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pro vyhledávání: '"K. J. Tracey"'
Akademický článek
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Autor:
S I, Valdés-Ferrer, M, Rosas-Ballina, P S, Olofsson, B, Lu, M E, Dancho, M, Ochani, J H, Li, J A, Scheinerman, D A, Katz, Y A, Levine, L K, Hudson, H, Yang, V A, Pavlov, J, Roth, L, Blanc, D J, Antoine, S S, Chavan, U, Andersson, B, Diamond, K J, Tracey
Publikováno v:
Journal of Internal Medicine
Background More than 500,000 hospitalized patients survive severe sepsis annually in the USA. Recent epidemiological evidence, however, demonstrated that these survivors have significant morbidity and mortality, with 3-year fatality rates higher than
Publikováno v:
Journal of internal medicine. 276(5)
Autor:
K ÅKERLUND, H ERLANDSSON HARRIS, K J TRACEY, H WANG, T FEHNIGER, L KLARESKOG, J ANDERSSON, U ANDERSSON
Publikováno v:
Clinical and Experimental Immunology. 115:32-41
SUMMARYA recently developed compound, a multivalent guanylhydrazone (CNI-1493) that inhibits TNF-α production by suppressing TNF-α translational efficiency, was administered in an experimental model of collagen type II-induced arthritis in DA rats.
Autor:
J M, Huston, K J, Tracey
Biological therapeutics targeting TNF, IL-1, and IL-6 are widely used for treatment of rheumatoid arthritis, inflammatory bowel disease, and a growing list of other syndromes, often with remarkable success. Now advances in neuroscience have collided
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a1ae02d39a9b3aa0e1eb8b1b8644e117
https://europepmc.org/articles/PMC4527046/
https://europepmc.org/articles/PMC4527046/
Publikováno v:
Update in Intensive Care and Emergency Medicine ISBN: 9783540301578
As reviewed above, there is abundant evidence implicating autonomic dysfunction or cytokine excess in diseases with inflammatory pathology such as sepsis, Crohn’s disease, and rheumatoid arthritis. The identification of a vagus nerve mechanism that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc4c06d45c2a8fe4edd5bc4459c54404
https://doi.org/10.1007/3-540-30328-6_18
https://doi.org/10.1007/3-540-30328-6_18
Autor:
K. J. Tracey
Publikováno v:
Tissue Oxygenation in Acute Medicine ISBN: 9783540425953
Tissue Oxygenation in Acute Medicine
Tissue Oxygenation in Acute Medicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::daca2b7ff73912cf645709c9d1b48fd6
https://doi.org/10.1007/978-3-642-58268-4_23
https://doi.org/10.1007/978-3-642-58268-4_23
Autor:
K. J. Tracey, H. Wang
Publikováno v:
Immune Response in the Critically Ill ISBN: 9783540425892
The macrophage is a central participant in the development of septic shock, acute respiratory distress syndrome (ARDS), inflammatory bowel disease, and rheumatoid arthritis. In these, and other inflammatory diseases, macrophages release excessive qua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e02f9ebe207c94fd624a9671693f0e9b
https://doi.org/10.1007/978-3-642-57210-4_10
https://doi.org/10.1007/978-3-642-57210-4_10
Publikováno v:
Surgery. 126(2)
Cytokines mediate the metabolic and physiologic responses to injury and infection. Anterior pituitary cells express receptors for tumor necrosis factor (TNF) and interleukin 1 (IL-1), which can signal these cells to release corticotropin, growth horm
Publikováno v:
Surgery. 126(2)
Tumor necrosis factor alpha (TNF alpha) has been implicated as an important mediator in acute pancreatitis-associated adult respiratory distress syndrome, but the precise pathogenesis remains unclear. The purpose of this work was to clarify the role