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of 61
pro vyhledávání: '"K. JIN KIM"'
Autor:
Jill M. Siegfried, Austin M. Dulak, K. Jin Kim, The Minh Luong, Sanja Dacic, Stephanie R. Land, Jinling Yin, Jide Jin, Phouthone Keohavong, Mary E. Rothstein, Laura P. Stabile
The hepatocyte growth factor (HGF)/c-Met signaling pathway is involved in lung tumor growth and progression, and agents that target this pathway have clinical potential for lung cancer treatment. L2G7, a single potent anti-human HGF neutralizing mono
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1786ac6c6ef706348c753f3ad88b6f20
https://doi.org/10.1158/1535-7163.c.6531021.v1
https://doi.org/10.1158/1535-7163.c.6531021.v1
Autor:
Jill M. Siegfried, Austin M. Dulak, K. Jin Kim, The Minh Luong, Sanja Dacic, Stephanie R. Land, Jinling Yin, Jide Jin, Phouthone Keohavong, Mary E. Rothstein, Laura P. Stabile
Supplementary Fig. S1 from Therapeutic targeting of human hepatocyte growth factor with a single neutralizing monoclonal antibody reduces lung tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed8a521336690c29916e7c40536c7f5
https://doi.org/10.1158/1535-7163.22482858.v1
https://doi.org/10.1158/1535-7163.22482858.v1
Autor:
Daniel W. Fults, John Laterra, K. Jin Kim, Charles G. Eberhart, Bachchu Lal, Carolyn A. Pedone, Toba Niazi, Mandy J. Binning
Supplementary Table 1 from Hepatocyte Growth Factor and Sonic Hedgehog Expression in Cerebellar Neural Progenitor Cells Costimulate Medulloblastoma Initiation and Growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::837e94e10978f8e1da3caa482abcc027
https://doi.org/10.1158/0008-5472.22375676.v1
https://doi.org/10.1158/0008-5472.22375676.v1
Akademický článek
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Autor:
Emmanouil Fokas, Su Yin Lim, Keaton Jones, Jon N. Buzzelli, Ruth J. Muschel, Arseniy E. Yuzhalin, Bostjan Markelc, Yunhong Cao, Sean Smart, Alex Gordon-Weeks, K. Jin Kim
Publikováno v:
Hepatology. 65:1920-1935
Hepatic metastases are amenable to ablation; however, many patients are not suitable candidates for such therapy and recurrence is common. The tumor microenvironment is known to be essential for metastatic growth, yet identification of plausible targ
Publikováno v:
Molecular Cancer Therapeutics. 11:864-872
Expression of fibroblast growth factor 2 (FGF2) is believed to be a contributing factor to the growth of a number of tumor types, including hepatocellular carcinoma (HCC). However, the potential of monoclonal antibodies that neutralize FGF2 for treat
Autor:
Jill M. Siegfried, Laura P. Stabile, Phouthone Keohavong, K. Jin Kim, Stephanie R. Land, Mary E. Rothstein, Naftali Kaminski, Autumn Gaither-Davis, Diana Lenzner
Publikováno v:
Cancers
Cancers, Vol 2, Iss 4, Pp 2153-2170 (2010)
Cancers; Volume 2; Issue 4; Pages: 2153-2170
Cancers, Vol 2, Iss 4, Pp 2153-2170 (2010)
Cancers; Volume 2; Issue 4; Pages: 2153-2170
EGFR and c-Met are both overexpressed in lung cancer and initiate similar downstream signaling, which may be redundant. To determine how frequently ligands that initiate signaling of both pathways are found in lung cancer, we analyzed serum for hepat
Autor:
Daniel W. Fults, Charles G. Eberhart, Bachchu Lal, John Laterra, K. Jin Kim, Carolyn A. Pedone, Mandy J. Binning, Toba N. Niazi
Publikováno v:
Cancer Research. 68:7838-7845
Medulloblastomas are malignant brain tumors that arise by transformation of neural progenitor cells in the cerebellum in children. Treatment-related neurotoxicity has created a critical need to identify signaling molecules that can be targeted therap
Autor:
K. Jin Kim, G. Yancey Gillespie, Bachchu Lal, Yi Chi Su, Lihong Wang, John Laterra, Amandeep Salhotra
Publikováno v:
Clinical Cancer Research. 12:1292-1298
PURPOSE: Hepatocyte growth factor (HGF) and its receptor Met are involved in the initiation, progression, and metastasis of numerous systemic and central nervous system tumors. Thus, an anti-HGF monoclonal antibody (mAb) capable of blocking the HGF-M
Autor:
Kelly H. Dodge, Kurt Schroeder, Avi Ashkenazi, Hartmut Koeppen, Katharine Grimmer, Scot A. Marsters, Anan Chuntharapai, K. Jin Kim
Publikováno v:
The Journal of Immunology. 166:4891-4898
To explore an approach for death receptor targeting in cancer, we developed murine mAbs to human death receptor 4 (DR4). The mAb 4H6 (IgG1) competed with Apo2L/TNF-related apoptosis-inducing ligand (DR4’s ligand) for binding to DR4, whereas mAb 4G7