Zobrazeno 1 - 10
of 21
pro vyhledávání: '"K. J. Al-Ghoul"'
Publikováno v:
Experimental Eye Research. 89:344-357
This study characterized early structural changes at posterior fiber ends in the crystalline lens after diabetic induction. Wistar rats (n = 49), randomized into one naïve control group and four experimental groups, were rendered diabetic via strept
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 1, Pp 198-211 (2003)
Simvastatin rapidly induced cataracts in young Chbb:Thom (27) but not Sprague Dawley (SD) or Hilltop Wistar (HW) rats. Oral treatment for 14 but not 7 days committed CT rat lenses to cataract formation. The cholesterol to phospholipid molar ratio in
Autor:
K. J. Al-Ghoul, Jerome R. Kuszak
Publikováno v:
Optometry and Vision Science. 79:193-204
Purpose. To correlate specific parameters of lens structure (anterior and posterior suture branch length and planar area) with variability in back vertex distance (BVD) and scatter in rabbit lenses as a function of development, growth, and age. Metho
Autor:
Christopher D. Freel, K. J. Al-Ghoul, Jer R. Kuszak, Rachel K. Nordgren, M. Joseph Costello, Adam J. Kuszak
Publikováno v:
Experimental Eye Research. 72:199-214
This study was conducted to quantify structural change associated with human nuclear fiber compaction as a function of ageing and nuclear cataract formation. Normal donor lenses in three age ranges, young (15–25 years), middle-aged (36–46 years)
Publikováno v:
Experimental Eye Research. 67:163-177
The Royal College of Surgeons (RCS) rat is an animal model for human autosomal recessive retinitis pigmentosa. As the retinas of these animals degenerate from two to six weeks after birth, posterior subcapsular cataracts (PSCs) develop, presumably in
Autor:
K. J. Al-Ghoul, M. J. Costello
Publikováno v:
Experimental Eye Research. 57:469-486
The ultrastructure of human diabetic lens nuclei is described for the first time. Two cataractous lenses from late-onset diabetics were examined using transmission electron microscopy to determine the type and distribution of cellular disruptions. Th
Publikováno v:
Anatomical record (Hoboken, N.J. : 2007). 293(11)
This study describes a novel cytoskeletal array in fiber cells of the ocular lens of the rat and shows its relationship to the classical terminal web of other epithelial tissues. Naive adult Sprague-Dawley rats (n = 28) were utilized. F-actin, fodrin
Publikováno v:
The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology. 273(2)
In this study we used correlative light, scanning, and transmission (freeze-etch) electron microscopy to characterize lens structure in normal mice and compare it with that in mice deficient in the major intrinsic protein (MIP) of fiber cells. Grossl
Publikováno v:
Molecular vision. 5
To document lens ultrastructure during and after internalization of posterior subcapsular cataracts (PSCs) in Royal College of Surgeons (RCS) rats, a model for human autosomal retinal degenerative disease.RCS rat lenses at 2, 2.5, 3, 4, 6, 9, 12, and
Publikováno v:
Molecular vision. 5
The Royal College of Surgeons (RCS) rat is an animal model for human retinal degenerative disease and posterior subcapsular cataracts (PSCs). The purpose of this study was to correlate the structure and optical quality of RCS lenses with PSCs as a fu