.nih.gov/26070547
https://pubmed.ncbi.nlm.nih.gov/26070547