Zobrazeno 1 - 4
of 4
pro vyhledávání: '"K. J. Gorelick"'
Autor:
James O. Kahn, A Bostrom, John G. Gambertoglio, R Williams, G Gatti, K J Gorelick, C J Arri, J D Lifson
Publikováno v:
Antimicrobial Agents and Chemotherapy. 38:260-267
GLQ223 is a highly purified single-chain ribosome-inactivating protein with selective effects against a variety of cells, including macrophages infected with human immunodeficiency virus. We evaluated the safety, pharmacokinetics, and immunologic eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de27f9ca7a03dc0346ee352bd517f08f
https://doi.org/10.1128/aac.38.2.260
https://doi.org/10.1128/aac.38.2.260
Autor:
K. J. Gorelick, E. Lim, D. M. Fishwild, D. M. Wood, D. T. Reardan, K. D. Knebel, J. B. Parent, P. J. Conlon, P. W. Trown
Publikováno v:
Host Defense Dysfunction in Trauma, Shock and Sepsis ISBN: 9783642774072
Sepsis is a common, life-threatening complication of infection with gram-negative bacteria. While the pathophysiology of gram-negative sepsis has not been fully elucidated, a significant portion of the clinical syndrome can probably be attributed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7e4a79125a68e7c3f0e0a675e63734e
https://doi.org/10.1007/978-3-642-77405-8_156
https://doi.org/10.1007/978-3-642-77405-8_156
Autor:
K J, Gorelick, H, Chmel
Publikováno v:
Infectious disease clinics of North America. 5(4)
Immunologic targeting of the mediators of sepsis is a new approach to reducing mortality associated with this often-fatal complication. When sepsis is due to infection with a gram-negative pathogen, endotoxin plays a key role in its pathogenesis. Ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0657835a340cbc06d0df44dcb7053e62
https://pubmed.ncbi.nlm.nih.gov/1783775
https://pubmed.ncbi.nlm.nih.gov/1783775
Publikováno v:
Progress in clinical and biological research. 367
Xomen-E5 (E5) is a murine monoclonal IgM antibody (MAb) that binds to the lipid A epitope of endotoxin. The MAb was developed by immunization against the J5 mutant of Escherichia coli. Prior studies in humans have shown safety and T1/2 of 18.4 hours.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::022795b1d8ab88b6558aba1a24efb83a
https://pubmed.ncbi.nlm.nih.gov/1924426
https://pubmed.ncbi.nlm.nih.gov/1924426