Zobrazeno 1 - 6
of 6
pro vyhledávání: '"K. J. Wirth"'
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 73:797-804
The availability of potent and stable bradykinin antagonists has had a tremendous impact on kinin research. This article reviews the current status of research on kinin antagonists, describes their chemical properties, and delineates recent advances
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec5aa1723cca97710ecd243b7894b51
https://doi.org/10.1139/y95-108
https://doi.org/10.1139/y95-108
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 291(2)
ATP-sensitive potassium (K(ATP)) channels are activated during myocardial ischemia. The ensuing potassium efflux leads to a shortening of the action potential duration and depolarization of the membrane by accumulation of extracellular potassium favo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c0304c3eb55b92ad55c4b866a4a04b6f
https://pubmed.ncbi.nlm.nih.gov/10525061
https://pubmed.ncbi.nlm.nih.gov/10525061
Publikováno v:
Digestive diseases and sciences. 44(4)
Dextran sulfate sodium-induced colitis in mice has been recognized as a model for human ulcerative colitis. Using this model, we carried out a study on the preventive effect of Icatibant, a bradykinin B2 receptor antagonist previously called HOE 140,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ddccccbcbaa28abe0f6041ed5ccf186
https://pubmed.ncbi.nlm.nih.gov/10219847
https://pubmed.ncbi.nlm.nih.gov/10219847
Publikováno v:
Inflammopharmacology. 6(1)
The present study aimed to evaluate the effect of Hoe 140, a BK receptor B(2) antagonist, on acute oedema induced by carrageenan, BK and kaolin in male Wistar Kyoto rats. Hoe 140 (0.2 mg/kg and 20 mg/kg) given ip caused significant (p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::962202898d56f856af48bfb89ca8adf5
https://pubmed.ncbi.nlm.nih.gov/17638123
https://pubmed.ncbi.nlm.nih.gov/17638123
Publikováno v:
Agents and actions. Supplements. 38
DesArg10[Hoe 140] and Des(D-Arg1, Arg10)[Hoe 140], desArg10-analogs of the potent and stable B2 bradykinin (BK) receptor antagonist Hoe 140 were found to be potent and stable antagonists of the B1 receptor in vitro and in vivo. They were, however, le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::01f8dfc7fb01ef94f55faefd7231f694
https://pubmed.ncbi.nlm.nih.gov/1334341
https://pubmed.ncbi.nlm.nih.gov/1334341
Publikováno v:
Agents and actions. Supplements. 38
The new and highly potent B2 bradykinin (BK) antagonist Hoe 140 was tested for its ability to inhibit oedema of rat paws induced by scalding and carrageenan. The data show that Hoe 140 inhibits scalding and carrageenan oedema for more than four and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::493b54431012a143a8c834ba2ff7521e
https://pubmed.ncbi.nlm.nih.gov/1462876
https://pubmed.ncbi.nlm.nih.gov/1462876